1,893 search results for “cancer research” in the Public website
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Collaborative and effective drug development
There are many complex links in the chain that provides patients with new drugs: from fundamental science, to clinical tests, to production. The entire chain can be found in Leiden. Leiden University, the Leiden University Medical Center (LUMC) and the businesses at the Leiden Bio Science Park (LBSP)…
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Overview
Our research is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.
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Stromal immunobiology in gastrointestinal cancer
PhD defence
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EGFR inhibitors in colorectal cancer
PhD defence
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Tumours can use ‘remote control’ to attract blood vessels
Researchers at Leiden University have demonstrated that tumours can apply mechanical means to attract the blood vessels they need to be able to grow. The team published this discovery on 2 March in Nature Scientific Reports.
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Computational modeling of tumor growth and metastasis and the role of the immune system in tumor destruction
In this project, we aim to obtain a quantitative understanding of the role of the immune system in tumor regression, of the role of tumor cell heterogeneity in cancer growth and of tumor cell migration properties.
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Bio-organic Synthesis
The research in the Biosyn group is focused on the design, synthesis and function of the four major types of biomolecules: nucleic acids, carbohydrates, peptides and lipids and hybrid structures thereof. These biomolecules and their derivatives are used in drug discovery and chemical biology, to develop…
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Mathematics-based strategies for repairing tumour blood vessels
How does the extracellular matrix coordinate endothelial cell behavior during angiogenesis, and how do metabolic waste-products and matrix-degrading enzymes produced by the tumour modify the extracellular matrix so as the change the cellular coordination?
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Topic: The placebo and nocebo effects of communication
We study how communication can heal and harm when patients are confronted with an illness. Most of our studies focus on serious illnesses such as advanced cancer. Communication lies at the heart of medicine, yet we do not always know which specific communication helps patients. Moreover, many complaints…
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Anticancer compounds from actinomycetes
How can we find novel natural products from Actinomycetes that act as growth modulators on mammalian cells? Can we harvest and develop the potential of these novel compounds for industrial and medical biotechnology?
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Institute of Biology
Nature is a never-ending source of inspiration for the researchers at the Institute of Biology Leiden (IBL). Based on a better fundamental understanding of nature, they are able to seek solutions in the area of health and biodiversity. The theme of IBL is ‘Harnessing biodiversity for health.’
- Leiden Institute of Chemistry
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Prediction of contralateral breast cancer - Statistical aspects and performance assessment
PhD defence
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Glycoproteomics assays for prostate cancer biomarker discovery
PhD defence
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Development of kinase inhibitors and activity-based probes
Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt
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evaluations of nanocarriers to improve the effectiveness of colorectal cancer treatment
PhD defence
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Bioactive Molecules in Animal Sciences
Animal Sciences’ contribution to the Bioactive Molecules research theme includes research on molecules from natural sources, such as plants, insects, and snake venom, with the aim to identify novel anti-cancer, anti-inflammatory, anti-microbial, and anti-diabetic agents.
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Participants
The CIGR comprises research groups from the Institute of Biology Leiden (IBL), the Leiden Institute of Chemistry (LIC), the Leiden Academic Centre for Drug Research (LACDR) and the Leiden Institue of Physics (LION).
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Targeting SUMO Signaling to Wrestle Cancer
PhD defence
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Peter Bouwman
Science
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The path to individualised breast cancer screening
PhD defence
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Tailored treatment for colon and rectal cancer
PhD defence
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Monitoring Outcomes In Colorectal Cancer Surgery
PhD defence
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Raman Spectroscopy in Bladder Cancer Diagnosis
PhD defence
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Formulation of Peptide-Based Cancer Vaccines
PhD defence
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Lateral Lymph Nodes in Rectal Cancer
PhD defence
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Harnessing neoantigens for targeted cancer treatment
PhD defence
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Identification of regulators of cancer - immune interactions
PhD defence
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Experimental optical imaging during pancreatic cancer interventions
PhD defence
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Dissecting the immune microenvironment of breast cancer
PhD defence
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Genetic and lifestyle factors in breast cancer prognostication
PhD defence
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Coen Wirtz
Faculteit der Sociale Wetenschappen
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Carolien Rieffe
Faculteit der Sociale Wetenschappen
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Arash Pourebrahimi Andouhjerdi
Faculty Governance and Global Affairs
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Gieneke Teeuwen
Faculteit Rechtsgeleerdheid
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Fenneke Sysling
Faculty of Humanities
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Lisa Schreuders
Faculteit der Sociale Wetenschappen
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Haye Geukes
Science
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David Heyne
Faculteit der Sociale Wetenschappen
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Min Cho
Faculty Governance and Global Affairs
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Katy Wolstencroft
Science
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Lucy Opoka
Faculteit Rechtsgeleerdheid
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Camille Lefebvre
Faculteit Rechtsgeleerdheid
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Eva Sievers
Science
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Joram van Ketel
Faculteit Rechtsgeleerdheid
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Marieke Liem
Faculty Governance and Global Affairs
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Kees Verduin
Faculteit der Sociale Wetenschappen
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Experimental Systems: Future Knowledge in Artistic Research
The experimental approach of science applied to artistic research
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Fluorescence Polarization Activity-Based Protein Profiling on Retaining Glycosidases
Glycosidases are important enzymes in the turnover of polysaccharides and glycoconjugates, and are involved in a range of human pathologies including genetic disorders such as Gaucher and Pompe disease, but also in various cancers.
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Research
Research is meant to generate knowledge, in a rational and sensible way. Many research methods exist to do this, and creativity is an important factor. Our mission is to explore creative, playful, unexpected, and unconventional forms of academic research.