2,154 search results for “drug development” in the Public website
-
Combatting antibiotic resistance in a clever way
When you become very good at one thing, that sometimes comes at the expense of something else. Such trade-offs also apply to bacteria. When becoming more resistant to one antibiotic, bacteria can sometimes become more sensitive to another. Linda Aulin, PhD candidate in the pharmacology group of Coen…
-
From stress to success: how actinobacteria exploit life without a cell wall
The central question of this Vici proposal is to investigate if, and how actinobacteria exploit life without a cell wall.
-
Making Environmental Regulation Work for the People
The project’s overall goal is to improve Indonesia’s environmental legal framework and its implementation by strengthening the regulatory capacity of the government, and by enhancing the capacity of CSOs and scholars to hold the government accountable for its regulatory performance.
-
Mathematics-based strategies for repairing tumour blood vessels
How does the extracellular matrix coordinate endothelial cell behavior during angiogenesis, and how do metabolic waste-products and matrix-degrading enzymes produced by the tumour modify the extracellular matrix so as the change the cellular coordination?
-
Promoting Legal Certainty and Increasing Judicial Skills in Selected Areas
How can the legal and socio-legal research skills of Indonesian jurists be increased in order to promote legal certainty and to strengthen the capacity of the judicial training in the country?
-
Willem van der Does sheds new light on the at times pitch-black history of psychiatry
Piercing through the skull with an ice pick, administering electric shocks without an anaesthetic, or applying leeches to the uterus: these may seem like medieval methods of torture, but they are in fact therapies used in medicine. Willem van der Does writes about all of them in his new book. ‘Physicians…
-
Four Leiden University researchers receive Rubicon Grants
Four Leiden researchers, who have recently obtained their PhDs, will receive a Rubicon Grant from NWO to conduct research abroad. A total of 22 scientists have received Rubicon Grants. This grant aims to provide young, promising scientists with international research experience.
-
Four Leiden Science researchers go abroad with Rubicon grant
Astronomer Donggang Wang, physicist Anne Meeussen and chemists Nick Gerrits and Elliot Mock: all four are receiving a Rubicon grant from the Dutch Research Council (NWO). This grant for young talent will enable them to spend two years doing research at a foreign university.
-
Fine Mechanical Department
What is the Fine Mechanical Department?
-
Coronavirus: LUMC media appearances
The staff of the Leiden University Medical Center are doing all they can to help as many corona patients as possible. They are also making regular media appearances to discuss the disease. Below are a few examples.
-
Psychologists participate in high-tech biomarker research in health care
Next generation immunodermatology (NGID) is a nationwide, large-scale project, funded by a large grant of the Dutch NWO to unravel novel biomarkers for six different skin diseases. These biomarkers will drive a high-tech, patient-centric approach in clinical practice. Health psychologist Sylvia van…
-
Seven Leiden researchers win €1.5m Vici grant
Seven Leiden researchers have each been awarded a Vici grant by the Netherlands Organisation for Scientific Research (NWO). This will enable them to form a research group and develop their own innovative line of research.
-
Vidis for nine Leiden researchers
Nine talented Leiden researchers have been awarded a Vidi subsidy by the Netherlands Organisation for Scientific Research (NWO). Vidis are intended for researchers with several years of research experience who want to set up or expand their own line of research.
-
Leiden2022 Life Sciences and Health Week
Conference
-
MicroRNA: so small but so very important
The discovery in 2001 of the importance of microRNAs turned the world of molecular biology upside down. The small particles of RNA also attracted the attention of university lecturer Erno Vreugdenhil. Vreugdenhil: ‘Within five to ten years the first microRNA-directed medicines will come onto the mar…
-
EUFEPS congres
EUFEPS Women in Pharmaceutical Sciences Award for Jara Bouma
-
Erik Danen new Dean of the Graduate School of Science
The Graduate School of Science starts 2024 with a new Dean. The Faculty Council appointed Erik Danen for the coming four years. He succeeds Eric Eliel, who has held the position since May 2020.
