Synthetic cells, also known as artificial cells or protocells, have wide ranging applications from drug delivery vectors to cell models. In biotechnology they can function as micro- or nanoreactors with possible applications in biocatalysis and photocatalysis. Phospholipids are by far the most commonly…

Does a moving hybrid zone leave a genomic footprint?

Hybrid Intelligence (HI) is the combination of human and machine intelligence, expanding human intellect instead of replacing it. HI takes human expertise and intentionality into account when making meaningful decisions and perform appropriate actions, together with ethical, legal and societal values.…

Hybrid zones occur where two species meet and produce offspring (hybrids). Typically, hybrids show a considerable reduction in fitness. In this thesis two hybrid zones are treated.

This dissertation explores how Large Language Models (LLMs) can effectively and responsibly contribute to complex decision-making processes. By combining AI and human intelligence, Hybrid Intelligence (HI) emerges, allowing the strengths of both humans and machines to be utilized.

A comparative analysis of legitimation strategies in tree hybrid regimes: Russia, Venezuela, and Seychelles.

There are about 35,000 students with chronic illnesses in the Netherlands. If they cannot receive education in the classroom, they may be able to do so from home or a hospital with hybrid education. The question in this study is: how can interaction with the teacher and fellow students be promoted?

A Josephson junction is a device where a thin insulating barrier or a nanostructure is placed between two superconducting leads. Such a junction is essential to superconducting qubits that store quantum information due to its anharmonic spectrum.

This project involves research into the oeuvre of the Sundanese sculptor Iko, who has worked for the Catholic mission in Java and has carved sculptures for a chapel and church in Ganjuran. The images were designed by the Catholic layman Jos Schmutzer and are characterized by a fusion in style and symbolism…

Metal complexes and 2D materials like graphene were combined to produce structures that can function as sensors.

PhD defence

On 2 April 2025, Anna Marhold, a member of the Peace and Security Committee of the AIV and Assistant Professor at the Grotius Centre for International Legal Studies, joined a technical briefing to parliament providing advice on hybrid threats and societal resilience.

Bart Schuurman sheds light on the alarming trend in both the frequence and geographical spread of these incidents with The Parliament Magazine.

Our annual "Science to Experience" exhibition of student works is hosted by the V2_ Lab for the Unstable Media. This year's theme is "HYBRID".

From 11-13 April 2019, a group of 11 students from LUC and the Advanced MSc. programme in International Relations and Diplomacy attended the event NATO@70 in Portugal – Countering hybrid threats with hybrid containment: NATO’s mission for the 21st century. Leiden University’s participation in the event…

Since September, a large part of education is 'hybrid': students can attend courses both at home (online) and in person in lecture halls. How do students themselves feel about this? We asked Emma and Cornelia of the Research Master Classics and Ancient Civilizations.

Promotor: H.J.M. de Groot

‘It is OK for employees to work flexibly, as long as they spend 40 hours in the office’, said Elon Musk in June 2022. Are we back where we started now that the pandemic is over? What is needed to make flexibility prosper? Helen Pluut is researcher in Organizational Behaviour at Leiden University and…

Ben Wielstra studies hybrid zones, regions in which distinct populations of organisms meet, mate and produce genetically admixed offspring. In the journal Current Biology, he introduces hybrid zones in an accessible way.

Raffaele Marchetti (2021). Hybrid Diplomacy with NGOs: The Italian Formula. Cham: Palgrave Macmillan. ISBN 978-3-030-86869-7, 135 pp., €46.00 (eBook).

From 16 to 19 September 2021 a hybrid conference will take place on animation in the Middle Ages. This conference is a cooperation between the University of Bergen (Norway) and the A. Zelwerowicz National Academy of Dramatic Art in Warsaw, Branch Campus in Bialystok (Poland).

Drugs-related violence in Mexico is similar in terms of dynamics and strategy to the IS hybrid war in the West. This is the claim made by Teun Voeten. PhD defence 20 September.

A consortium made up of Leiden University (Institute of Public Administration/Digitalisation & Public Policy, Bram Klievink, Sarah Giest, Bart Schermer), VU (Professor Fabio Massacci), TU Delft, TNO, and Thales has been awarded a NWO grant of 1.5 million euros. This research project looks into the ‘metadata…

You have prepared a research project, put together a plan, and you are ready to travel to the country where you will be conducting your fieldwork. What do you do when Covid suddenly makes that impossible? Nadia Sonneveld was forced to relocate her project Living on the Other Side to a hybrid form: ‘It…

This thesis pioneers diatom molecular identification and quantification through genome-scale methods, with four key aims: (i) reviewing DNA/RNA sequencing methods in aquatic biomonitoring to highlight their strengths and limitations;

University lecturer Steven Lauritano has been awarded a Comenius Teaching Fellow grant. Lauritano will use the grant of 50,000 euros to improve hybrid education in classes featuring particular objects.

De menselijke geschiedenis strekt zich ver uit vóór de tijd waarin de mensen opschreven wat er zoal gebeurde.

Triplet superconductivity refers to a condensate of equal-spin Cooper pairs (pairs of electrons with equal spin).

Tuberculosis is a major global health problem caused by the Mycobacterium tuberculosis complex, claiming more than a million lives annually.

On the 3rd of April, Sebastiaan van der Lubben successfully defended a doctoral thesis. The Leiden University Centre for Linguistics congratulates Sebastiaan on this achievement!

Kralen spreken tot de verbeelding. Ze zijn aantrekkelijk en persoonlijk vanwege hun kleuren, materialen, patronen en associaties. Je draagt ze op je lichaam, waar je ze voelt en anderen ze zien. Kralen zijn waardevol en verplaatsbaar, tegelijkertijd reizigers en souvenirs.

Promotor: Prof.dr. J. Memelink

Een scheepswrak, zijn bemanning en het leven in de 18de eeuw

Since the invasion of Ukraine in 2022, Russia has been conducting a covert sabotage campaign against Europe. The ‘Bewaken en Beveiligen’ (Surveillance and Security) project team at Leiden University has investigated the scale of these operations and compiled its findings in the report Russian Operations…

Synthetic or artificial cells are vesicles, often lipid vesicles, with wide ranging applications from drug delivery to nanoreactors in biocatalysis. We are developing polymer-lipid hybrid vesicles for applications in compartmentalised biocatalysis, in which the polymer has been shown to greatly enhance…

How does invasive hybridization affect threatened native species?

Overlevingsanalyse is een onderzoeksgebied dat zich richt op het bestuderen van de tijd tot het optreden van een specifieke uitkomst.

Training and Exercising in Crisis management and Emergency Control

Polymyxins are clinically used antibiotics, discovered in mid-20th century. Once abandoned due to excessive nephrotoxicity, they are now used increasingly to address infections caused by multi-drug resistant Gram-negative bacteria.In this thesis, we describe the development and synthesis of analogues…

Research in the Lars Jeuken group focusses on redox-active proteins and membranes enzymes, aiming to understand bacterial respiration at the molecular level for the development of antimicrobials and semi-artificial photo-synthetic cells.

A sustainable resource management is an essential aspect to satisfy the current human needs without compromising the needs of future generations.

Leiden has much to celebrate: first, 450 years of the Relief of Leiden and then 450 years of Leiden University. And that is no coincidence.

We use DNA strands to stabilize few-atom silver clusters, which show unique optical and chemical properties. This thesis involves the study of these constructs for various applications.