Unfolding potential

In the thesis the dynamics of strategies is studied from two perspectives.In the first part of the thesis strategies are considered to be opinions present in a community.

In this thesis, dynamic testing principles were applied to examine young children's potential for learning. Our studies focused on the role of cognitive flexibility, to further increase our understanding of the cognitive processes involved in children's ability to learn from instruction and feedback,…

An assessment approach that tailors to children’s instructional needs

Can dynamic testing provide us with insight in children’s potential for learning?

BlaC is the β-lactamase of Mycobacterium tuberculosis. We show that it can recover from inhibition by clavulanic acid and that phosphate helps it do so.

This thesis introduces the concept of

Dynamical systems describe the evolution of objects in a space over time and may be used to model physical phenomena. Due to this, much research is dedicated to understanding the mathematics of dynamical systems.

Promotor: Prof.dr. S.F. Portegies Zwart, Co-promotor: D.C. Heggie

In this unique collaboration between Leiden, Delft and Erasmus and building on the goals set in the African Union Agenda 2063 the United Nations Agenda 2030, this multidisciplinary minor fosters a deeper understanding of integrated and sustainable approaches in Africa.

The research of our group is centered around dynamical systems, functional analysis and their interplay.

Dynamic nuclear polarization with paramagnetic agents can enhance nuclear magnetic resonance signals by orders of magnitude. The mechanism of enhancement depends a.o. on the magnetic resonance properties of the agents used. Electron spin relaxation times at NMR relevant magnetic field/microwave frequencies,…

Phospholipase A/acyltransferase 3 (PLAAT3) and PLAAT4 are enzymes involved in the synthesis of bioactive lipids. Despite sequential and structural similarities, the two enzymes differ in activity and specificity.

Promotor: W.Th.F. den Hollander

Heterogeneous catalysis is one of the fundamental processes of modern life, being common in industrial refinery and hydrogen vehicles, all the way to the living cell. The dissociation of H2 on Cu(111) is an important benchmark system for studying heterogeneous catalysis, with a large and varied amount…

If gifted children are experts in using strategies, why do they experience problems with learning? Why do they underachieve?

Promotor: Prof.dr. W.Th.F. den Hollander, Co-promotor: R. Fernandez

The research of this programme is centered around dynamical systems, functional analysis, and their interplay.

Thermodynamics is one of the founding scientific pillars that has helped us better understand heat engines, biology, ecosystems, and even black holes. While it fundamentally describes large systems by examining the bulk behavior of their constituents, it is anchored in the statistical equivalence of…

Promotor: J.W. van Holten

Promotor: Huub de Groot, Co-promotor: Francesco Buda

Promotor: H.J. van den Herik, B.R. Katzy, Co-promotor: K. Sailer

Throughout all domains of life, from bacteria and archaea to eukaryotes, genomes adopt well-organized three-dimensional structures that can change in space and time to accommodate preferred transcriptional programs for environmental adaptation, the maintenance of cellular identity and differentiation…

What is the relationship between outcomes of dynamic testing and cognitive flexibility in young children?

Promotor: S.M. Verduyn Lunel, Co-promotoren: M.F.E. de Jeu, S.D. Silvestrov

Chemical reactions go hand-in-hand with an energy exchange with the environment in which they take place. Surfaces offer a variety of energy dissipation channels, constituted by the nuclear and electronic degrees of freedom of the atoms at the interface. Aiming at an improved future harvesting of energy,…

Promotor: Promotor: W.Th.F. den Hollander, Co-promotor: V. Sidoravicius.

The genomic DNA of every organism is organized and compacted in order to fit inside the cell. This is achieved by the joint action of numerous architectural proteins that aid in folding the genome. Genome folding is tightly interconnected with transcription, with genes in certain regions being silenced,…

For optimization problems, it is often unclear how to choose the most appropriate optimization algorithm. As such, rigorous benchmarking practices are critical to ensure we can gain as much insight into the strengths and weaknesses of these types of algorithms.

Cell adhesion signaling

This minor focuses on how our thoughts, emotions and behaviour are influenced by other people, and how we influence other people.

What is the optimal investment policy according to which a firm adapts its capacity in a competitive market?

Promotor: Prof.dr. G.J. Kroes

Chromatin is an ubiquitous protein-DNA complex that forms the structural basis of DNA condensation in all eukaryotic organisms.

Schemas are knowledge structures that allow us to make efficient judgments about the world without the cost of memorizing every detail of previous experiences. It has long been known that schemas can enhance long-term memory for related information.

In the early universe, the dynamics of the Higgs field can give rise to many interesting phenomena.

When a star gets too close to a supermassive black hole, it is torn apart by strong tidal forces in a tidal disruption event (TDE).

Catalysis is of extreme relevance in the production of everyday materials and plays a central role in many aspects of our life.

To what extent do aspects of fluency fluctuate throughout time? And how do raters take the dynamicity of fluency into account when rating performances?

The solar system was formed approximately 4.56 billion years ago. Despite the numerous theories that have been developed over the years, the formation and evolution of the solar system still remain unclear.

Promotor: Prof.dr. T. Schmidt, Co-Promotor: Dr. ir. S.J.T. van Noort

Fundamental understanding of molecular reactions on metal surfaces is important for improving heterogeneous catalysis.

Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M. Bongards (Cologne University)