1,658 search results for “drug development” in the Public website
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Development of a academic monitoring system for students with learning problems in secondary school
Students with learning problems experience difficulties in reading, writing, and content-area learning into and throughout their secondary-school years
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Quantitative biology of polar auxin transport and plant development
The availability of complete plant genome sequences together with the ever increasing amount of data on the molecular, cellular and physiological mechanisms of plant development require mathematical and computational models to obtain a complete overview of and generate new insights into the quantitative…
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Pursuing new anti-cancer therapy as a team
Cancer is the leading cause of death in the Netherlands, and, with over 100 different types of cancer, it’s not a simple disease. Today, skin, breast, lung, prostate and colon cancer are the most diagnosed forms. Therefore, the discovery and development of new drugs has the ability to significantly…
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Cultural Anthropology and Development Sociology
Do you want to understand the complexities of today’s gender issues, social media use, food habits, social justice movements, labour relations or religious expressions? Join our international bachelor's programme in Cultural Anthropology and Development Sociology and get insight into people's social…
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Biotransformation of plant metabolites in microorganisms
- How to deconvolute metabolic mixture of precursors and products by biontransformation? - How to optimize the reaction conditions to produce bioactive compounds in biotransformation? - What is the effect of co-treating fungi or bacteria for biotransformations?
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The development of (beginning) teachers
How can teachers best learn from each other and develop? Jacobiene Meirink is conducting research on professional development for teachers in secondary education. She is particularly interested in how teachers collaborate on and learn from the development of teaching programmes. More insight into effective…
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Governance, entrepreneurship and inclusive development
Africa is rising and increasingly seen as a potential market by economic actors from Africa and the rest of the world. What is the interrelationship between governance, entrepreneurship and inclusive development?
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Development & Disease in Microbial Sciences
Microbial Sciences'contribution to the Development & Disease research theme is to perform world-class research to understand cellular morphogenesis, growth, development and virulence of microbes.
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Bio-Pharmaceutical Sciences (MSc)
The master’s programme of Bio-Pharmaceutical Sciences at Leiden University examines the research area of bio-pharmaceutical sciences and drug research. It offers seven specialisations ranging from BioTherapeutics to Industrial Pharmacy.
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Biophysical characterization of membrane protein-small molecule interactions
Promotor: M. Ubbink, Co-promotor: G. Siegal
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Why Leiden University?
The Leiden Institute of Chemistry (LIC) offers a unique tailor-made programme in Chemistry. You can customize the programme to your own interests and ambitions with the help of your own personal mentor. Your study will focus on either Chemical Biology or Energy & Sustainability. During the Master's…
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Animal sciences and health
In the research theme ‘Animal Sciences and Health’, we work with various animal species to gain insights into fundamental biological processes in both animals and humans.
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Novel chemical tools for target validation in neuroinflammation
In what way can new tools and techniques be used to develop drug candidates for the treatment of neurological disorders?
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Robert Rissmann appointed professor of Translational Dermatology at LACDR-CHDR
Pharmacist-clinical pharmacologist Robert Rissmann has been appointed Professor of Translational Dermatology. This extraordinary professorship has been created jointly by the Leiden Academic Centre for Drug Research (LACDR) and the Centre for Human Drug Research (CHDR) to strengthen their partnership…
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Rule of Law and Development
On 18 May 2011, Dr. Ben Knapen, Minister for European Affairs and International Cooperation, delivered the annual Van Vollenhoven Lecture on “Rule of Law and Development”.
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through Configurational and Mechanistic Lenses: Lessons for Concept Development
Valérie Pattyn, Assistant Professor at Leiden University, researched
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Inhibitor discovery of phospholipases and N-acyltransferases
In this thesis an activity-based probe was discovered that could visualize the activity of PLAATs. With an optimized gel-based ABPP assay in hand, screening of a compound library led to the discovery of alpha-ketoamides as a hit for PLAAT3.
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Working at the Faculty of Science
Working for a top faculty? Discover the vacancies at the Faculty of Science and apply immediately.
- Research Dossiers
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Cultural Anthropology and Development Sociology
We are very happy to welcome you to spend a semester or year studying with us at the Institute of Cultural Anthropology/Development Sociology (CA-DS). Here you will find practical information on studying CA-DS in Leiden as an exchange student.
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Cultural Anthropology and Development Sociology
Cultural Anthropology and Development Sociology is a social science. Anthropologists investigate the ways in which people give meaning to different aspects of their life and the way they interact with each other.
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Ovalbumin coated pH-sensitive microneedle arrays effectively induce ovalbumin-specific antibody and T-cell responses in mice
The aim of this work was to study the applicability of antigen-coated pH-sensitive microneedle arrays for effective vaccination strategies. Therefore, a model antigen (ovalbumin) was coated onto pH-sensitive (pyridine-modified) microneedle arrays to test pH-triggered antigen release by applying the…
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Sex effects on development of brain structure and executive functions: Greater variance than mean effects
This study is the first to directly relate brain development to sex differences and school performance. The results debunk the myth that brain development is slower in boys.
