Leiden’s Institute for History has an exceptionally strong expertise in premodern European history in its global context, with specialists whose interests cover virtually the whole continent.

Many handwritten and illustrated archives contain a wealth of information, but are largely underexplored because they are complex and difficult for computers to decipher. The aim of this project is to develop a digital environment that resolves this challenge and connects heterogeneous archival content…

Source: PLoS ONE, Volume 10, Issue 3 (2015)

The Encyclopedia of Global Human Migration provides a complete exploration of the prominent themes, events, and theoretical underpinnings of the movements of human populations from prehistory to the present day.

The purpose of this study was to investigate the formation and growth kinetics of complexes between proteins and oppositely charged polyelectrolytes.

In the studies described in this study, we introduce a novel ex vivo human skin barrier repair model. To develop this, we removed the upper layer of the skin, the stratum corneum (SC) by a reproducible cyanoacrylate stripping technique.

Source: Br. J. Pharmacol., Volume 172, Issue 3, pp. 940-55 (2015)

Students at Leiden University College (LUC) gain an understanding of journalism ‘from the inside out’ through innovative teaching methods in the courses Multimedia Journalism, Investigative Journalism and Gender, Media and Conflict. By simulating the actual daily tasks of journalists, they are exposed…

LUCITH runs a number of initiatives and programmes. Below you will find a list of initiatives and activities by the Centre for Islamic Thought and History.

This project proposes to connect two discourses highly present in contemporary literary criticism in China, as well as on the world literary scene and academic circles: the discussion on emigration literature and the concept of ‘essayness’ derived mainly from (post)modern Western theories of the ess…

The current resurgence of whooping cough is alarming, and improved pertussis vaccines are thought to offer a solution. Outer membrane vesicle vaccines (omvPV) are potential vaccine candidates, but omvPV-induced humoral responses have not yet been characterized in detail.

More than 30 members of Programme Committees, Faculty Councils and the University Council met online on 27 November with a mission: how can university co-participation work towards a more sustainable university in terms of education, research, and operations? The Leiden University Green Office and the…

The potential of bioneedles to deliver influenza vaccines was investigated.

PAIR stands for ethical publishing and transparency. Below you can read about our commitment to COPE principles, copyright compliance and rigorous peer review ensures the integrity of every article we publish.

Source: Mediators Inflamm (2014)

Mouse models are commonly used to assess the immunogenicity of therapeutic proteins and to investigate the immunological processes leading to antidrug antibodies. The aim of this work was to develop a transgenic (TG) Balb/c mouse model for evaluating the immunogenicity of recombinant human insulin (insulin)…

C.R. Hermans (2012). Facsimile-editie van Noordbrabants Oudheden aangevuld met enkele Archeologische Mengelwerken.

Poly(lactic-co-glycolic acid) (PLGA) particles have been extensively studied as biodegradable delivery system to improve the potency and safety of protein-based vaccines. In this study we analyzed how the size of PLGA particles, and hence their ability to be engulfed by dendritic cells (DC), affects…

Netherton Syndrome (NTS) is a rare genetic skin disease caused by mutations in the serine protease inhibitor Kazal-type 5 gene, which encodes the lympho-epithelial Kazal-type-related inhibitor. NTS patients have a profound impaired skin barrier function. Because SC lipids play a crucial role in the…

We are very happy to welcome you to spend a semester or year studying or doing an internship with us at the Leiden University Medical Center. Here you will find information on your course timetables and registration.

Source: J Cheminform, Volume 6, Issue 1 (2014)

SMR can be used to measure the mass of adsorbed protein to nanoparticles with a high precision in the presence of free protein.

Fitness is more than physical health alone. An equally important aspect of our general well-being is mental fitness. Mental fitness refers to the fitness of the mind. During your PhD research, there might be periods in which you feel insecure or down. It is essential to take good care of yourself. Don’t…

What is the environmental impact of different waste collection systems across Europe? How can the collection be improved when considering collection, sorting, and treatment, as well as use options for secondary materials?

To reach a larger audience beyond the academy, a number of activities in the cultural realm have been programmed over the years.

Get on your bike… or your tandem, unicycle, electric bike, tricycle, penny-farthing, rickshaw or road bike! We’re going on a bike trip!

Microneedle-based vaccination has several advantages over vaccination by using conventional hypodermic needles.

Source: J Cheminform, Volume 7, Issue 1 (2015)

In higher education, Open Educational Resources (OER) are available for anyone to use, but they are not widely used.

Microneedles represent promising tools for delivery of drugs to the skin. However, before these microneedles can be used in clinical practice, it is essential to understand the process of skin penetration by these microneedles.

This article 'Shaping the European External Action Service and its post-Lisbon crisis management structures: an assessment of the EU High Representatives’ political leadership' assesses the role, influence and core aspects of the EU High Representatives’ (HR/VPs) “political leadership” in the context…

Source: Eur J Med Chem (2015)

What tools can be applied to measure the output, outcome and impact of science communication efficiently and effectively?

Our in-house human skin equivalents contain all stratum corneum (SC) barrier lipid classes, but have a reduced level of free fatty acids (FAs), of which a part is mono-unsaturated. These differences lead to an altered SC lipid organization and thereby a reduced barrier function compared to human skin.…

Each year, Leiden Law Academy welcomes over 2500 course participants. Outstanding lecturers and renowned specialists from the professional field provide legal courses and training.

Source: Biosens Bioelectron, Volume 74, pp. 233-42 (2015)

The 11th edition of Leiden Museum Night will take place on Saturday 18 May 2019. Nine museums will once again be opening their doors. As it is Leiden University’s 444th anniversary this year, we will be celebrating in style at the Academic Historical Museum.

The principal aim of this research is to explore the confrontation between voice and electronics. These are often seen as being radically different from one another and many characteristics seem to be in opposition between them. However, they also have characteristics in common and they can influence…

The barrier function of the skin is primarily provided by the stratum corneum (SC), the outermost layer of the skin. Skin barrier impairment is thought to be a primary factor in the pathogenesis of atopic eczema (AE).

This book contextualizes the use of terror as part of wider movements of political contention, demonstrating that terroristic innovation occurs as part of wider historical processes rather than in a vacuum.

As a former (PhD) student of the Faculty of Archaeology, your relationship with the Faculty doesn’t end when you graduate. You will join an international community of Archaeology Alumni, working in a wide range of careers including academia, commercial archaeology, heritage policy, museums, the media,…

Refugees’ effect on domestic terrorism is conditioned by host-country social perception (attitude about living next-door to foreigners) and economic competition. These hypotheses are tested cross-nationally from 1995-2014 leveraging data from the World Values Survey.

Atopic dermatitis (AD) is a common inflammatory skin disorder characterised by various epidermal alterations. Filaggrin (FLG) mutations are a major predisposing factor for AD and much research has been focused on the FLG protein.

The portal for prospective Indonesian Students contains information about the possibilities to study at Leiden University in the Netherlands.

The skin barrier function is provided by the stratum corneum (SC). The lipids in the SC are composed of three lipid classes: ceramides (CERs), cholesterol (CHOL) and free fatty acids (FFAs) which form two crystalline lamellar structures. In the present study, we investigate the effect of CER chain length…

Clinical psychology is a discipline concerned with the application of psychological science to the assessment and treatment of mental disorders.

Watch the Sustainable Career Event back!

Here we explain how to apply for an elective course in uSis.