-
Study associations sign covenant: limit your alcohol consumption and look after each other
Opting more often for mocktails or soft drinks rather than beer or wine, talking to others about their drinking and pointing out the ban on drugs. Leiden University’s new covenant on alcohol and drugs for study associations encourages providing more alcohol-free alternatives.
-
Cuba
This is an Erasmus+ International Credit Mobility project of Leiden University Medical Centre with University of Havana.
-
Small amounts of sub-visible aggregates enhance the immunogenic potential of monoclonal antibody therapeutics
PURPOSE: Determine the effect of minute quantities of sub-visible aggregates on the in vitro immunogenicity of clinically relevant protein therapeutics.
-
ERC Consolidator Grant for Eveline Crone
Eveline Crone surmises that adolescence also has a positive effect on social development. She believes, for example, that it is in adolescence that young people learn the skills of cooperation, sharing and helpfulness. She will be researching this hypothesis in the coming period with an ERC Consolidator…
-
Cleaning up tuberculosis and salmonella infections
The cellular recycling system in zebrafish is capable of eating harmful bacteria and thus resist infections such as tuberculosis and salmonellosis. That is written by Leiden biologists from the group of Annemarie Meijer. Stimulating this form of defence could be used in new treatment methods against…
-
Double inaugural speech: how social context influences processes in the brain
It’s not a regular occurrence at Leiden University: two professors giving their inaugural lecture on the same day. Berna Güroğlu and Ellen de Bruijn specialise in related disciplines: they both research the influence of social context on processes in the brain – Güroğlu in adolescents and De Bruijn…
-
Superselective bonds light up
Rather than one key and one strong lock, biology often uses tens or hundreds of weaker links to bind parts together, such as cells membranes. This allows for selectivity and also reversibility: the binding can also be undone. Researchers first caught this phenomenon using spheres or colloids, and published…
-
Looking at the person beyond the blood clot
How can we improve the treatment of thrombosis, reduce the disease’s impact and spend less money while we’re at it? This is what Erik Klok, Professor of Internal Medicine and an internist, is researching. He will discuss it in depth in his inaugural lecture on 10 March.
-
Can we live longer? Leiden physicist makes discovery in protective layer in genes
With the aid of physics and a minuscule magnet, researchers have discovered a new structure of telomeric DNA. Telomeres are sometimes seen as the key to living longer. They protect genes from damage but get a bit shorter each time a cell divides. If they become too short, the cell dies. The new discovery…
-
Is Michael Meijer the Smartest Chemist of the Netherlands?
He is occupied with the home stretch of his promotion. But in between, there is another challenge: Michael Meijer is going through to the finals of ‘The Smartest Chemist of the Netherlands’. On Tuesday 9 October, he and five others fight for this title during the Evening of Chemistry. ‘I was dragged…
-
Quantitative Pharmacology Approaches to Inform Treatment Strategies Against Tuberculosis
PhD defence
-
Millions invested in Leiden method of determining sex of chicks before hatching
Discovering whether a chick is male or female while it is still in the egg. Leiden biotech company In Ovo, a spin-off of Leiden University, has been given an investment of several million euros to further develop its unique test method. The founders - both Leiden alumni - Wouter Bruins and Wil Stutterheim…
-
Leiden and Indonesia strengthen ties on sustainable research
Prof. Arnold Tukker, Scientific Director of the Institute of Environmental Sciences Leiden (CML), visited the Center for Sustainable Development Goal Studies (SDGs Center) as part of a trip to Asia. The SDGs Center is a Center of Excellence at Padjadjaran University in Bandung, Indonesia, with which…
-
On this public day on psychedelics, researchers transcend the media hype
Never before has so much research been carried out on the therapeutic effect of psychedelic drugs. Researchers at the LIBC Public Day are happy about the effect the drugs can have on depression, anxiety and PTSS, but at the same time they have some doubts. ‘The hype is bound to crash before long.’
-
17 Leiden researchers on highly cited list
Seventeen Leiden University scientists appear on the 2019 Highly Cited Researchers list, which was announced on 19 November by Clarivate Analytics.
