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701 search results for “smit barrier re-pair” in the Public website

• Lipids as therapeutic targets for barrier repair in skin diseases Research output

  The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.

• A novel formulation for skin barrier repair : from ex vivo assessment towards clinical studies Research output

  The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.

• An ex vivo human skin model for studying skin barrier repair Research output

  In the studies described in this study, we introduce a novel ex vivo human skin barrier repair model. To develop this, we removed the upper layer of the skin, the stratum corneum (SC) by a reproducible cyanoacrylate stripping technique.

• A novel biofilm for skin barrier repair of patients with atopic eczema Research project

  Atopic eczema is a skin disease with increasing incidence currently affecting 25% of the paediatric population. In atopic eczema the skin barrier function is reduced. This barrier is formed by the outermost layer of the skin called the stratum corneum (SC). The SC consists of terminally differentiated…

• Skin Barrier and Vaccination

  The Skin Barrier and Vaccination group is led by Prof. Joke Bouwstra. One of the key functions of the skin is its barrier function, which is located in the uppermost layer of the skin, the stratum corneum. The stratum corneum consists of enucleated dead cells (corneocytes) embedded in a lipid matrix.…

• Green Bikes & Repair Points Leiden University Green Office

  Bikes are one of the most sustainable ways of travel which use should be promoted by the University.

• How protein modifications cooperate to repair DNA Research project

  How do protein modifications work together to repair DNA, and what can we learn about these interactions to better understand disease?

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  Emile Smits Teacher

  Faculty of Humanities

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  Ashley Smit Guest employee

  Faculty of Social and Behavioural Sciences

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  Egbert Smit Professor

  Faculty of Medicine

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  Maartje Smit Skills Lecturer

  Faculty of Social and Behavioural Sciences

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  Benthe Smit PhD candidate

  Faculty of Science

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  Johannes Smit Professor

  Faculty of Medicine

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  Elisa Smit Communications Officer

  Student and Educational Support

• Impaired barrier of inflammatory skin diseases Research project

  Focus in skin research

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  Johan Smit Operational technician

  University Facility Services

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  Wanda Smit Management assistant

  Administration and Central Services

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  Dana Smit Lecturer

  Faculty of Social and Behavioural Sciences

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  Hemmo Smit Lecturer

  Faculty of Social and Behavioural Sciences

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  Flora Smit PhD candidate

  Faculty of Humanities

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  Vincent Smit Professor

  Faculty of Medicine

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  Jorrit Smit Visiting researcher

  Faculty of Social and Behavioural Sciences

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  Corné Smit Guest lecturer

  Faculteit der Rechtsgeleerdheid

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  Ben Smit Researcher

  ICLON

• 
  Michiel Smit PhD candidate

  Faculteit der Rechtsgeleerdheid

• Development of human skin equivalents to unravel the impaired skin barrier in atopic dermatitis skin Research output

  Promotor: J.A. Bouwstra Co-promotor: A. El Ghalbzouri

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  Diederik Smit Assistant professor

  Faculty of Humanities

• 
  Sander van der Smit Privacy Officer

  Administration and Central Services

• Knowledge of DNA repair in the fight against tumour cells Research Dossier: Collaborative and effective drug development

  What is the most effective way to eliminate tumour cells? The DNA repair mechanism could play an important role in increasing the effectiveness of chemotherapy in the fight against cancerous cells. If we are to influence this mechanism, we need fundamental knowledge about how the mechanism works.

• Human skin equivalent barrier optimization Research project

  The currently available in vitro generated human skin equivalents resemble the human skin in many aspects. However, some essential barrier characteristics do not fully mimic the native barrier. Consequently, the human skin equivalents cannot be used for screening of drugs for skin penetration.

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  Monique Smits Library staff member

  Leiden University Libraries

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  Lola Smits Trainee

  Faculty of Science

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  Ileen Smits Project manager

  Administration and Central Services

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  Hermelijn Smits Professor

  Faculty of Medicine

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  Sharon Smits Student counsellor

  Student and Educational Support

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  David Lifshitz Smit

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  Robert Smits Staff Member Reception

  University Facility Services

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  Bart de Smit Vice Dean / professor

  Faculty of Science

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  Heleen Smits Scientific Information Specialist

  Afrika-Studiecentrum

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  Tirza Smits Blended Learning officer

  Faculty of Social and Behavioural Sciences

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  Rinske Smits Study adviser

  Faculty of Humanities

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  Maaike Smit-Maaroufi Admissions Officer

  Student and Educational Support

• atopic dermatitis: investigating the role of filaggrin in the skin barrier Research output

  Promotor: Prof.dr. J.A. Bouwstra, Co-promotor: Dr. A. El Ghalbzouri

• 
  Lieke Smits Postdoc

  Faculty of Humanities

• Barrier properties of an N/TERT based human skin equivalent Research output

  Human skin equivalents (HSEs) can be a valuable tool to study aspects of human skin, including the skin barrier, or to perform chemical or toxicological screenings.

• The importance of free fatty acid chain length for the skin barrier function in atopic eczema patients Research output

  An important feature of atopic eczema (AE) is a decreased skin barrier function. The stratum corneum (SC) lipids - comprised of ceramides (CERs), free fatty acids (FFAs) and cholesterol - fulfill a predominant role in the skin barrier function.

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  Ivo Smits Professor

  Faculty of Humanities

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  Felix Smits Researcher

  Faculty of Science

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  Imme imme Smits guest

  Faculty of Humanities

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  Maaike Smit-Beemsterboer Study adviser

  Faculty of Governance and Global Affairs