We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.

We carry a profound responsibility for our research animals and strive to provide them with the best possible quality of life. In our studies, we make every effort to avoid and minimise discomfort for the animals. Below, you can learn more about how this is put into practice.

We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.

Antwoord op veelgestelde vragen over onderzoek met proefdieren bij de Universiteit Leiden. FAQ

Animal experiments are not undertaken lightly; we are working with sentient beings. As scientists, we have great responsibility to handle laboratory animals with care. Read here how we consider and justify this.

Within Leiden University, we sometimes conduct research with laboratory animals. We only do this when when we cannot answer the research question in any other way.

We have facilities for various research animals, all of which naturally comply with legal requirements. We take great care of the animals, and our enclosures are designed to meet the specific needs of the different species.

At Leiden University, in both our biomedical and biological research, we use laboratory animals. Learn more about these specific areas of research and the goals we aim to achieve through these studies.

What does the interspecies interpretation of the equality principle mean for the liberal democracy, and is it possible to provide for an appropriate legal and political position for animals without defying the classic-liberal principles of the liberal democratic state?

In the research theme ‘Animal Sciences and Health’, we work with various animal species to gain insights into fundamental biological processes in both animals and humans.

The Animal Welfare Body Leiden (AWB) is an internal entity responsible for the well-being of all laboratory animals at Leiden University and the Leiden University Medical Center. It is actively involved in all aspects of research involving animals. The AWB has several legal responsibilities, including…

This part entails the analysis of an extensive sample of animal bone (c. 30,000 pieces) retrieved from well-defined archaeological contexts of the early period at Tell Sabi Abyad, c. 6800-6200 BC. It comprises aspects of taphonomy, ageing and osteometry, the reconstruction of the local spectrum of domestic…

Animal Sciences’ contributions to the Development & Disease research theme include the mechanisms and evolution of embryonic development, the development of cognitive mechanisms, and animal models for understanding mechanisms of human disease.

Animal Sciences’ contributions to the Biodiversity & Evolution research theme include evo-devo research, the evolution of cognitive and behavioural traits, and the evolutionary mechanisms of stress adaptation. This research involves both indoor and outdoor studies.

Keeping and breeding of test animals for the purpose of scientific research and education.

Main challenges in skin vaccination are overcoming the stratum corneum (SC) barrier and targeting the antigen presenting cells (APC) in the epidermis and the dermis.

Animal Sciences’ contribution to the Bioactive Molecules research theme includes research on molecules from natural sources, such as plants, insects, and snake venom, with the aim to identify novel anti-cancer, anti-inflammatory, anti-microbial, and anti-diabetic agents.

The eighth issue of the JLGC explores the diverse and interdisciplinary research on our multifaceted relationship with animals which is currently taking place, re-examining the relationship between humans and animals, and the definitions involved.

Our scientists working with laboratory animals undergo training on animal experiments. In this training, researchers learn how to handle laboratory animals responsibly. Read more about the requirements we set for researchers working with laboratory animals.

We use laboratory animals to address research questions, but only when there is no alternative and the question cannot be answered in any other way. Read here why we conduct animals experiments.

On 10 October 2019, Janneke Vink defended her thesis 'The Open Society and Its Animals'. The doctoral research was supervised by Prof. P.B. Cliteur.

Science begets technology but technology also begets science. Anne Urai from the Leiden Institute of Psychology is part of an international team team that rolls out a new, user-friendly, plug-and-play AI tool they hope will become an engine of discovery by quantifying the growing volume of recorded…

This thesis aims at thinking through the ethical position of animals in a way that differs radically from the manner in which this ethical position is thought within contemporary animal rights discourse.

Animal Sciences’ contributions to the Host-Microbe Interactions research theme focus on the interaction of animal hosts with pathogenic microbes but also the beneficial role of the gut microbiome.

Brendan Carroll promoted On Thursday October 30th Brendan Carroll successfully defended his PhD dissertation entitled:

Who is Economic Man? Every economic paradigm presupposes an anthropology, a theory of human nature. This project explores the anthropologies presupposed and produced by ancient Greek economic texts, and the specific knowledge forms that shape these anthropologies.

We aim to conduct as few animal experiments as possible. We are continually exploring methods to Replace, Reduce, and Refine animal experiments, commonly referred to as the three Rs. Additionally, we assess each study to ensure the implementation of the 3Rs has been maximised. The Animal Welfare Body…

Isotopic and zooarchaeological investigations in the Dominican Republic and Jamaica

In his dissertation Michiel Hooykaas outlines the results of six empirical research projects focused at biodiversity awareness in the Netherlands, specifically people’s knowledge about animals.

Mari Nakamura defended her thesis on 14 March 2017

My artistic practice deals with documents and, more specifically, with the use and the exploration of their narrative potential.

Apart from humans, animals play a pivotal role in travel literature.

Did early farmers deliberately use animal manure on their fields?

Leiden University investigates biodiversity not only in the Netherlands, but also abroad, with the goal of improving global nature conservation. We do so in collaboration with local universities. Education is also high on our agenda.

Appropriate animal models for intradermal vaccine delivery are scarce. Given the high similarity of their skin anatomy to that of humans, minipigs may be a suitable model for dermal vaccine delivery.

On 16 December 2019, Jan-Harm de Villiers defended his thesis 'The Anthropomorphic Hegemony of Subjectivity: Critical Reflections on Law and the Question of the Animal'. The doctoral research was supervised by Prof. P. Cliteur.

Anthropogenic noise has been shown to affect marine animals in various ways, this may have fitness consequences at individual and population level. This thesis aims to increase insight into the quantification of sound-induced behavioural responses that are relevant to fitness, and into factors that…

The Animated Image addresses the entire range of contexts in which images were described by Roman authors as being animated, as well as the accounts that Roman writers produced to explain the animation of inanimate matter.

How is inflammation in tuberculosis controlled by interplay between autophagy and inflammasome signalling?

Hekmat Dirbas defended his thesis on 14 February 2017

We should assume that animals can have feelings too. From an ethical point of view this should inform our dealings with animals, researchers from Leiden University and Utrecht University argue in an opinion article that was published in the scientific journal Affective Science on Thursday 10 March.

The quality of vaccines is still often tested by using laboratory animals. That has to change, according to researchers from Leiden University and the vaccinological institute Intravacc. Together they went searching for a test method that makes animal testing unnecessary. The first promising results…

Animal diet studies are critical for understanding ecological processes such as trophic interactions, energy flow, and nutrient cycling. By examining what animals consume, ecologists gain insights into species specialization, predator-prey relationships, and ecosystem management.

In the sixteenth and seventeenth centuries artists were fascinated by how the animal kingdom was classified. They were in some instances ahead of natural historians.

Testing chemical substances without using animals. It seems a utopia, but a European team is going to develop a way to make this a reality. The RISK-HUNT3R project, led by Leiden professor Bob van de Water, received 23 million euros from the European Commission for this purpose. The project was launched…

For the first time research has been done on species literacy in the Netherlands. Children in primary schools know about 1 in 3 native animal species. Publication in Biological Conservation.

There are miniaturisation beams, microrobots, and ice skaters who suddenly drop into a hole in the ice. Students of the local MBO Rijnland let their imagination run free while animating Leiden physics research. The result is eleven surprising and very diverse science animations.

Toxys, Leiden University and Leiden University Medical Center have agreed immediately to commercialise and also develop further the ToxProfiler technology invented at the two institutions. ToxProfiler allows for rapid toxicity hazard identification of novel and existing drugs, chemicals, and other substances.…