8,468 search results for “development ” in the Public website
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Development of a universal delivery system for tailor-made cancer vaccines
The potential of liposomal cancer vaccines
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Development of hyaluronan-based dissolving microneedle arrays for dermal vaccination
Dissolving microneedles are a subgroup of microneedle types that completely dissolve within the skin. During this dissolving process the vaccine, stored in the needle matrix, is released into the skin.
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Religion, Class, and the Postwar Development of the Dutch Welfare State
Religion, Class, and the Postwar Development of the Dutch Welfare State. Dennie Oude Nijhuis.
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European foreign policy in times of crisis: a political development lens
EU foreign policy has become increasingly politicised over the past years, amongst others as a consequence of the succession of crises. Crises may engender processes of crisis framing and contestation. This article focuses on how the policy demands being voiced in these processes of contestation are…
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Profile 6. Developing a parcel based historical GIS of the Netherlands
Historical geo data are gaining in importance. Provided that they are exactly geo referenced, they can be stored into a GIS and thus be combined with all kinds of maps (topographical, pedological, etc.) and datasets. This makes it possible to analyze historical developments in space and time on a detailed…
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Design and development of conformational inhibitors and activity-based probes for retaining glycosidases
Glycosidases are essential in fundamental biological processes and are responsible for the degradation of most (oligo)saccharides, glycolipids and glycoproteins.
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The historical development of the Dutch posture-verb progressive construction
On the 22nd of February, Ami Okabe successfully defended a doctoral thesis. The Leiden University Centre for Linguistics congratulates Ami on this achievement!
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Development of a Transgenic Mouse Model to Study the Immunogenicity of Recombinant Human Insulin
Mouse models are commonly used to assess the immunogenicity of therapeutic proteins and to investigate the immunological processes leading to antidrug antibodies. The aim of this work was to develop a transgenic (TG) Balb/c mouse model for evaluating the immunogenicity of recombinant human insulin (insulin)…
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T-CYCLE EPR: Development at 275 GHz for the study of reaction kinetics & intermediates
A difficulty of studies on chemical kinetics are the reaction time scales and detection of their intermediates.
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Developing metabolomics for a systems biology approach to understand Parkinson's disease
Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…
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Linda van Leijenhorst
Faculteit der Sociale Wetenschappen
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Stefanie van EsveldFaculty Governance and Global Affairs
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Eduard KlapwijkFaculteit der Sociale Wetenschappen
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Harriet VermeerFaculteit der Sociale Wetenschappen
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WARN-D: developing an early warning system for depression in students
My ERC Starting Grant, funded with €1.5 million for 5 years as part of the Horizon 2020 research and innovation program, is focused on building the early warning system WARN-D to reliably forecast depression in young adults before it occurs. Why depression, and why prediction?
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About the programme
To maximise your personal development, we ensure tutorials are small-scale and staff members extremely accessible. In year one, you’ll have an average of 12 contact hours, half of which comprise lectures (in English) and the remainder tutorials (optionally Dutch or English).
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Develop a methodology for assessing the effective dose of nanomaterials for environmental risk assessment purposes
How to make a quantitative assessment of the relative contribution to toxicity of ions and particles? Is the toxicity of nanoparticles related to their size or shape? Which physicochemical property of nanoparticles is an appropriate dose metric of nanoparticles?
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RE-PAIR: Unravelling the Impact of Emotional Maltreatment on the Developing Brain
What role do parent-child interactions play in the development, maintenance and treatment of depression in young people?
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The Development of the Pivot State Concept Based on Mackinder’s Heartland Theory
The research addresses the question of “what is the impact of geopolitical changes to the pivot states in the Middle East? With special focus on Turkey, Iran and Saudi Arabia.”
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fingerprint biomarkers to guide antibiotic therapy and reduce resistance development
Ontwikkeling van resistentie tegen antibiotica kan optreden als patiënten onnodig of te lang met antibiotica behandeld worden. Diagnostiek waarmee snel een bacteriële infectie vastgesteld kan worden, of de response op antibiotica bepaald kan worden, zijn daarom belangrijk om therapie te optimaliseren…
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Development of Machine Learning-Derived Digital Biomarkers for Trial@Home Clinical Trials
PhD defence
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Common Practice: a livelihood perspective of economic development in the post-Roman world.
Today’s socio-economic challenges aren’t new. In the centuries after the retreat of the Roman state people with different backgrounds and with different ways of life somehow managed to build and maintain a complex economic system in northern Gaul that would produce the ruling dynasties of Europe. By…
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Development of highly accurate density functionals for H2 dissociation on transition metals
Metals surfaces form a group of effective catalysts for the reaction of small molecules such as hydrogen (H2).
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Contact
Contact us about initial teacher education, educational research and teacher professional development
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indigenous institution in the context of sustainable socio-economic development in Indonesia
In times of hardships or crisis, local people know how to deal with it using their resourcefulness. Although efforts are sometimes made by the government to help them, they are fully aware that community support is at least equally important.
