Synthetic cells, also known as artificial cells or protocells, have wide ranging applications from drug delivery vectors to cell models. In biotechnology they can function as micro- or nanoreactors with possible applications in biocatalysis and photocatalysis. Phospholipids are by far the most commonly…

Does a moving hybrid zone leave a genomic footprint?

Hybrid Intelligence (HI) is the combination of human and machine intelligence, expanding human intellect instead of replacing it. HI takes human expertise and intentionality into account when making meaningful decisions and perform appropriate actions, together with ethical, legal and societal values.…

Hybrid zones occur where two species meet and produce offspring (hybrids). Typically, hybrids show a considerable reduction in fitness. In this thesis two hybrid zones are treated.

This dissertation explores how Large Language Models (LLMs) can effectively and responsibly contribute to complex decision-making processes. By combining AI and human intelligence, Hybrid Intelligence (HI) emerges, allowing the strengths of both humans and machines to be utilized.

This thesis investigates how quantum, quantum-inspired, and hybrid quantum-classical computation can enhance key points of the automated machine learning (AutoML) pipeline under the constraints of noisy intermediate-scale quantum (NISQ) devices.

A comparative analysis of legitimation strategies in tree hybrid regimes: Russia, Venezuela, and Seychelles.

There are about 35,000 students with chronic illnesses in the Netherlands. If they cannot receive education in the classroom, they may be able to do so from home or a hospital with hybrid education. The question in this study is: how can interaction with the teacher and fellow students be promoted?

A Josephson junction is a device where a thin insulating barrier or a nanostructure is placed between two superconducting leads. Such a junction is essential to superconducting qubits that store quantum information due to its anharmonic spectrum.

This project involves research into the oeuvre of the Sundanese sculptor Iko, who has worked for the Catholic mission in Java and has carved sculptures for a chapel and church in Ganjuran. The images were designed by the Catholic layman Jos Schmutzer and are characterized by a fusion in style and symbolism…

Metal complexes and 2D materials like graphene were combined to produce structures that can function as sensors.

On 2 April 2025, Anna Marhold, a member of the Peace and Security Committee of the AIV and Assistant Professor at the Grotius Centre for International Legal Studies, joined a technical briefing to parliament providing advice on hybrid threats and societal resilience.

Our annual "Science to Experience" exhibition of student works is hosted by the V2_ Lab for the Unstable Media. This year's theme is "HYBRID".

Promotor: H.J.M. de Groot

Ben Wielstra studies hybrid zones, regions in which distinct populations of organisms meet, mate and produce genetically admixed offspring. In the journal Current Biology, he introduces hybrid zones in an accessible way.

Raffaele Marchetti (2021). Hybrid Diplomacy with NGOs: The Italian Formula. Cham: Palgrave Macmillan. ISBN 978-3-030-86869-7, 135 pp., €46.00 (eBook).

From 16 to 19 September 2021 a hybrid conference will take place on animation in the Middle Ages. This conference is a cooperation between the University of Bergen (Norway) and the A. Zelwerowicz National Academy of Dramatic Art in Warsaw, Branch Campus in Bialystok (Poland).

This article examines Russia’s use of low-level agents in covert operations across Europe since 2022, analysing a dataset of 145 cases to identify patterns in recruitment, demographics and network structure using social network analysis.

This thesis pioneers diatom molecular identification and quantification through genome-scale methods, with four key aims: (i) reviewing DNA/RNA sequencing methods in aquatic biomonitoring to highlight their strengths and limitations;

De menselijke geschiedenis strekt zich ver uit vóór de tijd waarin de mensen opschreven wat er zoal gebeurde.

Tuberculosis is a major global health problem caused by the Mycobacterium tuberculosis complex, claiming more than a million lives annually.

Triplet superconductivity refers to a condensate of equal-spin Cooper pairs (pairs of electrons with equal spin).

On the 3rd of April, Sebastiaan van der Lubben successfully defended a doctoral thesis. The Leiden University Centre for Linguistics congratulates Sebastiaan on this achievement!

In this project, researchers from computer science, law, psychology, and public administration research in practice how artificial intelligence (AI) can be leveraged to make decision-making in the security domain more effective, while also keeping it safe and accountable.

Effective policy-making requires understanding what truly causes a problem. Only then can policymakers develop targeted interventions that achieve desired outcomes.

Kralen spreken tot de verbeelding. Ze zijn aantrekkelijk en persoonlijk vanwege hun kleuren, materialen, patronen en associaties. Je draagt ze op je lichaam, waar je ze voelt en anderen ze zien. Kralen zijn waardevol en verplaatsbaar, tegelijkertijd reizigers en souvenirs.

Promotor: Prof.dr. J. Memelink

Een scheepswrak, zijn bemanning en het leven in de 18de eeuw

Synthetic or artificial cells are vesicles, often lipid vesicles, with wide ranging applications from drug delivery to nanoreactors in biocatalysis. We are developing polymer-lipid hybrid vesicles for applications in compartmentalised biocatalysis, in which the polymer has been shown to greatly enhance…

Overlevingsanalyse is een onderzoeksgebied dat zich richt op het bestuderen van de tijd tot het optreden van een specifieke uitkomst.

How does invasive hybridization affect threatened native species?

Polymyxins are clinically used antibiotics, discovered in mid-20th century. Once abandoned due to excessive nephrotoxicity, they are now used increasingly to address infections caused by multi-drug resistant Gram-negative bacteria.In this thesis, we describe the development and synthesis of analogues…

Research in the Lars Jeuken group focusses on redox-active proteins and membranes enzymes, aiming to understand bacterial respiration at the molecular level for the development of antimicrobials and semi-artificial photo-synthetic cells.

Leiden has much to celebrate: first, 450 years of the Relief of Leiden and then 450 years of Leiden University. And that is no coincidence.

A sustainable resource management is an essential aspect to satisfy the current human needs without compromising the needs of future generations.

Blended and hybrid teaching are presented as crucial in promoting teaching innovation, as well as more flexible study approaches allowing students to develop their own tailor-made study programmes. While the strategy document focuses on the positive aspects of digital teaching tools, no systematic study…

We use DNA strands to stabilize few-atom silver clusters, which show unique optical and chemical properties. This thesis involves the study of these constructs for various applications.

Wordt het nog wat met de Arabische lente?

Voor zowel archeologen, paleontologen en geologen als vrijwilligers in de archeologie en paleontologie is het geen verrassing meer dat op de stranden van de Nederlandse kust fraaie vondsten gedaan kunnen worden. Vele artikelen, boeken, tentoonstellingen, congressen, lezingen, ‘zoekdagen’, krantenberichten,…

Book Presentation | Studium Generale Lecture