898 search results for “patients” in the Public website
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Knowledge discovery from patient forums: gaining novel medical insights from patient experiences
Patients share valuable advice and experiences with their peers in online patient discussion groups.
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Criteria for recovery from eating disorder patients: a comparison between therapists, patients and a healthy control group
Which criteria do ED patients and therapists evaluate as most relevant for recovery? Do patients and therapists differ in their evaluations? Do eating disorder patients differ from a healthy control group in their scores on the Recovery Scale?
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Knowledge Discovery and Data Mining from patient experience repositories
This project develops a scientific method to extract clinically relevant new information from patient forum websites that discuss patient experiences concerning e.g. medication, nutrition, co-morbidities, genetic factors etc.
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Topic: Stigmatization in patients with chronic health conditions
Imagine that you have a chronic skin condition, characterized by red patches of itchy, scaly skin. You regularly notice people staring at your skin and sense their reluctance to shake your hand. Or imagine that you have Parkinson's Disease, causing your hands to tremble and making it difficult for you…
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impulsivity in relation to emotional stress in patients with Borderline Personality Disorder and patients with Attention Deficit Hyperactivity Disorder
How does stress affect different components of behavioral impulsivity and aggression in patients with Borderline Personality Disorder compared to clinical controls (patients with Attention Deficit Hyperactivity Disorder) and healthy controls?
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PROPER: ‘Near-patient’ prostate cancer models for the assessment of disease prognosis and therapy
How to identify patients at risk of developing devastating, metastatic disease and facilitate the development of personalised treatment for prostate cancer patients?
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Optimization of Patient Flow through EMT Facilities Applying Dynamic Behavioral Simulation Models
This study aims to explore the use of a behavioral-design-based approach in simulating patient flow through EMTs. It provides a dynamic behavioral simulation model to assess the interactions between patients, staff members, and the related dynamic movements/interactions with the health care facility,…
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Skin Barrier Lipid Composition and Organization in Netherton Syndrome Patients
Netherton Syndrome (NTS) is a rare genetic skin disease caused by mutations in the serine protease inhibitor Kazal-type 5 gene, which encodes the lympho-epithelial Kazal-type-related inhibitor. NTS patients have a profound impaired skin barrier function. Because SC lipids play a crucial role in the…
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e-Coach: Tailored cognitive-behavioral e-Health care for patients with chronic somatic conditions
The major aim is to develop, evaluate, and implement disease-generic cognitive-behavioral interventions through the internet in order to optimize tailored health care for patients with chronic somatic conditions.
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A three-step approach to supporting patient self-management in clinical practice
The aim of this project is to develop, evaluate, and multicentre implement a blended form of cardiac rehabilitation that uses a theory-based approach to guide patients to full self-management.
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of aminoglycosides and glycopeptide antibiotics in (morbidly) obese patients (AMIGO)
Timely, adequate and optimal treatment of infectious diseases is essential for the survival of patients with bacterial infections (Surviving Sepsis campaign).
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the Modular Nature of Word and Sentence Phonology in Chinese Broca's Patients
This book investigates the effects of brain lesions in the left hemisphere, specifically Broca's area, on the production and perception of vowels, of word tones and of the linguistic use of sentence melody.
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Experiences with the Liverpool care pathway for the dying patient in nursing home residents
The Liverpool care pathway for the dying patient (LCP) is a multidisciplinary tool developed for the dying phase for use in palliative care settings. The literature reports divergent experiences with its application in a nursing home setting related to its implementation and staff competencies. The…
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A novel biofilm for skin barrier repair of patients with atopic eczema
Atopic eczema is a skin disease with increasing incidence currently affecting 25% of the paediatric population. In atopic eczema the skin barrier function is reduced. This barrier is formed by the outermost layer of the skin called the stratum corneum (SC). The SC consists of terminally differentiated…
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Biomarkers for the response to immunotherapy in patients with non- small cell lung cancer
PhD defence
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Concepts and applications for evidence-based dosing in morbidly obese patients before and after weight loss surgery
Promotor: C.A.J. Knibbe, Co-promotores: H.P.A. van Dongen, B. van Ramshorst
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and tools for the exchange, analysis and communication of anonymised patient data
This project is a collaboration between Sanquin, LUMC and LIACS. It focuses on the development of meta-modelling methods and tools for the exchange, analysis, and publication of anonymised patient data. Measures are being constructed to evaluate both the level of privacy and the extent to which an anonymized…
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Reality training tool for optimizing expectancy effects in patient-provider interaction.
