1,682 search results for “drug development” in the Public website
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Arnout Koornneef
Faculteit der Sociale Wetenschappen
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Sensing Transport
Solute carrier (SLC) transporters are a large and diverse class of relatively understudied transmembrane proteins.
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Research projects
An overview of research projects at the Predictive Pharmacology group.
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Peer feedback in teacher professional development
This dissertation set out to provide both an integrated framework for the practices of teacher peer feedback and an in-depth understanding of teacher peer feedback in the Chinese vocational education context.
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Vision and Mission
The need for novel drugs as well as innovations in their development and application is as urgent as ever. Below we present our vision , mission, and our key research areas.
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Skin researcher calls for multidisciplinary collaboration: ‘I want to pool expertise’
In dermatology, there should be a high level of multidisciplinary collaboration among institutes and specialists, Professor of Translational Dermatology, Robert Rissmann, will say in his inaugural lecture on 8 July. He is building an infrastructure that will put pre-clinical and clinical skin research…
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Using AI to improve the Design-Make-Test cycle with Galapagos
Researchers at LED3 are working together with biopharmaceutical company Galapagos to develop software for use in early drug discovery (funded by NWO). This software is able to design molecules with several simultaneously optimized characteristics and will also take prediction reliability into consideration…
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Modeling interactions to unravel biomarkers for disease progression and treatment response
The aim of this project is to explore the use of statistical interaction models to quantify cross-omics and omics-drug interactions in large-scale clinical and experimental datasets
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NeCEN
With the powerful electron microscopes at NeCEN we study abnormalities in cells of blood vessels in cardiovascular disease, the interaction between pathogens and hosts in infectious diseases, molecular processes that cause cancer and the interaction between drugs and target proteins. Drug development…
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Hit and Lead Optimization
The goal of hit and lead optimization is to optimize suitable chemical starting points that can modulate a drug target. The methods and technologies used are similar to those in Hit Discovery, but once the compound has shown activity in an animal model, it moves from 'hit' to 'lead.'
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Mario van der Stelt
Science
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Roxanne Kieltyka
Science
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Gerard van Westen
Science
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Madeline Kavanagh
Science
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comprehensive understanding of (facilitating) teacher professional development
What are ‘missing links’ in research on teacher professional development trajectories? We focus on the role and development of teacher facilitators in designing and implementing (collaborative) professional development trajectories.
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Foreign capital and colonial development in Indonesia
The proposed research program studies the impact of private foreign investment on development in Indonesia during the years c. 1910-1960.
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Finding and valorizing new antibiotics using AI
Antibiotics are a class of medicine most people take for granted. But pathogenic bacteria are becoming more and more resistant to our antibiotics, and this poses a great challenge for future treatments. There is thus a great societal need to identify new molecules that can address new targets and be…
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Andrea Spruijt
Faculteit der Sociale Wetenschappen
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David Zetland
Faculty Governance and Global Affairs
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Zijian Li
Faculteit der Sociale Wetenschappen
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Inge van der Weijden
Faculteit der Sociale Wetenschappen
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Maria Gabriela Palacio Ludeña
Faculty of Humanities
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Marieke Bos
Faculteit der Sociale Wetenschappen
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Kiki Spaninks
Science
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Evelien Urbanus
Faculteit der Sociale Wetenschappen
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Christine Mummery
Faculteit Geneeskunde
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Tommy van Avermaete
Universitaire Bibliotheken Leiden
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Sheila van Berkel
Faculteit der Sociale Wetenschappen
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Anar Ahmadov
Faculty Governance and Global Affairs
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Barbara Gravendeel
Science
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Jimena Pacheco Miranda
Faculteit der Sociale Wetenschappen
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Shannon Yuen
Faculteit der Sociale Wetenschappen
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George Miley
Science
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Marja Oudega
Faculteit der Sociale Wetenschappen
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Jennifer Anderson
Science
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Liza van den Bosch
Faculteit der Sociale Wetenschappen
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Tales Yamamoto
Science
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Ili Ma
Faculteit der Sociale Wetenschappen
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Nienke Wieringa
ICLON
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Leiden Institute of Chemistry
The chemical industry must continue to innovate for a more sustainable, healthier society. The reseachers from the Leiden Institute of Chemistry (LIC) contribute by applying their knowledge to themes such as sustainability, energy and health.
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Gene regulation in embryonic development
The human body consists of hundreds, perhaps thousands of different types of cells, each with different morphologies and functions, despite having the same genome.
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Genetic risk & atypical development: 22q11 Syndrome
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Regulation of vegetative development and life history strategy in plants
How is vegetative development regulated in plants and how does this affect a plant’s life history strategy?
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Mycobacterial cell wall-deficiency and its role in the persistence of tuberculosis
What is the role of cell wall-deficiency in the persistence of tuberculosis?
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Developing metabolomics for a systems biology approach to understand Parkinson's disease
Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…
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Translational Immuno-Pharmacology
The Translational Immuno-Pharmacology group works on translating the efficacy of anti-infective therapy from preclinical (e.g. in vivo) to clinical, and is led by Rob van Wijk. Infectious diseases, such as tuberculosis, are in constant need of new therapies that work better, faster, and with less risk…
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Staphylomics: Identifying host factors involved in staphylococcal infection
How can Staphylococcus aureus bacteria subvert the host immune system?
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Quantum optics for asylum seekers
The Clinical Epidemiology department at the LUMC has set up a series of lectures for asylum seekers. The series has become a huge success.
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Novel receptor concepts
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Smartmix: A new generation of efficient biomedical research
Can we find and commercialise new treatments for chronic disease that affect our ageing population? And how can we customise this research and development programme to the small but highly-developed Netherlands research economy?