What are the biological effects of Chinese herbal medicine in regulation of cancer cell metastasis?

Can we link multiple components from herbal extracts with their biological activities?

Promotor: Prof.dr. E.F. Smets, Co-promotor: T.R. van Andel

The main aim of my Ph.D. thesis is to further explore the value of using early developing zebrafish larvae (up to 5 dpf) as a model to study anxiety-like behaviour and their pharmacological modulation with drugs.

Chair of LU-European Center for Chinese Medicine and Natural Compounds, Institute of Biology, Leiden University - the Netherlands

The Metabolomics Facility of the University of Leiden has brought together two research groups from the Faculty of Science that are well-known for their expertise in two different fields: the Biomedical Metabolomics Facility Leiden, experts in clinical metabolomics and the Natural Products Laboratory,…

Promotor: Jan van der Greef; Co-promotors: Mei Wang; Eduard van Wijk

This study documents and translates the Saa (Zapotec) cultural heritage of the Bene’ Ya’a/En’ne I’ya peoples, the Zapotec inhabitants of the Sierra Norte of Oaxaca.

An international research consortium led by Bob van de Water, Professor of Toxicology at Leiden University, has been awarded a prestigious Horizon2020 grant of 30 million euros.

During orange juice production only around a half of every orange is turned into juice. Lizah van der Aart and Blair Berger, both MSc-students at the IBL, and Ryan Bogaars from Delft University, received an NWO-scholarship to develop a novel method to extract natural products from orange residue.

An international team from the Netherlands, France, Norway and Austria demonstrate how new sequencing technologies can be used to efficiently generate the genome, DNA, sequence of an endangered animal, the European Eel.

Skilful watercolours by botanical painter Esmée Winkel, anatomical flower models and the odd stunning real orchid. In the Extraordinary Orchids exhibition at Oude UB, the Hortus botanicus shows us the wonderful world of the orchid.

What chemicals do plants have available, and what happens if they use them when faced with bacteria or fungi? That is what PhD candidate Luis Salomé Abarca is keen to learn. He studies plants’ survival and their use of chemical components in communication and defence. Salomé Abarca works at the Natural…

An international consortium of research groups is aiming to develop novel antibiotics against the tuberculosis bacteria and two other deadly bacteria. The European Union has awarded a total of 18 million euros to the RespiriTB and RespiriNTM projects. Researchers from the Leiden University Medical Centre…

The Faculty of Science forges new research collaborations with the Institut Teknologi Bandung in Indonesia in the fields of tropical diseases, e.g. tuberculosis and medical biotechnology.

David Versluis successfully simulated an infant gut virtually. This is crucial for research on improvements in formula milk. Currently, such research primarily relies on diaper contents, which is not optimal. Versluis defended his doctoral thesis on April 23.

The first phase of the construction of the new building for the Faculty of Science is finished. The Cell Observatory of the Institute of Biology Leiden will be moving to the new building on the 19th of May.

Edith Schippers, Minister of Health, will be investing six million euros over the coming four years to boost research on new antibiotics. The programme will be set up by several different parties, including the Leiden Centre for Antimicrobial Research.

To develop good cancer treatments, we need to know much more about how malignant tumour cells develop. Professor Ewa Snaar-Jagalska looks at not just the effect of medication on isolated cells but also the behaviour of cancer cells in their tissue environment. Inaugural lecture on 11 December.

Zebrafish-human communication shows that cancer cells lacking a signaling protein are less able to develop aggressive metastatic properties. This discovery has been made by molecular cell biologist Claudia Tulotta. PhD defence 14 June.

The Pilgrims to America exhibition at Museum De Lakenhal inspires reflection. How far do you go in the quest for freedom? It focuses on the Pilgrims’ relationship with the University and which knowledge they took with them from Leiden.

Genes predict whether you have a propensity for an illness but environmental factors often have the last word: nutrition, air pollution, lifestyle, stress. The exposome as both culprit and chance. Large-scale research is being carried out into this at Leiden. Thomas Hankemeier, Professor of Analytical…