The Effects of the 1881 Liquor Act on the Leiden Alcohol Trade

Self-censorship violates principles of a free society but few people want to take the role of the martyr.

Agriculture is among the most vulnerable sectors to climate change and poorer countries face the most severe difficulties. Coffee farmers in Central America, for instance, are facing multiple and mutually reinforcing crises, including price shocks, outbreaks of pests and diseases, migration, and farm…

This thesis describes how different colours of light affect various aspects of the growth and development of Arabidopsis and tomato plants⁠.

This thesis investigates a pharmacological challenge model induced by Toll-like receptor 7 (TLR7) activation, focusing on skin inflammation and its implications for early drug development.

This thesis describes the design, synthesis, and immunological evaluation of varying (neo)antigenic peptide conjugates containing either a TLR2 or a TLR7 agonist.

The objective of this study was to investigate the expression and function of GRHL2 in different breast cancer subtypes.

Brexit has been a kind of shock therapy for the EU and has eventually led to more appreciation for European cooperation. That is what Professor Luuk van Middelaar claimed on 30 November at the conference ‘Brexit and the future of the European Union’ which marked the 60th anniversary of the Europa Institute…

Nature, nurture and neural mechanisms of social emotion regulation in childhood

Many members of the Dutch Royal Family have studied at Leiden University and several have been awarded an honorary doctorate. In 1987, current King Willem-Alexander followed in the academic footsteps of his mother Beatrix, his aunt Margriet and his grandmother Juliana, and started his History studies…

Advanced UHF MRI techniques provide powerful tools for studying the zebrafish brain, an emerging model in neurological research. In this work, various MRI and localized MRS methods are optimized and employed for UHF strength for studying the zebrafish brain.

The main aim of my Ph.D. thesis is to further explore the value of using early developing zebrafish larvae (up to 5 dpf) as a model to study anxiety-like behaviour and their pharmacological modulation with drugs.

Breast cancer is the most common cancer in women worldwide. Metastasis, the process by which cancer cells spread to other parts of the body, makes treatments less effective. It is important to unravel the mechanism of metastasis.

From memorials to the armed forces to memory stones for individual victims. It was only later that the Holocaust took a central role in Western remembrance culture, Cleveringa Professor Frank van Vree notes. ‘Nationalists and human rights activists both invoke the experience of the Holocaust.’

This article provides a comprehensive analysis of the Islamic State's use of images taken by drones, drawing on a dataset of ISIS propaganda images from October 2016 to December 2018.

Young babies laugh like adult apes do: producing sounds while inhaling and exhaling. Adult humans produce sounds on the exhale only. Cognitive psychologist Mariska Kret and colleagues have published an article about the development of human laughter in the journal Biology Letters.

Wouter Moerland is on a two-year secondment as ecology adviser at the Municipality of Leiden. This biology alumnus talks animatedly about his work. ‘We’re working hard to increase nature’s chances in town.’

Contraband and forced recruitment: How rebels' exploitation of natural resources can increase their willingness to forcibly recruit children.

Relevant safety issues are associated with hazardous materials transportation, especially when transport routes cross populated areas. This article for the Journal of Loss Prevention in the Process of Industries analyses a 2015 accident with a freight train in Tilburg, comparing it to the Viareggio…

The function of TLRs in innate immunity has aroused worldwide attention soon after its discovery. Because of the broad functions of TLR2 in innate immunity, the drive for the development of TLR2-targeted vaccines or therapeutic treatments has accelerated in the last decades.

Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez

Does student and teacher gender affect students’ performance and what is the role of gender stereotypes in this relation?

This project is funded by the Dutch Cancer Society. The project will be part of an ongoing research line aimed at identifying mechanisms of cancer therapy resistance and metastasis. In this project, it will be investigated how the Grainyhead family of transcription factors controls therapy response…

PhD defence

Science Magazine has published three back-to-back papers on an important discovery in solid state physics. Leiden physicist Jan Zaanen wrote a Perspective article on the subject in the same issue of 4 March.

