622 search results for “3d modelling” in the Public website
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Guiding evolutionary search towards innovative solutions
Promotors: Prof.dr. T.H.W. Bäck, Prof.dr. B. Sendhoff (Technische Universität Darmstadt)
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PI3K signaling and adherens junctions in invasive lobular breast cancer
Invasive lobular carcinoma (ILC) is the second most common type of breast cancer.
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Quantifying the toxicity of mixtures of metals and metal-based nanoparticles to higher plants
Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver
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Liselore Tissen
Faculty of Humanities
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dr. ir. Hai-Xiang Lin working on Data Analytics for Environmental Modelling joins CML
Prof.dr.ir. Hai-Xiang Lin is appointed on 1 March 2015 as part-time professor on Data Analytics for Environmental Modelling at CML on behalf of the R. Timman foundation. He will join the CML-department of Industrial Ecology. He has a position at the Department of Applied Mathematics at the Faculty…
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Advances in Survival Analysis and Optimal Scaling Methods
This thesis is based on five papers on several topics.
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Leiden Academic Centre for Drug Research
Drug development is a complex process in which many parties work together. Every day, the researchers at LACDR devote their energies to developing drugs that are new, better, more efficient and easier to produce. And thus to the millions of patients who know all too well why this research in Leiden…
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Joost Beltman
Science
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MULTIPLY - MULTIscale SENTINEL land surface information retrieval Platform
Aim: To develop and enable application of a practical, flexible, user-friendly platform to provide the scientific community with a tool to generate land surface products and its associated uncertainties and exploit these for data-intensive science.
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Software development by abstract behavioural specification
The development process of any software has become extremely important not just in the IT industry, but in almost every business or domain of research.
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Mathematical model helps to explain the formation of spine and ribs
Mathematical biologists from Leiden have developed a model that helps to explain how the spine and vertebrae, among other things, form during embryonic development. The same process, the other way around, plays a key role in cancer metastasis. Publication in iScience.
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Infrastructure
An overview of our infrastructure at the SPP division:
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Determining the structure of a chemotaxis kinase complex with receptor mimetics and cryo-EM
Can we determine the 3D structure of a chemotaxis core complex using single-particle reconstructions via cryo-EM?
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NMR structural studies of protein-small molecule interactions
Promotor: M. Ubbink, Co-promotor: G. Siegal
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Development of organ-on-a-chip systems for translational and personalized medicine
We have developed a microfluidic platform for complex 3D organotypic cell cultures (so-called organ-on-a-chip systems) which are suited for integration in 96 or higher well plate format.
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Imaging
The imaging group focuses on bio-imaging, image analysis and visualization.
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Software
Image-Pro Plus, ImageJ, Cell Profiler, R, Knime and NIS-elements
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LUMC Collegezaal 4
A 90+ seat room in the LUMC Main Building. Rolling, flexible, tables on a carpetted floor allows for the quiet re-arrangement of the room to support teaching in groups of many size. Nearly 3 full walls are covered in magnetized, writable surfaces, and there are hinged TVs on the walls which can be beamed…
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Bamboo
Biodiversity and trade: mitigating the impacts of non-food biomass global supply chains.
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Pair configurations to molecular activity coefficients: PAC-MAC
This thesis provides an overview of the development of the Pair Configuration to Molecular Activity Coefficient (PAC-MAC) model.
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Hai Lin
Science
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Jeshua Tromp
Faculteit der Sociale Wetenschappen
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Yumeng Wang
Science
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Jiahui Wang
Science
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Marjolein Fokkema
Faculteit der Sociale Wetenschappen
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Amelie Müller
Science
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Riccardo Mancinelli
Science
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Masha Medvedeva
Faculteit Rechtsgeleerdheid
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Tycho Jongenelen
Science
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Oda Nuij
Faculteit Archeologie
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Steven Miletic
Faculteit der Sociale Wetenschappen
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Xiaoyang Zhong
Science
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Stefano Merciai
Science
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Maria Yazdanbakhsh
Faculteit Geneeskunde
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Maarten van 't Riet
Faculteit Rechtsgeleerdheid
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Julian Karch
Faculteit der Sociale Wetenschappen
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Wil Tamis
Science
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Irlan Rum
Science
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Sebastian Fajardo Bernal
Science
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Interactions from lipid membrane deformations
Biological cells, the basic building blocks of all life forms, are surrounded by a lipid membrane. More than half of the membrane is occupied by membrane proteins, which can regulate the cell functionality through specific arrangements.
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‘Seeing voices’: the role of multimodal cues in vocal learning
Can birds - like people- ‘see’ voices and learn how to sing by listening and watching?
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Protein arginine methyltransferases as modulators of lipid metabolism and inflammation and the relevance for atherosclerosis
Acute cardiovascular clinical events such as myocardial infarction and cerebral stroke represent the major cause of death in Western societies. These pathologies are primarily resulting from atherosclerosis, a progressive condition characterized by the accumulation of lipids, immune cells, and fibrous…
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Weathering the Ice Age
Where did species survive the cold cycles of the current Ice Age?
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Ariane Briegel: 'AI literally opens new worlds for the life sciences'
Bacteria caught red-handed, deeply frozen just as they were about to cause Lyme’s disease. Ariane Briegel is wildly enthusiastic about the wonders she observes thanks to three elements: a freezing technique, a camera-equipped microscope, and AI. ‘It’s fascinating. Every single cell is different.’
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Global fitness maximising approaches to evaluate the trade-offs involved in the evergreen and deciduous conundrum
Which traits and/or trade-offs determine benefits of being deciduous or evergreen?
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Mimetas receives 5.2 million dollar investment for organ-on-a-chip
Venture capital investors Zeeuws Investerings Fonds and Participatiemaatschapij Oost Nederland have joined forces with national and regional partners to fund development and sales of MIMETAS’ unique 3D disease- and tissue modelling technologies.
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Predictive pharmacology
The aim of this research area is to be able to predict human drug response on the basis of mathematical models that are developed using preclinical experiments and prior knowledge.
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Statistical Science
The research programme Statistical Science is concerned with the analysis and interpretation of masses of data, the quantification of uncertainty using probability models, and the development and benchmarking of algorithms and methods with these aims.
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Stochastic resetting and hierarchical synchronisation
Stochastic resetting is simple enough to be approached analytically, yet modifies stochastic processes in a non-trivial way.
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Research
Research lines within the Pharmacy group: