786 search results for “antibiotic resistance” in the Public website
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Thiosugars: reactivity, methodology and applications
Carbohydrates, alongside proteins and nucleic acids, constitute a crucial and versatile family of biomolecules present in all life forms. They manifest as monosaccharides, oligosaccharides, and polysaccharides, covalently bonded to proteins and fats. Carbohydrates are integral to plant and arthropod…
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Zebrafish xenograft model: identification of novel mechanisms driving prostate cancer metastasis
Prostate cancer (PCa) is one of the most prevalent cancer in males.
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Molecular engineering of plant development using Agrobacterium-mediated protein translocation
Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa
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Subjects Barbarian, Monstrous, and Wild: Encounters in the Arts and Contemporary Politics
Subjects Barbarian, Monstrous, and Wild responds to a contemporary political climate in which historically invested figures of otherness—barbarians, savages, monsters—have become common discursive currency.
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Novel regulators of prostate cancer stem cells and tumor aggressiveness
Promotor: R.C.M. Pelger Co-Promotor: G. van der Pluijm
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World Archaeology
The department of World Archaeology combines research and education about regions all over the world, from Human Origins to the Middle Ages, and from Europe, to Asia, Africa and the America’s. That broad range in time and space makes the department a dynamic pluriform community with many different approaches,…
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Place: Towards a Geophilosophy of Photography
This month Ali Shobeiri's monograph, Place: Towards a Geophilosophy of Photography came out at Leiden University Press.
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On colonial grounds
A comparative study of colonialism and rural settlement in first millennium BC west central Sardinia
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PI3K signaling and adherens junctions in invasive lobular breast cancer
Invasive lobular carcinoma (ILC) is the second most common type of breast cancer.
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A pharmacognostic study of Vernonia guineensis Benth. (Asteraceae): bioactivity, safety, and phytochemical analysis
Promotor: Prof.dr. R. Verpoorte, , Co-Promotor: Young Hae Choi
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Microbial communities in Pampa soils; impact of land use changes, soil type and climatic conditions
Promotor: J.A. van Veen, Co-promotor: E.E. Kuramae
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Retrieving the Past Glory: Social Memory, Transnational Networks and Christianity in Contemporary China
Jifeng Liu defended his thesis on 2 February 2017
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Synthesis of chemical tools to study the immune system
This thesis describes the synthesis and biological evaluation of TLR2/6, TLR4, TLR7/8 and TLR9 ligands, of which the activity can be conditionally controlled.
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Conflict and Contest in Nietzsche's Philosophy
While Nietzsche's works and ideas are relevant across the many branches of philosophy, the themes of contest and conflict have been mostly overlooked. Conflict and Contest in Nietzsche's Philosophy redresses this situation, arguing for the importance of these issues throughout Nietzsche's work.
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Colonial and Global History
Colonial and Global History combines a deep curiosity of transcultural processes such as imperialism, (de)colonization, and globalization with critical historical research on regional societies in Africa, Asia, and the Americas.
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Superlattices in van der Waals materials: A Low-Energy Electron Microscopy study
n this PhD thesis, the recombination of different atomic lattices in stacked 2D materials such as twisted bilayer graphene is studied. Using the different possibilities of Low-Energy Electron Microscopy (LEEM), the domain forming between the two atomic layers with small differences is studied.
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Designing Ships using Constrained Multi-Objective Efficient Global Optimization
A modern ship design process is subject to a wide variety of constraints such as safety constraints, regulations, and physical constraints.
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Design and synthesis of metal-based chemotherapeutic agents for targeted DNA interactions or DNA repair pathway modulation
The research presented in this thesis explores the chemotherapeutic potential of metal-based compounds as chemotherapy agents, with an initial focus on the synthesis and DNA interaction studies of platinum and palladium compounds utilizing the [Pt(bapbpy)]2+ scaffold. The study identifies intercalation…
- Institute of Environmental Sciences
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Precarious Modernities
Assembling State, Space and Society on the Urban Margins in Morocco
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"Entrapment by Consent": the Co-ethnic Brokerage System among Ethnic Yi Labor Migrants in China
Xinrong Ma defended her thesis on 13 February 2018
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(Un)timely Crises: Chronotopes and Critique
Un)timely Crises explores how ‘crisis’—as a narrative, concept, grammar, and experience—structures time and space. This collectively written volume extends Bakhtin’s ‘chronotope’ to challenge mobilizations of crisis within neoliberal governmentality. The book explores how contemporary crises can trigger…
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Deciphering fermionic matter: from holography to field theory
Promotor: K.E. Schalm, Co-promotor: S.S. Lee
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Imaging complex model catalysts in action
From surface science towards industrial practice using high-pressure scanning tunneling microscopy.
