1,099 search results for “brain function and dysfunction” in the Public website
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New ecological maps show a wider range of functional diversity
Together with a large international team of scientists, researchers Peter van Bodegom and Nadia Soudzilovskaia of the Leiden Institute of Environmental Sciences (CML) have created maps of variability in plant trait distribution across the globe. The new maps have been published in Proceedings of the…
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Organisation
The programme group Forensic Family and Youth Care Studies is one of the six programme groups within the department of Child and Education Studies at Leiden University.
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Zeta-values of arithmetic schemes at negative integers and Weil-étale cohomology
This work is dedicated to interpreting in cohomological terms the special values of zeta functions of arithmetic schemes.
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Pressure on function of checks and balances in Parliament
Polls conducted by I&O research point to a political landslide. What's in store for the Netherlands? The polls show that the new party of MP Pieter Omtzigt is well-positioned for the upcoming election, with an expected 31 seats, but only 3 for the Christian Democratic Alliance (CDA) party. It is obvious…
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Towards a “New” Sonic Ecology
How can we let the sonic speak in public urban environments? What is the function and position of sound in our daily encounters with urbanity? How do we experience cities aurally? This was the topic of Marcel Cobussen's inaugural lecture on November 28th, 2016.
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A computational study of structural and excitonic properties of chlorosomes
The long-held desire - to link structure directly to function and to explain molecular mechanisms based on basic chemical or physical principles - is finally coming closer, satisfying not only our scientific curiosity but also offering new solutions to the many challenges in the field of health, energy…
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Kiki Zanolie
Faculteit der Sociale Wetenschappen
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Anna van Duijvenvoorde
Faculteit der Sociale Wetenschappen
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Hongchang Shan
Science
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Serge Rombouts
Faculteit der Sociale Wetenschappen
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Michelle Achterberg
Faculteit der Sociale Wetenschappen
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Lina van Drunen
Faculteit der Sociale Wetenschappen
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Provincial council election results prove democracy is functioning well
Voters sent a clear signal in the recent Dutch provincial council elections with the 'monster' victory for the Farmer-Citizen Movement (BoerBurgerBeweging, BBB). This sign of ‘social resistance’ has consequences for the policy on nitrogen emissions, according to Geerten Boogaard, Professor of Local…
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Jeshua Tromp
Faculteit der Sociale Wetenschappen
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Wilma Resing
Faculteit der Sociale Wetenschappen
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Jörg Meyer
Science
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Global distribution patterns of mycorrhizal associations
Mycorrhizas are symbiotic associations between soil fungi and most plant species.
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Sex, quality of life and brain function in Complex Regional Pain Syndrome
PhD defence
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Influence of Central Neuraxial blockade on anesthetic pharmacology and brain function
PhD defence
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After graduation
Psychology graduates acquire skills useful in a variety of jobs. Whether helping people with mental disorders, researching the brain or deciding who should be hired at a company, psychologists can do it.
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Interstellar Catalysts and the PAH universe
Organic molecules in interstellar space are important as they influence the structure of galaxies and star formations. Studying catalytic processes in space allows us to understand how molecular species are formed and chemically evolved in the interstellar medium and solar system objects.
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Towards a system-based pharmacology approach to predict developmental changes in renal drug clearance in children
Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)
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Rebel with a cause: The effects of leadership encouragement and psychological safety on professionals' prosocial rulebreaking behaviour
This article examines leadership encouragement and psychological safety as antecedents of prosocial rule-breaking (PSRB) behaviour.
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Systems dermatology of immune-mediated dermatological diseases: cutaneous T-cell lymphoma
The complex pathophysiology of immuno-dermatological disorders is multifactorial, including environmental, skin microbiome, (epi)genetic and immune dysregulation conditions. This project primarily focuses on the orphan disease mycosis fungoides, a subtype of cutaneous T-cell lymphoma. The current pathophysiological…
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Omics data integration with genome-scale modelling of dopaminergic neuronal metabolism
Parkinson's disease is the second most common neurodegenerative disease in the world. One of its symptoms is the loss of dopaminergic neurons in the substantia nigra pars compacta.
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The Role of Linker DNA in Chromatin Fibers
The genetic information of all living organisms is contained in their DNA. Cells modify the degree of DNA compaction by epigenetics, which largely determines what genes are read out and which genes are transcriptionally silent.
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Dietsje Jolles
Faculteit der Sociale Wetenschappen
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Anne Hafkemeijer
Faculteit der Sociale Wetenschappen
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Highly Accurate Simulations and Benchmarking of Molecule-Surface Reactions
Heterogeneous catalyzed processes are highly significant to the chemical industry. Dissociative chemisorption (DC) of molecules on surfaces is always considered as a step with a high degree of rate control for heterogeneous catalysis.