-
Mario van der Stelt and Laura Heitman have been awarded an NWO ECHO-STIP grant
On Friday May 3rd 2013 NWO has announced that Dr. Mario van der Stelt, Division of Bio-Organic Synthesis (LIC) and Dr. Laura Heitman, Division of Medicinal Chemistry (LACDR), have been awarded with an ECHO-STIP grant for their project, entitled: “Novel target engagement biomarkers for better drug ca…
-
New way of driving nanomotors
Leiden Physicists have found evidence for the Berry-force that could be used for driving tiny nanomotors, just like a river drives a water wheel. Nanomotors could be used for drug delivery in the human body. Publication in Beilstein Journal of Nanotechnology.
-
Cannabis makes you less alert
Regular users of cannabis are less aware of their own mistakes, and they are not good at creative thinking. This is the conclusion drawn by psychologist Mikael Kowal from his research on the effects of cannabis. PhD defence 6 October.
-
Johan Kuiper: vaccin tegen aderverkalking
Ontwikkelen van een vaccin tegen aderverkalking
-
Sibel Bahtiri is one of the new Faces of Science: ‘I want to show how we’re finding alternatives to animal testing’
PhD candidate Sibel Bahtiri is one of the new Faces of Science. In videos and blogs, she will show what life is like as a young researcher.
-
Interdisciplinary research and new friends during LACDR Summer School
From the Republic of Moldova to Italy and from Indonesia to Greece, students from all over the world participated in the Bio-Pharmaceutical Science Summer School 2017. The students got a comprehensive overview of the education and research performed within the LACDR. ‘I am very happy to be here,’ says…
- IBL Spotlight - Development & Disease
-
Debate: ‘A Crisis on the Rise? The Impact of Violence and Impunity on Mexican Society’
Mexico is currently facing an unprecedented social and political crisis, with expanding criminal and political violence, rampant impunity and crumbling political institutions. Next to the daily report of anonymous victims of violence, last summer in Central Mexico at least 15 citizens were executed…
-
Environmental and genetic drivers of wood and lignin formation in flowering plants
In this project, we will study the genetic and environmental drivers of woodiness and stem lignification at the level of plant‐to‐gene‐to‐molecule.
-
New insights into mycobacterial infections with NWO grant
Why are mycobacteria such successful pathogens? And are there defence mechanisms in the body that help reduce an infection? To find out, Annemarie Meijer has been awarded the NWO Open Competition ENW-XL grant. She will not explore this quest alone. Five other leading Dutch research groups are participating…
-
Targeting gun violence & trafficking in Europe
To assess the impact of illicit firearms trafficking on gun violence, this research looks at the scope, characteristics and contexts of firearm violence, and also the scope and nature of firearms trafficking in Europe since the new millennium. Nils Duquet, Dennis Vanden Auweele and Marieke Liem created…
-
A History of Dutch Corruption and Public Morality (1648-1940)
A History of Dutch Corruption and Morality showcases 300 years of change, continuity, and diversity in the history of Dutch political corruption and public morality. It analyses a series of corruption scandals and shows how the following debates were connected to the big changes of that time: from the…
-
Memory boost: A novelty-exposure intervention to counteract memory decline.
This project aims to identify which aspects of exploring a novel environment produce beneficial effects on memory. The effects of novelty will be investigated across the lifespan, including children, adolescents and older adults.
-
Working at the Faculty of Science
Working for a top faculty? Discover the vacancies at the Faculty of Science and apply immediately.
-
Research
Through metabolism, biochemical processes give rise to the complexity of life. Acquired and inborn errors in metabolism underlie many diseases occurring in man. The challenge for present day medical biochemistry is to find, and integrate, pieces of information at molecular, cell and organismal level…
-
Minors
The minors offered by the Faculty of Governance and Global Affairs in The Hague are closely linked to the defining image of The Hague as a city of international justice, peace and security as well as the centre of Dutch public administration and international governance.
-
LEAF
Leiden University encourages all its laboratories to obtain LEAF (Laboratory Efficiency Assessment Framework) accreditation.
-
Influencing your health with your behaviour and thoughts
Psychological processes have a major effect on the course of a disease and the effects of medical treatment. Researchers in the field of Psychoneurobiology examine the interactions between body and mind. They investigate the effects of stress as well as the effect of placebos and nocebos, which can…