What's it like studying abroad? Noor Ismail and Charlot Oltmans share their experiences in videos made in Hhangzhou and Oslo.

Wija Wijayanto and Arum Perwitasari both were Indonesian PhD students at Leiden University, funded by the Leiden-DIKTI Graduate Scholarship Programme. With the help of this scholarship, literally thousands of students travel abroad to write their dissertations. During their research period, Arum and…

Chapter 2 describes a post-synthetic methodology to introduce a fluorescent label in highly lipophilic, Pam3Cys based conjugates.

On the 20th of April, Chams Benoît Bernard successfully defended a doctoral thesis. The Leiden University Centre for Linguistics congratulates Chams on this achievement!

On Saturday 13 October the historical city Leiden was crowded with prospective students visiting the Open Day. They all came to Leiden to orientate themselves towards studying at Leiden University or to ask questions about the content of the bachelor’s programmes. Among them were a lot of international…

What is it like to be old? Many young people cannot really imagine what it is like. For a group of Honours students, however, this question has been answered. They had the chance to wear an age simulation suit during the Bachelor Honours Class ‘Vitality and Ageing’.

What is it like to be a Leiden University student at Campus The Hague? These prospective students found out on the Experience Day of 30 March.

Guiding high school students as a mentor at Pre-University College: what is that like? And what does it all entail? As part of the 20th anniversary of PRE-College Leiden, we asked two experienced PRE-mentors about their job - and what makes their work so meaningful. ‘You really see them grow.’

Junk news sites with unknown names such as Trendnieuws and Viraal Vandaag reach millions of Dutch people thanks to their Facebook pages. Messages from those pages are much more often shared and liked than messages from pages from well-known news media such as De Telegraaf, NOS and NU.nl. This is shown…

Europe’s security suddenly looks uncertain now President Trump has started negotiations with Putin. What does this mean for the Netherlands? What do we need to do?

Leiden Mayor Peter Heijkoop visited the Faculty of Social and Behavioural Sciences and the Faculty of Science on Monday,

One of the main challenges in the development of an effective anti-cancer vaccine is the generation of an adequate and directed cellular immune response.

After studying medicine in Leiden, Diederik Hofstede specialised in plastic surgery. 'I was attracted by its creativity and I enjoy working with my hands.' Cosmetic surgery is just 5% of the work.'

A team of astronomers led by Dutch scientists have directly imaged a giant planet orbiting at a large distance around a sun-like star. Why this planet is so massive, and how it got to be there, is still a mystery. The researchers will publish their findings in the journal Astronomy & Astrophysics.

Leiden University has a new platform. On 19 September Vice-Rector Hester Bijl officially launched the LGBT+ Network.

Having a bachelor, master and Ph.D in chemistry, Elena Sánchez López shifted to a more biological research for her postdoc. All of her studies she did at the University of Alcala, in Spain. Way back in medieval times, this city was the place of birth of Miguel de Cervantes, author of the world famous…

From a lovely blossoming garden in Barcelona, Eduard Fosch Villaronga is talking enthusiastically about his postdoc at Leiden University. Due to the corona lockdown, he is currently spending the 2020 summer at his mother’s place, but he is looking forward to returning to Leiden (and to the Dutch bit…

Professor of Human Genetics Willeke van Roon will give her inaugural lecture on Monday 28 March entitled: ‘Translational research, where small parts make the bigger picture.’ She will emphasise how university medical centres should take responsibility for finding treatments for very rare diseases.

How can we improve the everyday sounds of the city? In his inaugural lecture on 28 November Marcel Cobussen, Professor of Auditory Culture, advocates using the expertise of sound artists to raise the quality of acoustic environments in cities.

One of them turned out to be two thousand years old. And older giant barrel sponges appear to have a faster rate of cell division, unlike us. They produce antibiotics and much, much more. Lina Bayona Maldonado studied how the differences in such factors as age or oceanic depth affect the production…