Research and design are two activities that are becoming increasingly important in the Dutch subjects O&O (‘research and design’) and NLT ('nature, life and technology’). The dissertation of Tessa Vossen (ICLON and Faculty of Science) indicates that teachers and students understand the importance of…

Leiden has a long history in the treatment of blood cell cancer. Research to find better therapies never stands still. One of the potential treatments currently being worked on is a ‘living medicine’.

The research in this thesis is focused on tomographic reconstruction based on two imaging modalities in electron microscopy.

Promotor: R.C.M. Pelger Co-Promotor: G. van der Pluijm

How can we broaden youth participation in STEM Learning

This dissertation contains the further development of a method for linguistic-stylistic research, which provides a systematic means to interpret global impressions of a text through choices in formulation at word- and sentence level.

Treatment with special stem cells seems to be a good option for suppressing the immune system in organ transplants. Researchers are trying to learn from processes that take place in the human body during pregnancy.

What is life like after a stem cell transplant? Haematologist Jennifer Tjon and nurse practitioner Kyra Oosterink from the LUMC are studying how patients experience recovery and what support they need.

My PhD thesis investigates the ecological significance of resistance against drought-induced air bubble formation inside the water conduits of plants (embolism), and the plasticity and functional aspects of stem anatomical traits in woody and herbaceous species.

This dissertation focuses on the systematic vowel alternations displayed by the Proto-Germanic n-stems. The fact is, that many of these nouns now appear to have preserved the ablaut system of the Indo-European proto-language spoken some five millennia ago. In this respect, the n-stems are truly comparable…

The Leiden University Medical Center (LUMC), the Danstem Institute from the University of Copenhagen and the Murdoch Children’s Research Institute in Melbourne have received 300m euros from the Novo Nordisk foundation. The aim of this new international consortium is to bring stem-cell based therapies…

Chemist Roxanne Kieltyka has received an ERC Starting Grant of 2 million euros. In her lab, she creates gels that mimic the instructive material that supports cells in our body. With the grant, she aims to make these gels stiff and tough, and to create a bio-printed miniature heart ventricle.

Embryonic stem cells have the remarkable ability to develop into any type of cell. On their way to become for example a liver or a heart cell, they must repeatedly decide between alternative developmental paths. How they make these decisions is largely unknown. An international team of biophysicists…

Three speakers, three fascinating science stories and a well-filled lecture hall. The Niko Tinbergen Lecture had a successful restart on 10 December 2019.

On Wednesday 11 June 2025 Steffie van Gompel successfully defended a doctoral thesis and graduated.

The Leiden University Medical Center (LUMC) will start construction this year of the largest non-profit stem cell and gene therapy facility in the Netherlands, and one of the largest facilities in Europe. NECSTGEN – the Netherlands Center for the Clinical Advancement of Stem Cell and Gene Therapies…

Pericytes, the mural cells of blood microvessels, are important regulators of vascular morphogenesis and function that have been postulated to mechanically control microvascular diameter through as yet unknown mechanisms.

Despite being the object of intense study, embryonic development has been difficult to model due to a number of reasons. First, complex tissues can be comprised of many cell types, of which we probably only know a subset.

Parkinson's disease is the second most common neurodegenerative disease in the world. One of its symptoms is the loss of dopaminergic neurons in the substantia nigra pars compacta.

How can pupils and students learn to get a grip on complex 'swamp situations'? Inaugural lecture in abbreviated form held by prof.dr.ir. Fred Janssen on the acceptance of the post of professor of science education at Leiden University on 19 June 2017.

Researchers from the Leiden University Medical Center (LUMC) have successfully used stem cell gene therapy to treat a baby with the severe congenital immune disorder SCID. An important milestone: it is the first time stem cell gene therapy of Dutch origin has been administered to a patient, and also…

Leiden University Medical Center (LUMC), as a partner in the reNEW consortium, is once again receiving tens of millions of euros for research into new treatments based on stem cells. The collaboration will receive a total of €150 million to develop new therapies in regenerative medicine.

Leiden biophysicist Stefan Semrau was granted an NWO Vidi earlier this month. He will use the grant to study the role of electricity in embryonic development and tissue regeneration.

Research and design are two activities that are becoming increasingly important in the Dutch subjects O&O (‘research and design’) and NLT ('nature, life and technology’). The dissertation of Tessa Vossen (ICLON and Faculty of Science) indicates that teachers and students understand the importance of…

Methods of treatment for chronic illnesses are limited. Doctors and researchers at Leiden University Medical Center (LUMC) and Leiden University are working on new therapies as an alternative for organ transplants. The goal is to cure the illnesses by restoring organs to their original function. Stem…

In this study, the formation of the Tocharian subjunctive is described, its use and meaning are analysed and its origins are investigated.

Other COI publications can be found on Leiden Law Blog, the Leiden Law Methods Portal, and in the drop-down tabs below.

In this project, we will study the genetic and environmental drivers of woodiness and stem lignification at the level of plant‐to‐gene‐to‐molecule.

Promotor: G.R. de Snoo, Co-promotor: H.H. de Iongh, C.J.M. Musters

EcoConnect aims to support non-STEM educators in integrating climate change education (CCE) into their curricula. The project focuses on enhancing students' knowledge, skills, and (emotional) resilience by providing faculty with tools and methods to address climate change topics effectively.​

Regeneration is the ability of an organism to restore damaged or lost tissue with a functional replacement, and without scarring. Many lizards can regenerate their tails.

We study cell-fate decision-making using embryonic stem cells as a model system. Stem cells integrate a large number of cues to direct their development into a great variety of cell types.

Which genes are involved in woodiness and associated traits such as drought tolerance, flowering time, stem elongation, life span, and plant herbivory, and how do these gene regulatory pathways overlap?

How can educators in non-STEM fields integrate Climate Change Education to enhance students’ knowledge, skills, and resilience?

New technology offers many new possibilities for research, such as on dementia. ‘Organ-on-a-chip’ is a new technology in which small bits of organ are grown out of stem cells on a small plastic plate. A small piece of blood vessel, heart or nerve offers many new possibilities for research, such as…

In 2020, Leiden University launched its stimulated interdisciplinary programs, including one focused on regenerative medicine.

The main purpose of this book is to give a description of the Cholón language as represented in the Arte de la lengua cholona (ALC), a colonial grammar written in 1748 by a Franciscan friar, named Pedro de la Mata. The ALC was transcribed by Fray Gerónimo Clota in 1772. This grammar is kept in the British…

A new therapy for the serious Graft-versus-Host disease

PhD defence

‘Regenerative medicine’ explores ways to repair or replace damaged cells, tissues and organs with cell, stem-cell or gene therapy. It can lead to valuable breakthroughs in the treatment of chronic diseases such as diabetes, heart problems and kidney diseases or muscle diseases.

Lifelong learning | “Even though we were spread across five continents, there was a strong sense of connection.”