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Computational electrocatalysis
This dissertation focused on computational methods based on first principles calculations using the Density Functional Theory (DFT) framework. Emphasis was laid on affordable methods that can provide a tradeoff between computational expense and accuracy.
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Peter van Bodegom
Science
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Thomas Hansen
Science
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Force sensing and transmission in human induced pluripotent stem-cell-derived pericytes
Pericytes, the mural cells of blood microvessels, are important regulators of vascular morphogenesis and function that have been postulated to mechanically control microvascular diameter through as yet unknown mechanisms.
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Updated MRI scanner ready for use
The updated MRI scanner at the Leiden Institute for Brain and Cognition (LIBC) will become operational on 29 September. The new version is faster and better than the current model.
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Predicting dementia
In the future, physicians may be able to identify dementia much earlier than they can today because a computer algorithm will be able to predict from brain scans how our memory is going to develop.
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Law and Governance in Muslim Societies
With regard to governance, policies and law, many Muslims and Muslim countries recognise the possibility that Islam has something important to say about the way society is to be ordered, governed, and regulated.
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GRIPonMASH
GRIPonMASH will address the unmet public health need of reducing disease burden and comorbidities associated with Metabolic dysfunction-Associated Steatotic Liver Disease (MASLD).
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Psychosomatic Imagery. Photographic Reflections on Mental Disorders
Introduces a novel trope of photographic images dealing with states of mental disorders; focuses on photographs that visualize disturbed corporeal and mental perceptions of the world and connects medium-specific characteristics of photography to concepts from mental disorder studies.
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Intercellular Skin Barrier Lipid Composition and Organization in Netherton Syndrome Patients
Netherton Syndrome (NTS) is a rare genetic skin disease caused by mutations in the serine protease inhibitor Kazal-type 5 gene, which encodes the lympho-epithelial Kazal-type-related inhibitor. NTS patients have a profound impaired skin barrier function. Because SC lipids play a crucial role in the…
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Eveline Crone wins Dr Hendrik Muller prize
Eveline Crone, professor of neurocognitive developmental psychology at Leiden University, has been awarded the Dr Hendrik Muller Prize for Behavioural and Social Sciences by KNAW.
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Developmental and Educational Psychology Lab
What is the relation between brain development and social and cognitive development across childhood, adolescence and adulthood?
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Pharmacological resting-state fMRI in aging and dementia
How can we implement the technique of pharmacological resting-state fMRI to improve the diagnosis of dementia?
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Monitoring drought and salinity stress in agriculture by remote sensing for a sustainable future
Food security is challenged by a growing global population and by climate change. Drought and soil salinity are considered the most important ones that inhibit crop yield and distribution. Worryingly, climate change is predicted to increase not only their frequency and severity, but also their co-occurrence,…
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Surface Temperature and the Dynamics of H2 on Cu(111)
Heterogeneous catalysis is one of the fundamental processes of modern life, being common in industrial refinery and hydrogen vehicles, all the way to the living cell. The dissociation of H2 on Cu(111) is an important benchmark system for studying heterogeneous catalysis, with a large and varied amount…
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ACPA alumnus Clarence Charles on functions of calypso music as a cultural expression
Charles wrote an article 'Assimilating Afro Caribbean Carnivalesque Culture' for the publication 'Understanding América. The essential contribution of Afro-American music to the sociocultural meaning of the continent'
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EEG Lab
Psycholinguistic research
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Training children in self-control
What is the effect of training children to exercise self-control? Niko Steinbeis has been awarded a major European subsidy to find the answer to this question. The innovative aspects of this research are the target group, an individual approach to the training and examining the child brain the scann…
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Density functional theory is an accurate predictor for variation with geometry of barriers for reactions on metals
A semi-empirical version of the specific reaction parameter approach to density functional theory (SRP-DFT) has been remarkably successful at predicting dissociative chemisorption probability vs. incidence energy curves for reactions on metal surfaces. New quantum Monte Carlo (QMC) calculations on the…
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Charge transport properties of Ru-complex molecules: the influence of humidity
I will give a general introduction to the field of molecular electronics, its history, methods and challenges. I will also introduce the subject of my investigation and provide a brief outlook to the remainder of our thesis.
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Better reading comprehension
How can we help children and adults to acquire better reading comprehension? Paul van den Broek and his colleagues at the Brain and Education Lab are searching for an answer to this question by investigating reading and the related brain activity.