We aim to create an innovative e-learning and virtual reality training that helps healthcare providers to optimize placebo effects and minimizes nocebo effects via their communication.
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plays an important role in the skin barrier function of atopic eczema patients
The barrier function of the skin is primarily provided by the stratum corneum (SC), the outermost layer of the skin. Skin barrier impairment is thought to be a primary factor in the pathogenesis of atopic eczema (AE).
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plays an important role in the skin barrier function of atopic eczema patients
OBJECTIVES: To determine whether the lipid/protein ratio and the total dry SC mass per surface area are related with the skin barrier function of controls and AE patients.
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fatty acid chain length for the skin barrier function in atopic eczema patients
An important feature of atopic eczema (AE) is a decreased skin barrier function. The stratum corneum (SC) lipids - comprised of ceramides (CERs), free fatty acids (FFAs) and cholesterol - fulfill a predominant role in the skin barrier function.
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lipid chain length relates to an impaired skin barrier function in patients with atopic dermatitis
Source: British Journal of Dermatology, Volume 170, Number 6, pp. E18-E19 (2014) ISBN:0007-0963
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reduction correlates with the skin barrier function in atopic eczema patients and inflammation plays a role in the altered epidermal lipid biosynthesis
Source: Journal of Investigative Dermatology, Volume 135, pp. S59-S59 (2015)
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Different medication dosage for morbidly obese patients
PhD research recently completed by pharmacologist Margreke Brill shows that morbidly obese patients should be given a different dosage of the drugs Cefazolin and Midazolam. This could also apply to other drugs such as anti-cancer drugs as well as antibiotics and Margreke Brill is advocating a change…
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Start of a new patient study
Navigation Lab Leiden has launched a study on the effects of the navigation training program we have developed, called Wayfinder. Milan van der Kuil is the main researcher on this project and studies how navigation ability can be improved in patients with acquired brain injury.
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Capitalising on research to benefit patients
Menzo Havenga, CEO of Batavia Biosciences on the Leiden Bio Science Park (LBSP), has a favourite hobbyhorse: the Clinical Development Board. The aim of this board is to make sure that high-impact research results in high-value products that will benefit patients.
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A Rembrandt tour for rehabilitating patients
A group of patients were given a guided tour of the larger than life Rembrandt canvases on University buildings around the Rapenburg canal. This was with the help of students from Present, a volunteer organisation, who pushed their wheelchairs over the bumpy cobblestones. The canvases are on show until…
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New professor wants to improve care for sarcoma patients
Doctors should work with patients with bone and soft-tissue tumours to find the best personal treatment strategy says Prof. Michiel den de Sande. He has developed an app that helps choose the right treatment. Van de Sande was appointed Professor of Orthopaedics with a particular focus on paediatric…
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Therapeutic vaccine boosts survival rate in cervical cancer patients
A therapeutic vaccine against HPV-16 (type 16 human papillomavirus) improves the survival rate in cervical cancer patients. A new study by ISA Pharmaceuticals B.V. (a Leiden-based biotechnology company) and the Leiden University Medical Center (LUMC) shows that this vaccine produces a more robust response…
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Treatment before patients develop rheumatism provides lasting relief
Early treatment benefits patients who have not fully developed rheumatoid arthritis but are in the preliminary stages of the disease. This is what researchers from the Leiden University Medical Centre (LUMC) have reported in The Lancet. Patients in the pre-arthritis stage who were temporarily prescribed…
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International media report on Leiden dosage app for corona patients
Coen van Hasselt's research group quickly produced an app that enables doctors to determine the correct dosage of commonly used medicines for corona patients. Media in the Netherlands and abroad reported on the app.
