The Effects of the 1881 Liquor Act on the Leiden Alcohol Trade

Self-censorship violates principles of a free society but few people want to take the role of the martyr.

Agriculture is among the most vulnerable sectors to climate change and poorer countries face the most severe difficulties. Coffee farmers in Central America, for instance, are facing multiple and mutually reinforcing crises, including price shocks, outbreaks of pests and diseases, migration, and farm…

This thesis describes how different colours of light affect various aspects of the growth and development of Arabidopsis and tomato plants⁠.

This thesis investigates a pharmacological challenge model induced by Toll-like receptor 7 (TLR7) activation, focusing on skin inflammation and its implications for early drug development.

This thesis describes the design, synthesis, and immunological evaluation of varying (neo)antigenic peptide conjugates containing either a TLR2 or a TLR7 agonist.

The objective of this study was to investigate the expression and function of GRHL2 in different breast cancer subtypes.

Brexit has been a kind of shock therapy for the EU and has eventually led to more appreciation for European cooperation. That is what Professor Luuk van Middelaar claimed on 30 November at the conference ‘Brexit and the future of the European Union’ which marked the 60th anniversary of the Europa Institute…

Nature, nurture and neural mechanisms of social emotion regulation in childhood

Toll-like receptors (TLRs) are central components of the innate immune system, functioning as pattern recognition receptors that detect microbial- and damage-associated molecular patterns and initiate antimicrobial and inflammatory responses.

Many members of the Dutch Royal Family have studied at Leiden University and several have been awarded an honorary doctorate. In 1987, current King Willem-Alexander followed in the academic footsteps of his mother Beatrix, his aunt Margriet and his grandmother Juliana, and started his History studies…

Advanced UHF MRI techniques provide powerful tools for studying the zebrafish brain, an emerging model in neurological research. In this work, various MRI and localized MRS methods are optimized and employed for UHF strength for studying the zebrafish brain.

The main aim of my Ph.D. thesis is to further explore the value of using early developing zebrafish larvae (up to 5 dpf) as a model to study anxiety-like behaviour and their pharmacological modulation with drugs.

This September, Adina Akbik received the Political Science Teaching Award at Leiden University. Created by student members of the Bachelor's and Master's Programme Committees (OLC), the award recognises remarkable teaching at the Institute. Akbik was chosen from five finalists after receiving several…

Breast cancer is the most common cancer in women worldwide. Metastasis, the process by which cancer cells spread to other parts of the body, makes treatments less effective. It is important to unravel the mechanism of metastasis.

From memorials to the armed forces to memory stones for individual victims. It was only later that the Holocaust took a central role in Western remembrance culture, Cleveringa Professor Frank van Vree notes. ‘Nationalists and human rights activists both invoke the experience of the Holocaust.’

This article provides a comprehensive analysis of the Islamic State's use of images taken by drones, drawing on a dataset of ISIS propaganda images from October 2016 to December 2018.

Young babies laugh like adult apes do: producing sounds while inhaling and exhaling. Adult humans produce sounds on the exhale only. Cognitive psychologist Mariska Kret and colleagues have published an article about the development of human laughter in the journal Biology Letters.

Can we study what makes us human through the eyes of a robot? Peter van der Putten and Maarten Lamers at the Leiden Institute of Advanced Computer Science are collecting examples of robots with humanlike qualities: emotional, creative, curious, helpless and even religious robots.

Wouter Moerland is on a two-year secondment as ecology adviser at the Municipality of Leiden. This biology alumnus talks animatedly about his work. ‘We’re working hard to increase nature’s chances in town.’

Contraband and forced recruitment: How rebels' exploitation of natural resources can increase their willingness to forcibly recruit children.

Relevant safety issues are associated with hazardous materials transportation, especially when transport routes cross populated areas. This article for the Journal of Loss Prevention in the Process of Industries analyses a 2015 accident with a freight train in Tilburg, comparing it to the Viareggio…

The function of TLRs in innate immunity has aroused worldwide attention soon after its discovery. Because of the broad functions of TLR2 in innate immunity, the drive for the development of TLR2-targeted vaccines or therapeutic treatments has accelerated in the last decades.

Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez

Does student and teacher gender affect students’ performance and what is the role of gender stereotypes in this relation?

