207 search results for “antimicrobial steven” in the Public website
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Witnessing the Process of Bacterial Cell Death: Novel Antimicrobials and Their Mechanisms of Action
This thesis describes the antimicrobial discovery strategy developed in our group, the den Hertog Group at the Hubrecht Institute. It includes a cultivation-based screening approach for novel antimicrobial agents from the source of fungi, and a bacterial time-lapse imaging approach for antimicrobial…
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Quantitative pharmacology of antimicrobials
Antimicrobial drugs constitute a fundamental part of modern medicine. The global rise in antimicrobial resistance poses a major threat to global health.
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Anti-microbial and Anti-biofilm compounds From Indonesian Medicinal Plants
Promotor: C.A.M.J.J. van den Hondel, Co-promotor: Sandra de Weert
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Steven van der WerffFaculty of Social and Behavioural Sciences
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Steven Braber
University Facility Services
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Steven Hogg
ASSC
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Steven Claeyssens
Faculty of Humanities
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Steven MenijnExpertisecentrum Vastgoed
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Steven Maas
Faculty of Science
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Steven David
Faculty of Governance and Global Affairs
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Ecology-based discovery of novel antimicrobials from rare Actinobacteria
Uncover novel antimicrobials with prospective health benefits for sea turtles.
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Steven Hoogwout
ICLON
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Steven VreugdenhilICLON
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Conjugates and Natural Products as Next-Generation Strategies Against Antimicrobial Resistance
This thesis tackles the urgent challenge of antimicrobial resistance (AMR) through the design of novel antibacterial agents.
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Steven DenneyFaculty of Humanities
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Steven KunnenFaculty of Science
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Steven MiletićFaculty of Social and Behavioural Sciences
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Steven HagersFaculty of Humanities
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Steven BruintjesFaculteit der Rechtsgeleerdheid
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Steven van der Werff
Social & Behavioural Sciences
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Steven de Rooij
Faculty of Science
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Steven van Egmond
Faculty of Science
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Steven de Wit
ISSC
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Steven TruxalFaculteit der Rechtsgeleerdheid
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Steven LauritanoFaculty of Humanities
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Steven van HeijningenLeiden University Libraries
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Steven van WijkFaculty of Social and Behavioural Sciences
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Floor StevensFaculty of Science
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Yves Stevens
Faculteit der Rechtsgeleerdheid
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James Stevens
Faculty of Science
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Sarah StevensFaculty of Social and Behavioural Sciences
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Steven Salaita - An Honest Living: Stories from Inside and Out of Academe
This lecture has been cancelled.
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Anthracycline biosynthesis in Streptomyces: engineering, resistance and antimicrobial activity
Actinobacteria are well known for the production of bioactive natural products, many of which have applications in the fields of human, animal and plant health. Subject of this thesis are the anthracyclines, glycosylated aromatic polyketides with potent anticancer activity.
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Unraveling the drivers of antimicrobial pharmacokinetic variability in individuals with obesity and hospitalized patients with multimorbidity
Obesity may alter how a person absorbs, distributes, metabolizes or excretes medication. This thesis describes how obesity affects drug levels in the blood for antimicrobial agents, such as ciprofloxacin and fluconazole.
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Nathaniel Martin in podcast about antimicrobial resistance
Professor Biological chemistry Nathaniel Martin from the Institute of Biology Leiden is interviewed by the Netherlands Innovation Network on innovative scientific approaches. He talks about his work on designing new antibiotics and developing new molecules to make resistant bacteria susceptible again…
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Next generation bacitracin: reimagining a classic antibiotic
Given the accelerating appearance of antimicrobial resistance, there is an urgent need for more fundamental research into novel antibiotic strategies. The work in this thesis helps to address this global problem by developing new antibiotic compounds, inspired by the antibacterial mechanisms of the…
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Regulation of autophagy-related mechanisms during bacterial infection
Autophagy is a fundamental degradative process, maintaining cellular homeostasis and functions in host defense against intracellular pathogens, including mycobacteria and Salmonella.
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Mariana Avalos GarciaFaculty of Science
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Marc Stevens and colleagues reveal weak spot in internet security
Marc Stevens, PhD student of Ronald Cramer, and colleagues have found a weak spot in internet security. As a consequence of this weak spot in the infrastructure of digital certificates forged certificates can be issued that can be fully trusted by the usual web browsers. The results have been presented…
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Meiling GaoFaculty of Science
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Semisynthetic glycopeptide antibiotics
Vancomycin is a last-resort antibiotic for the treatment of many Gram-positive bacterial infections, while remaining inactive against Gram-negative strains.
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Volatile compounds from Actinobacteria as mediators of microbial interactions
Streptomyces are bacteria abundant in soil that participate in diverse and complex interactions. These bacteria are the main producers of the antibiotics we currently use in the clinic.
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Microbial Sciences
In the research programme Microbial Sciences we perform state-of-the-art research in the field of biotechnology and microbial sciences.
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What are we defending? Steven Pinker on the core values of NATO and the Enlightenment
NATO not only safeguards our security and stability, but also defends Enlightenment principles, promoting prosperity, health and freedom. This is what eminent psychologist and thinker Steven Pinker argued to a packed Great Auditorium.
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Nicola ThomeFaculty of Science
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Projects
An overview of Quantitative Pharmacology projects
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Quantitative Pharmacology
The Quantitative Pharmacology group headed by Coen van Hasselt focusses on the application of state-of-the-art quantitative pharmacometrics and systems pharmacology modeling combined with translational experimental models to develop personalized treatment strategies for antibiotics and to combat antimicrobial…
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Key publications
Key publications of the Antiviral Pharmacology group.
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Environmental and metabolomic study of antibiotic production by actinomycetes
Promotor: Prof.dr. G.P. van Wezel
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