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Research
The current projects of the Molecular Physiology group focus on proteins of the endocannabinoid system, kinases and antibacterial targets. MSc- and BSc-students can contact Jessica van Krimpen-Kraaijenoord to apply for research internships.
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Design and application of dextran based cross-linked networks
This thesis describes the design, characterization and application of dextran based crosslinked network.
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Streptomyces as cell factories
We aim to engineer streptomycetes to fully exploit their potential for natural product productions, by a rational design and evolution approach.
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Executive deficits, behavioural problems and early reading development
This study tests whether behavioural problems at a young age are related to early reading and mathematics development.
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European Lead Factory
The European Lead Factory has been created with the ultimate goal to develop lead drug candidates to address neglected diseases including bacterial infections, psychiatric disorders and oncology.
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Cultural Anthropology and Development Sociology
Vulnerability and the associated levels of social resilience is what fascinates the researchers at the Institute of Cultural Anthropology and Development Sociology. What links a Japanese fisherman after the tsunami at Fukushima with a Ghanaian goldminer in an increasingly industrialised work environment?…
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Ruthenium-peptide conjugates for targeted phototherapy
As leading cause of death worldwide, cancer is responsible for nearly 10 million deaths in 2020 according to World Health Organization (WHO). Cisplatin and its derivatives are commonly used chemotherapy agents for current cancer treatment in the clinics.
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Strategy
The division of BioTherapeutics consists of the former divisions Biopharmaceutics and Drug Delivery Technology.
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Mood variability during adolescent development and its relation to sleep and brain development
During adolescence, mood disorder onset peaks. Mood variability is associated with negative mental health outcomes, so understanding biological factors that might be associated with mood variability, such as sleep and structural brain development, could elucidate the mechanisms underlying mood and anxiety…
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Systems pharmacology of the endocannabinoid system
In this thesis, a system pharmacology approach, integrating metabolomics, pharmacology and chemical biology, was applied to understand and modulate the endocannabinoid system across different model systems (cells, zebrafish, mice and humans).
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Prediction of brain target site concentrations on the basis of CSF PK: impact of mechanisms of blood-to-brain transport and within brain distribution
Promotor: Prof.dr. M. Danhof, Co-promotor: E.C.M. de Lange
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Vascular and Regenerative Medicine
Methods of treatment for chronic illnesses are limited. Doctors and researchers at Leiden University Medical Center (LUMC) and Leiden University are working on new therapies as an alternative for organ transplants. The goal is to cure the illnesses by restoring organs to their original function. Stem…
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Research
Central elements in the research activities of all programme group members are: attachment, sensitive caregiving, and prevention and intervention.
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Strategy
The research area of this division is focused on the development of novel therapeutic modalities and novel concepts in early drug discovery, in order to better predict ligand-target interactions.
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COVID-19 Research and Education at Leiden Academic Centre for Drug Research
Since the start of the Corona crisis, several COVID-19 related research and teaching projects were started at LACDR. The computational and teaching activities started right away, as well as a large-scale metabolomics screening program by Thomas Hankemeier’s group. Other experimental activities are still…
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Peace, Justice and Development (Advanced LL.M.)
The specialization Peace, Justice and Development at Leiden University examines the legislation that governs international relations in a global society.
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Determining the kinetic profile of ENT1 inhibitors
Supervisor: Anna Vlachodimou
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Endocannabinoids in health and stress
How does the endocannabinoid system in the zebrafish function at the molecular and phenotypic levels and how is it linked to the stress axis?
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Cancer pathogenesis and therapy
With cancer, a person’s body cells grow uncontrollably. Putting together a detailed picture of how this comes about makes it possible to develop efficient therapies. Researchers at the Leiden University Medical Centre (LUMC) and Leiden University are working together to gain a better understanding…
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cross-contextual media landscape: Children’s digital media use and their social development
For this project we delve into children's digital media use during the transition from kindergarten to group 3 and investigate its impact on their social development.
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redesigning a program using characteristics of effective instructional development
In this research project characteristics of effective instructional development were identified that are appealing to medical teachers and relevant for medical education.
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Conquering the fortress: New strategies for the treatment of tuberculosis
Can we exploit the cell death machinery of the host to develop new host-directed anti-TB treatments?
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Evolution and development of bitterling fish
How has early development in R. ocellatus been modified as a result of its parasitic embryonic lifestyle?
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Applied Neuroscience in Human Development (MSc)
Are you interested in the neurocognitive and biological roots of learning, behaviour and emotions in children? If so, the programme in Applied Neuroscience in Human Development might be the specialisation you are looking for.
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The development of children in foster care
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BioTherapeutics (MSc)
The master’s specialisation BioTherapeutics at Leiden University is a two-year programme which trains students in research in specific drug delivery techniques. The programme also examines the development of new therapeutic approaches to treat immune-based disorders, such as atherosclerosis, metabolic…
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Career and development - Working at Leiden University
If you have the ambition to continuously develop and grow in your work, then Leiden University is an attractive employer for you.