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The Dutch and English East India Companies: Diplomacy, Trade and Violence in Early Modern Asia
The Dutch and English East India Companies were formidable organizations that were gifted with expansive powers that allowed them to conduct diplomacy, wage war and seize territorial possessions. But they did not move into an empty arena in which they were free to deploy these powers without resista…
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Development of kinase inhibitors and activity-based probes
Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt
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Leiden - Indonesia
Leiden University has a long tradition in the collaboration with Indonesia. For Leiden’s scholars in a wide range of disciplines, Indonesia’s biological, ecological, linguistic and religious diversity, its legal system, its emerging political role, its history and its people are an important object…
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Medical Biochemistry
Medical Biochemistry is a section of the Leiden Institute of Chemistry at Leiden University. The section is headed by Prof. Dr. Hans Aerts.
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Freedom in Captivity: Negotiations of Belonging along Kashmir's Frontier
How do borderland dwellers living along militarised frontiers negotiate regimes of state security and their geopolitical location in everyday life? What might 'freedom' mean to those who do not resist captivity engendered by borders? Focusing on the predicaments of a double-minority, Radhika Gupta examines…
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Negotiating Custom: A History of the Galle Landraad (1740-96)
Nadeera Seneviratne defended her thesis on 21 January 2016.
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Inducing spin triplet superconductivity in a ferromagnet
Promotor: J. Aarts
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In Perspective, quarterly publication
'In Perspective' is the quarterly publication of the Faculty of Humanities in which we bundle some of our most high-profile stories. In Perspective is printed in limited quantities (currently only available in Dutch), spread amongst relations and partners and offered on coffeetables within our buildings.…
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3 October parade
Leiden University will be taking part in the 3 October parade. Are you coming to watch?
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Antiviral Pharmacology
The focus of the Antiviral Pharmacology group led by Anne-Grete Märtson is optimizing antiviral therapy for different viral infections by conducting clinical trials and using innovative computational and dynamic laboratory methodologies.
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Confronting Colonial Objects: Histories, Legalities and Access to Culture
Carsten Stahn has just published Confronting Colonial Objects: Histories, Legalities and Access to Culture. The book is part of the OUP Cultural Heritage Law and Policy Series.
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Macromolecular Biochemistry
Macromolecular Biochemistry is a section of the Leiden Institute of Chemistry at Leiden University, comprising the PIs Marcellus Ubbink, Remus Dame, Aimee Boyle, Lars Jeuken and Anne Wentink.
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More JAZ in the orchestration of jasmonate-mediated plant defense
Promotor: Prof.dr. J. Memelink
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International Politics (MSc)
This master’s programme focuses on understanding the causes and consequences of armed conflict between states and within states. In addition, we explore whether and how local, national and international actors and institutions can forge cooperation, prevent political and armed conflict from emerging,…
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MicroSOS
The MicroSOS project is designed to bring together academic and industrial partners with different expertises to address challenges that agriculture is facing due to climate change and invests in the development of microbiome-based solutions towards more sustainable agricultural practices.
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Self Defense: Mimicking natural deterrent strategies in plants using adhesive spheres and volatiles
How can we make agricultural production systems more sustainable as the worldwide demand for healthy, safe food continues to grow? How can we develop healthy new food crops that have higher yields while requiring fewer harmful chemicals?
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Visible and Invisible: On Political Violence and Forms of Aesthetic Resistance to its Erasure and Distortion. One day symposium
Conference
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Expanding Social Sciences & Humanities in African Global Health Discourse
LUNHA strives to redefine global health by prioritizing justice, fairness, and inclusion in Africa. Through collaboration with diverse stakeholders, LUNHA aims to reshape global health research and foster a broader engagement with social sciences and humanities.
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Teaching
Research projects for students of the University of Leiden and other Dutch Universities are often available at the MacBio group. The research lines are also described in the Research section. For details of specific projects contact the supervisor (Ubbink, Dame, Boyle, Jeuken or Wentink).
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The battle against antimicrobial resistant bacterial infections - next stage development of antimicrobial peptides
PhD defence
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Activity-Based Proteasome Profiling
Promotor: H.S. Overkleeft, Co-promotor: B.I. Florea
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Inflammafish: Cross-talk between inflammation and autophagy in tuberculosis
Effective host defence against tuberculosis bacteria depends on a properly balanced level of inflammation. The Inflammafish project uses zebrafish larvae to study how autophagy controls this inflammation and vice versa.
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These Oppressions won't cease: An Anthology of the Political Thought of the Cape Khoesan, 1777–1879
The Khoesan were the first people in Africa to undergo the full rigours of European colonisation. By the early nineteenth century, they had largely been brought under colonial rule, dispossessed of their land and stock, and forced to work as labourers for farmers of European descent.
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Play and Media
Play and Media is one of the six research themes of the LUCAS Modern and Contemporary cluster.
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A Class of Their Own - Black Teachers in the Segregated South
In this book Adam Fairclough chronicles the odyssey of black teachers in the South from emancipation in 1865 to integration one hundred years later.
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Island Networks
The focus of this programme is the inter-community social relationships and transformations of island networks in the Lesser Antilles across the historical divide.