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Diagnosing patients with the help of statistical physics
Doctors are there to diagnose and treat people. But sometimes a diagnosis can’t be made or doctors differ in opinion. Luckily, Alireza Mashaghi Tabari and his research team have developed a new framework to solve medical diagnostic problems. This framework can also be applied to many other research…
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‘Patient demonstrations are a good tool in medical teaching’
On 7 July 2020 medical lecturer Luuk Willems received his SKO certificate (Senior Teaching Qualification) and may now officially call himself a senior lecturer. The course has meant that he now has clear ideas about what he wants to achieve in his teaching. ‘I want to strengthen my role as a coach and…
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Hanneke HulstFaculteit der Sociale Wetenschappen
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PhD candidate uses AI to search patient forums for unknown side effects
Patients on patient forums share all sorts of things about their illness: from side effects and advice to messages of support. PhD candidate Anne Dirkson uses artificial intelligence (AI) to retrieve this information. ‘Ninety per cent of the side effects weren’t officially registered.’
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Leiden statisticians create app for patients and doctors to calculate cancer survival probabilities
A new app is able to calculate personalised survival probabilities for patients suffering from soft tissue sarcoma. Doctors and patients can use the app to calculate personalised survival probabilities together. Mathematician Anja Rüten-Budde received her doctorate for her research into survival probability…
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First patient in the Netherlands successfully treated with stem cell gene therapy
Researchers from the Leiden University Medical Center (LUMC) have successfully used stem cell gene therapy to treat a baby with the severe congenital immune disorder SCID. An important milestone: it is the first time stem cell gene therapy of Dutch origin has been administered to a patient, and also…
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Headache e-diary aimed at more personalised help for patients and physicians
Funded by a ZonMw grant, the LUMC and the Health Campus The Hague will be working with headache patients on research into the use of an electronic headache diary. This resource can help patients gain a better understanding of their migraine attacks and, together with the physician, produce the best…
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Putting migraine into words: the patient’s account is crucial for diagnosis
Migraine can’t be diagnosed with a blood test, scan or physical examination. Language therefore plays a crucial role in its diagnosis. Neurologist Joost Haan has researched the relationship between language and migraine, and looked at how migraine is described in fiction. His PhD defence is on 22 Oc…
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Care conferences for long-term forensic patients: demand greater than supply
Care conferences for long-term residents (15+ years) in forensic mental health care are widely appreciated by all parties involved. Research by Leiden University shows that the demand for these meetings is so great that the supply cannot be met within the desired time frame.
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Medical Delta professor Lioe-Fee de Geus-Oei: 'We work together for the patient'
Professor of Radiology Lioe-Fee de Geus-Oei was already a professor at LUMC and the University of Twente. As Medical Delta professor, she has now also been appointed at Delft University of Technology. 'Talking with people from other disciplines always makes me immensely humble, because they look at…
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Court case of 15-year-old anorexia patient: force-feed or right to self-determination?
Via expedited proceedings at Leeuwarden Court of Appeal, a mother is trying to impose a relatively new treatment for her 15-year-old daughter’s eating disorder. The girl is suffering from anorexia nervosa and if she does not receive urgent treatment which the girl herself supports, there is a chance…
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Patient to plastic surgeon: ‘I want to look like my selfie.’
An image has great powers of persuasion. It is said that ‘a picture is worth more than a thousand words’. But these days, images can easily be manipulated with severe consequences. ‘Perhaps it’s time to reconsider the value we attach to images’, says Elize de Mul, whose PhD thesis deals with ‘digital…
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Treating Meningioma: does the patient benefit?
PhD defence
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4D Picture project
Helping cancer patients with treatment choices.
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Catherijne KnibbeScience
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Predicting Outcomes in Patients with Kidney Disease
PhD defence
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Measuring symptoms and functioning in glioma patients
PhD defence
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Patient-relevant outcomes after kidney transplantation
PhD defence
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Traffic accident victims and polytrauma patients
PhD defence