This project is funded by the Dutch Cancer Society. The project will be part of an ongoing research line aimed at identifying mechanisms of cancer therapy resistance and metastasis. In this project, it will be investigated how the Grainyhead family of transcription factors controls therapy response…

During an inspiring meeting at the Health Campus The Hague on 2 April, Jan Anthonie Bruijn and Jet Bussemaker reflected on their experiences in politics and looked ahead to the future of Dutch healthcare.

Science Magazine has published three back-to-back papers on an important discovery in solid state physics. Leiden physicist Jan Zaanen wrote a Perspective article on the subject in the same issue of 4 March.

What's it like studying abroad? Noor Ismail and Charlot Oltmans share their experiences in videos made in Hhangzhou and Oslo.

Arteriosclerosis bears great similarities to autoimmune diseases. Researchers from Leiden University show this in a new study they published in the renowned scientific journal Nature Cardiovascular Research. 'This discovery suggests that treatment methods for autoimmune diseases might also be effective…

Hardly anyone in the Netherlands ever watches skeleton racing. But we’ll soon be glued to our TV sets when ‘our’ Kimberley Bos slides down the track at the Olympic Games. All because she stands a good chance of winning a medal. Why do we like winners so much?

The people who lived in Saqqara, City of the Dead in Egypt, died thousands of years ago, but they are not all that different from us. This is what a study by the National Museum of Antiquities in Leiden, The Netherlands concludes. If you wanted to prove that you had good taste in ancient Egypt then…

Microscopic swimmers such as bacteria do not always swim alone. There are advantages to exchanging information and cooperating. Stefania Ketzetzi and colleagues now show in Nature Communications that human-made microswimmers, too, can cooperate.

Wija Wijayanto and Arum Perwitasari both were Indonesian PhD students at Leiden University, funded by the Leiden-DIKTI Graduate Scholarship Programme. With the help of this scholarship, literally thousands of students travel abroad to write their dissertations. During their research period, Arum and…

Chapter 2 describes a post-synthetic methodology to introduce a fluorescent label in highly lipophilic, Pam3Cys based conjugates.

Wija Wijayanto and Arum Perwitasari both were Indonesian PhD students at Leiden University, funded by the Leiden-DIKTI Graduate Scholarship Programme. With the help of this scholarship, literally thousands of students travel abroad to write their dissertations. During their research period, Arum and…

On the 20th of April, Chams Benoît Bernard successfully defended a doctoral thesis. The Leiden University Centre for Linguistics congratulates Chams on this achievement!

On Saturday 13 October the historical city Leiden was crowded with prospective students visiting the Open Day. They all came to Leiden to orientate themselves towards studying at Leiden University or to ask questions about the content of the bachelor’s programmes. Among them were a lot of international…

What is it like to be old? Many young people cannot really imagine what it is like. For a group of Honours students, however, this question has been answered. They had the chance to wear an age simulation suit during the Bachelor Honours Class ‘Vitality and Ageing’.

What is it like to be a Leiden University student at Campus The Hague? These prospective students found out on the Experience Day of 30 March.

Guiding high school students as a mentor at Pre-University College: what is that like? And what does it all entail? As part of the 20th anniversary of PRE-College Leiden, we asked two experienced PRE-mentors about their job - and what makes their work so meaningful. ‘You really see them grow.’

Professor of Higher Education Estela Mara Bensimon approaches diversity from a specific viewpoint. Examine and reflect on your own motives, is her advice to lecturers. Do you know for sure that you don't treat students from minority groups differently?

Women’s football is steadily gaining attention. It’s as though the sport is becoming emancipated. And yet in conversations with professional female footballers philosopher Nathanja van den Heuvel discovered that a male culture still prevails. Female footballers often feel like second-class athletes,…

Junk news sites with unknown names such as Trendnieuws and Viraal Vandaag reach millions of Dutch people thanks to their Facebook pages. Messages from those pages are much more often shared and liked than messages from pages from well-known news media such as De Telegraaf, NOS and NU.nl. This is shown…

Europe’s security suddenly looks uncertain now President Trump has started negotiations with Putin. What does this mean for the Netherlands? What do we need to do?

Film screening & panel discussion