Treatment with special stem cells seems to be a good option for suppressing the immune system in organ transplants. Researchers are trying to learn from processes that take place in the human body during pregnancy.

LOTS 2025 will take place between 6-9 July 2025 in Leiden, the Netherlands. The number of places is limited. After you send in your application, you will hear if you are selected to join LOTS in May. The fee for participants will be 100 euros to cover the costs for accommodation and food.

The LUMC is the first medical institution in the world to offer a Massive Open Online Course (MOOC) on clinical kidney and pancreas transplantation.

Kidney transplantation is a major advance of modern medicine. This course will give you state of the art updates about what used to be an experimental, risky, and very limited treatment option more than 50 years ago and is now routinely performed in many countries worldwide.

Promotor: C.A.J. Knibbe, Co-promotor: J.J. Boelens, R.G.M. Bredius

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Kidney transplantation used to be an experimental risky procedure, but is now routinely performed by many countries worldwide.

Our immune system protects us against disease, but every now and then, something goes wrong: an enemy invades our bodies or our immune system attacks our own cells and we become ill. Doctors and researchers at the Leiden University Medical Center (LUMC) want to be able to manipulate the immune system…

The LUMC has a longstanding tradition researching the role of the immune system in infectious diseases, transplantation and auto-immune diseases.

The organ in the Great Auditorium in the Academy Building has been played at walk-in concerts and University celebrations since 1998.

Great Auditorium Organ Foundation is a Public Benefit Organisation (Algemeen Nut Beogende Instelling, ANBI)

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The long term goal of the Biophysical Organic Chemistry/SSNMR group, headed by Prof. Huub de Groot, is to reach an understanding of structure, dynamics and functional mechanisms of membrane proteins and self-organized biological assemblies and to translate this knowledge into new concepts for nano-devices,…

Throughout all domains of life, from bacteria and archaea to eukaryotes, genomes adopt well-organized three-dimensional structures that can change in space and time to accommodate preferred transcriptional programs for environmental adaptation, the maintenance of cellular identity and differentiation…

This volume challenges the idea that the development of ‘democracy’ is a story of rise and progress at all. It is rather a story of continuous but never completely satisfying attempts of interpreting the rule of the people.

Promotor: G.R. de Snoo

How do leadership behaviour repertoires take shape in public organizations?

The research in the Biosyn group is focused on the design, synthesis and function of the four major types of biomolecules: nucleic acids, carbohydrates, peptides and lipids and hybrid structures thereof. These biomolecules and their derivatives are used in drug discovery and chemical biology, to develop…

Physicians and researchers of the Leiden University Medical Center (LUMC) and Leiden University are working on therapies for restoring damaged organs such as hearts and kidneys. They are even trying to construct tailor-made organs. Read more on this topic in the new science dossier on Vascular and Regenerative…

Stars like the sun are born in large molecular clouds existing from gas and dust. During the formation process, the chemical composition of the material can be altered drastically by the changing physical conditions.

Charisma K. Lepcha (PI, Sikkim University), Pradyut Guha (co-PI, Sikkim University), Rajib Sutradhar (co-PI, Christ University Bangalore) and Erik de Maaker (Leiden University) have been awarded a two-year grant of USD 18.000 to conduct research on the impact of ‘green farming’ on the sensitive mountain…

Methods of treatment for chronic illnesses are limited. Doctors and researchers at Leiden University Medical Center (LUMC) and Leiden University are working on new therapies as an alternative for organ transplants. The goal is to cure the illnesses by restoring organs to their original function. Stem…

Complex Organic Molecules (COMs) have been detected in objects across different stages of stellar evolution.

Hydrogen peroxide (H2O2) is an important bulk chemical that is used in various industrial processes. More than 95% of the H2O2 used in industry is made via the anthraquinone process during which a large amount of energy is going to waste.

My research focusses on site-specific compositional and performance practices of music for organ and electronics and their musical-spatial values.

Our in-house human skin equivalents contain all stratum corneum (SC) barrier lipid classes, but have a reduced level of free fatty acids (FAs), of which a part is mono-unsaturated. These differences lead to an altered SC lipid organization and thereby a reduced barrier function compared to human skin.…

Growing public backlash against international organizations (IOs) and attacks of national political elites on the rule of law increasingly challenge governance by IOs.

Regenerative medicine is a new way of treatment that helps impaired cells, tissues, and organs work well again. We do this by repairing, replacing, or restoring cells, tissues, and organs after damage from illness or injury. This includes treating long-term diseases such as diabetes, kidney diseases,…

Mechanical forces are known to play an important role in bacterial colonies. In this dissertation, we study the self-organization at various stages of growing bacterial colonies, and focus on the mechanical effects of cell growth.

Organic amendments applied to agricultural fields can partially offset our carbon emissions to the atmosphere and improve the resilience of agriculture to the effects of climate change. Driving these benefits, however, are complex and poorly understood interactions between organic amendment properties,…

Cardiovascular disease is the number one cause of death worldwide. The most important risk factor for developing this disease is high cholesterol levels in the blood.

Transplantation of labial salivary glands to the eyelids for patients with dry eye appears to give excellent results clinically.

Bacteria often experience external challenges, such as changes in environmental conditions or attacks by bacteriophages.

The Future of Multilateralism addresses current challenges and future perspectives of international and regional organizations. It aims to uncover how stable the foundations of global cooperation really are, particularly in the light of the latest unilateral and protectionist practices of international…

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The central theme of the NWO-project ‘The Promise of Organization’ is the evolution of political organization during the 19th century. We focus on the enthusiasm, arguments and concrete activities of the organizers as well as the criticism offered by opponents of modern political organization.

Petra van der Bekerom, Joris van der Voet, and Johan Christensen, three assistant professors at Leiden University, conducted a large-scale survey experiment about whether citizens are more negative about failing service delivery than private organizations.

Netherton Syndrome (NTS) is a rare genetic skin disease caused by mutations in the serine protease inhibitor Kazal-type 5 gene, which encodes the lympho-epithelial Kazal-type-related inhibitor. NTS patients have a profound impaired skin barrier function. Because SC lipids play a crucial role in the…

Do recent developments in the European security architecture signal the end of multilateral cooperation, or the beginning of a new era with emerging forms of international security collaboration?

It is the aim of this project to better understand how the physical properties of lipids influences the structure and overall barrier function of the skin.