What are the biological effects of Chinese herbal medicine in regulation of cancer cell metastasis?

Can we link multiple components from herbal extracts with their biological activities?

Promotor: Prof.dr. E.F. Smets, Co-promotor: T.R. van Andel

The main aim of my Ph.D. thesis is to further explore the value of using early developing zebrafish larvae (up to 5 dpf) as a model to study anxiety-like behaviour and their pharmacological modulation with drugs.

Chair of LU-European Center for Chinese Medicine and Natural Compounds, Institute of Biology, Leiden University - the Netherlands

The Metabolomics Facility of the University of Leiden has brought together two research groups from the Faculty of Science that are well-known for their expertise in two different fields: the Biomedical Metabolomics Facility Leiden, experts in clinical metabolomics and the Natural Products Laboratory,…

Promotor: Jan van der Greef; Co-promotors: Mei Wang; Eduard van Wijk

This study documents and translates the Saa (Zapotec) cultural heritage of the Bene’ Ya’a/En’ne I’ya peoples, the Zapotec inhabitants of the Sierra Norte of Oaxaca.

Dr. Mei Wang, chair of ‘Leiden University - European Center for Chinese Medicine and natural compounds’ has been awarded the ‘Qihuang prize’. The prize is awarded by the Chinese Medicine Society in recognition of her significant contribution to Chinese medicine outside China and to further stimulate…

In the interests of knowledge exchange and research, a delegation from the China Academy of Chinese Medicinal Sciences (CACMS) in Beijing paid a visit to the Hortus botanicus in Leiden. The visit was part of a joint research study on herbal medicine.

An international research consortium led by Bob van de Water, Professor of Toxicology at Leiden University, has been awarded a prestigious Horizon2020 grant of 30 million euros.

During orange juice production only around a half of every orange is turned into juice. Lizah van der Aart and Blair Berger, both MSc-students at the IBL, and Ryan Bogaars from Delft University, received an NWO-scholarship to develop a novel method to extract natural products from orange residue.

An international team from the Netherlands, France, Norway and Austria demonstrate how new sequencing technologies can be used to efficiently generate the genome, DNA, sequence of an endangered animal, the European Eel.

Skilful watercolours by botanical painter Esmée Winkel, anatomical flower models and the odd stunning real orchid. In the Extraordinary Orchids exhibition at Oude UB, the Hortus botanicus shows us the wonderful world of the orchid.

What do a novel anti-ageing ingredient for cosmetics and a new type of chicken feed have in common? They were both produced using a new solvent developed by Leiden biologists in 2011. The medium is neither solid nor liquid, and the industry is now starting to see it’s many possibilities.

Endocannabinoids - the body's own marijuana - are promising departure points for drug research. Professor of Molecular Physiology Mario van der Stelt examines whether inhibiting their production can be a way to fight inflammatory brain disease and to combat obesity. Inaugural lecture 19 October.

What chemicals do plants have available, and what happens if they use them when faced with bacteria or fungi? That is what PhD candidate Luis Salomé Abarca is keen to learn. He studies plants’ survival and their use of chemical components in communication and defence. Salomé Abarca works at the Natural…

An international consortium of research groups is aiming to develop novel antibiotics against the tuberculosis bacteria and two other deadly bacteria. The European Union has awarded a total of 18 million euros to the RespiriTB and RespiriNTM projects. Researchers from the Leiden University Medical Centre…

The Faculty of Science forges new research collaborations with the Institut Teknologi Bandung in Indonesia in the fields of tropical diseases, e.g. tuberculosis and medical biotechnology.

Leiden University is partner of the Netherlands Centre for One Health (NCOH). This initiative brings together leading academic research institutes in the Netherlands in an open innovation network that responds to the theme: One Health. NCOH interviewed Doris van Bergeijk: PhD student of the project…

Researchers from the Institute of Biology Leiden have discovered how good intestinal bacteria regulate our innate immune system. This surprising discovery could make it possible to treat diseases related to inflammation, such as diabetes and colitis, with a cocktail of good bacteria. Publication in…

David Versluis successfully simulated an infant gut virtually. This is crucial for research on improvements in formula milk. Currently, such research primarily relies on diaper contents, which is not optimal. Versluis defended his doctoral thesis on April 23.

Herman Spaink knows of many substances that may help combat tuberculosis. Lab space to study them safely is very limited in Leiden. A brand-new lab at Universitas Gadjah Mada in Indonesia will soon provide a solution. About time, says Spaink, ‘The disease is on the rise and is becoming less sensitive…

The first phase of the construction of the new building for the Faculty of Science is finished. The Cell Observatory of the Institute of Biology Leiden will be moving to the new building on the 19th of May.

Edith Schippers, Minister of Health, will be investing six million euros over the coming four years to boost research on new antibiotics. The programme will be set up by several different parties, including the Leiden Centre for Antimicrobial Research.

To develop good cancer treatments, we need to know much more about how malignant tumour cells develop. Professor Ewa Snaar-Jagalska looks at not just the effect of medication on isolated cells but also the behaviour of cancer cells in their tissue environment. Inaugural lecture on 11 December.

From the 11th of May Ewa Snaar-Jagalska has been appointed Professor in the field of cellular tumor biology within the Faculty of Science at the Institute of Biology Leiden. Her research focuses on the cellular tumor biology and human cancer modeling in zebrafish

Zebrafish-human communication shows that cancer cells lacking a signaling protein are less able to develop aggressive metastatic properties. This discovery has been made by molecular cell biologist Claudia Tulotta. PhD defence 14 June.

Valedictory lecture

Maarten Jansen, professor emeritus at the Faculty of Archaeology, was appointed as Distinguished Emeritus Professor for two years at the University of Bonn. In this position, Jansen, a world-renowned specialist on ancient Mexican pictorial manuscripts, will further expand upon the long-standing collaboration…

The Pilgrims to America exhibition at Museum De Lakenhal inspires reflection. How far do you go in the quest for freedom? It focuses on the Pilgrims’ relationship with the University and which knowledge they took with them from Leiden.

Few researchers see potential in research on glioblastoma, an incurable brain tumour. Alexander Kros brought together colleagues who are up to the challenge. European research funder ERC recently made 10.6 million euros available, a year earlier NWO provided 3 million euros. ‘In six years, we certainly…

Arianna Pranger has lost her heart to teaching. A senior lecturer on the master’s programme in Pharmacy, she won the LUS Teaching Prize 2020. The programme trains students to be pharmacists.

Persian stories with beautiful miniatures, letters on papyrus from Egyptian traders and medicinal manuscripts translated from Greek and edited in Arabic. Studium Generale organizes a lecture series on the world-famous manuscripts from the Middle East collection of Leiden University Libraries (UBL).…

Genes predict whether you have a propensity for an illness but environmental factors often have the last word: nutrition, air pollution, lifestyle, stress. The exposome as both culprit and chance. Large-scale research is being carried out into this at Leiden. Thomas Hankemeier, Professor of Analytical…