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1,147 search results for “bart cancer” in the Public website

• Exploring Grainyhead-like 2 target genes in breast cancer Research output

  The objective of this study was to investigate the expression and function of GRHL2 in different breast cancer subtypes.

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  Bart Bulsing Technical Information Manager / Draftsman

  Service Unit Real Estate

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  Bart Hoenen Advisor Entrepreneurship (guest

  LURIS

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  Bart Stastny research assistant

  Faculty of Humanities

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  Bart Mertens
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  Bart Gorissen Lecturer

  Faculty of Law

• RNA splicing in breast cancer progression Research output

  In this thesis, we aimed to better understand the underlying mechanisms involved in TNBC progression and metastasis formation and discover new targets to reduce breast cancer related deaths.

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  Bart Gorissen Lecturer

  Faculteit der Rechtsgeleerdheid

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  Bart Wentholt Participating Coordinator MDA Open Access

  Leiden University Libraries

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  Bart Alewijnse Programmer/lab technician

  Faculty of Humanities

• Novel regulators of prostate cancer stem cells and tumor aggressiveness Research output

  Promotor: R.C.M. Pelger Co-Promotor: G. van der Pluijm

• Cancer and heredity Research Dossier: Cancer pathogenesis and therapy

  Some people are predisposed to develop cancer. Mutations in genetic material that increase a person’s chances of developing cancer can already be present at birth. Researchers are closely examining these mutations to learn more about how cancer begins to develop.

• Cancer pathogenesis and therapy Research Dossier

  With cancer, a person’s body cells grow uncontrollably. Putting together a detailed picture of how this comes about makes it possible to develop efficient therapies. Researchers at the Leiden University Medical Centre (LUMC) and Leiden University are working together to gain a better understanding…

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  Bart Vogelaar Assistant professor

  Faculty of Social and Behavioural Sciences

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  Bart Lenselink Guest Scientist

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  Bart Zantvoort Lecturer

  Faculty of Humanities

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  Bart Wielders PhD candidate / self funded

  Faculteit Governance and Global Affairs

• Cancer Drug Target Discovery Research project

  We focus on a better understanding of the mechanisms of cancer drug resistance and metastasis.

• BRCA1-associated breast cancer: finding new weapons for an old villain Research output

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• Cancer Pathogenesis and Therapy Research project

  Cancer represents a formidable current and future global health challenge. The LUMC medical research profile Cancer Pathogenesis and Therapy charges this challenge by developing and implementing innovative patient-tailored, multimodal diagnostic methods and treatment modalities.

• Cancer Drug Target Discovery

  In this research group, headed by Prof. Erik Danen, the aim is to unravel cellular signaling mechanisms in normal and diseased cells, with a long-standing interest in cell adhesion signaling. In complex multicellular organisms such as ourselves, a division of labor emerges where different tissues and…

• Identification of novel targets in prostate cancer progression Research output

  Promotor: Prof.dr. B. van de Water, Co-promotor: E.H.J. Danen

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  Bart van Hoek Professor emeritus

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  Bart Schreuders Researcher/lecturer

  Faculteit der Rechtsgeleerdheid

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  Bart Roep Professor

• Discovery of BUB1 kinase inhibitors for the treatment of cancer Research output

  The spindle-assembly checkpoint (SAC) is a safety mechanism which secures accurate chromosome segregation during mitosis.

• Cancer Therapeutics and Drug Safety Cell Systems and Drug Safety

  In this research group, headed by Bob Van de Water, cell signaling programs that underlie adverse drug reactions as well as cancer development and progression are unraveled. Adverse drug reactions involve cell injury in critical target organ cells which leads to the activation of cellular stress response…

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  Bart de Vries Guest

  Faculty of Social and Behavioural Sciences

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  Bart de Jongh Lecturer

  Social & Behavioural Sciences

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  Bart Schermer Professor

  Faculteit der Rechtsgeleerdheid

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  Bart Joosen Guest lecturer

  Faculteit der Rechtsgeleerdheid

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  Bart Collard External PhD candidate

  Faculteit der Rechtsgeleerdheid

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  Bart Labuschagne Lecturer

  Faculteit der Rechtsgeleerdheid

• Unravelling cancer drug resistance mechanisms Research project

  Mechanisms fro drug resistance

• Cancer chess: molecular insights into PARP inhibitor resistance Research output

  The clinical potential of applying synthetic lethality to cancer treatment is famously demonstrated by the BRCA1/PARP1 paradigm: a tumor specific defect in BRCA1 – a component of the DNA double-strand break (DSB) repair pathway homologous recombination (HR) – results in a remarkable sensitivity to PARP1…

• multifaceted roles of Grainyhead-like transcription factor-2 in breast cancer Research output

  Breast cancer is the most common cancer in women worldwide. Metastasis, the process by which cancer cells spread to other parts of the body, makes treatments less effective. It is important to unravel the mechanism of metastasis.

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  Bart Verkuil Associate Professor

  Faculty of Social and Behavioural Sciences

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  Bart Schuurman Professor

  Faculteit Governance and Global Affairs

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  Bart Verheijen Assistant professor

  Faculty of Humanities

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  Bart Custers Professor of Law and Data Science

  Faculteit der Rechtsgeleerdheid

• Patient-derived models of breast cancer: a breakthrough story of the duct Research output

  To improve treatment of breast cancer patients it is important to understand all stages of breast cancer from initiation to in situ disease and progression to invasive disease. In this thesis we use intraductal injections of patient derived tissue to model ductal carcinoma in situ and invasive breast…

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  Bart Monsma-Hempel Program manager of Educational Logistics

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  Bart Barendregt Dean/professor

  Faculty of Social and Behavioural Sciences

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  Bart Krans Professor of Private Law and Civil Procedure

  Faculteit der Rechtsgeleerdheid

• PI3K signaling and adherens junctions in invasive lobular breast cancer Research output

  Invasive lobular carcinoma (ILC) is the second most common type of breast cancer.

• Cancer cells: A closer look Research Dossier: Cancer pathogenesis and therapy

  What distinguishes a tumour cell from a healthy cell? Researchers are trying to answer this question as precisely as possible. Certain differences could eventually lead to new therapies.

• Blueprints of Disease: Precision Platforms for Modelling Breast Cancer Research output

  Breast cancer (BC) is a clinically and biologically heterogeneous disease.

• Pulling the strings on anti-cancer immunity Research output

  Promotores: J. Jonkers, K.E. de Visser

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  Bart de Leeuw Student Assistent

  Faculty of Humanities

• Classical conditioning to improve immunotherapy in cancer Research project

  Can the conditioning paradigm be used for checkpoint inhibition cancer treatment?