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SATURN: Developing Solutions for Underwater Radiated Noise – Sound impact on migratory fishes
Do natural soundscapes affect migratory decisions of fishes moving up and down rivers and is this process disturbed by vessel sounds?
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Maedeh NasriFaculteit der Sociale Wetenschappen
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Susanne KamerlingFaculty Governance and Global Affairs
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Caroline ArchambaultFaculty Governance and Global Affairs
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Play by the rules? : coordination of EU sustainable development policies and the importance of the politico-legal context
There is an increasing amount of attention on EU and its Member States contributions to implementation of two landmark agreements: the Paris Climate Agreement and the UN Agenda 2030 with Sustainable Development Goals (SDGs). Absent from the current literature is an analysis of the political effect of…
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Opening Minor Sustainable Development
The new CML minor Sustainable Development started on Monday 7 September 2009 with an official opening by the Vice-Rector Prof. Rietje van Dam.
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Development of Cost efficient Advanced DNA-based methods for specific Traceability issues and High Level On-site applications
Schneider
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Knowledge development of secondary school L1 teachers on concept-context rich education in an action-research setting
This thesis reports on a study that examined the development of L1 teachers’ practical knowledge when they researched and implemented concept-context rich education in an action-research setting.
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Subang: An Indigenous Institution for Sustainable Community-Based Development in the Sunda Region of West Java, Indonesia
This study attempts to understand how indigenous community institutions pose an important role in sustainable community-based development, including the integration between local culture and development.
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and Pains of Polysemy: Maritime Trade, Averages, and Institutional Development in the Low Countries (15th–16th Centuries)
The Power and Pains of Polysemy: Maritime Trade, Averages, and Institutional Development in the Low Countries (15th–16th Centuries) investigates the development of General Average and other so-called Averages in the Low Countries on the eve of the early modern period, showing how the various varieties…
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Surya Tjandra defends his Ph. D thesis ‘Labour Law and Development in Indonesia’ on 4 February 2016
In his thesis Tjandra analuses the development of labour law in Indonesia. He focusses on the developments after the fall of the Soeharto regime (1998), the so called reformasi period.
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The role of hearing signers in the development of channel specific structures in sign languages of deaf communities
In this project, the hypothesis that language contact crucially impacts the development of spatial grammar and phonology is investigated.
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Meta‐modelling: development of methods and tools for the exchange, analysis and communication of anonymised patient data
This project is a collaboration between Sanquin, LUMC and LIACS. It focuses on the development of meta-modelling methods and tools for the exchange, analysis, and publication of anonymised patient data. Measures are being constructed to evaluate both the level of privacy and the extent to which an anonymized…
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Conceptualisation of the Rule of Law in its External Relations: Case Studies on Development Cooperation and Enlargement
On 26 June 2019, Lisa Louwerse defended her thesis 'The EU’s Conceptualisation of the Rule of Law in its External Relations: Case Studies on Development Cooperation and Enlargement'. The doctoral research was supervised by Prof. C.A.P. Hillion.
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The role of hearing signers in the development of channel specific structures in sign languages of deaf communities
In this project, the hypothesis that language contact crucially impacts the development of spatial grammar and phonology is investigated.
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The development of the speech production mechanism in young children: evidence from the acquisition of onset clusters in Dutch
On October 31st, Margarita Gulian succesfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Margarita on this great result.
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Development of Quantitative Nanostructure Activity Relationship (QNAR) Models Predicting the Toxicity of Metal-based Nanoparticles to Aquatic
Describe and identify what dosimetry parameters are of importance to interpret dose-response relationships (eg., mortality, sub-lethal, growth or reproduction inhabitation, DNA damage and reactive oxygen species, etc. ) for metal-based nanoparticles? How to develop quantitative models that enable to…
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Labor movements and party system development: Why does the Caribbean have stable two-party systems, but the Pacific does not?
How can we explain that Caribbean small states have the most stable two-party systems in the world, while Pacific small states have either very weak parties or no parties at all? Matthew Louis Bishop (University of Sheffield, UK), Jack Corbett (University of Southampton, UK) and Wouter Veenendaal (Leiden…
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Development of an intradermal tuberculosis vaccine by combining dissolvable microneedle arrays and Mycobacterium tuberculosis antigen-containing
Mycobacterium tuberculosis (Mtb), the pathogen causing tuberculosis (TB), is the leader among all pathogens responsible for the most human deaths today and it is considered as one of the top 10 causes of death worldwide. There is an increasing occurrence of multidrug-resistant and even totally drug-resistant…
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Reverse engineering the role of tip cells and pericytes in vascular development
Promotor: Prof.dr. R.M.H. Merks
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Development of an effective, safe, and painless intradermal tuberculosis vaccine based on microneedles loaded with antigen-containing nanoparticles
Tuberculosis (TB) is a major global health problem caused by the bacterium Mycobacterium tuberculosis (Mtb). In 2015, there were estimated to be 10.4 million new cases and 1.8 million deaths ascribed to TB, making it one of the top 10 causes of death worldwide. Unfortunately, the only current registered…
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Things Change: Black Material Culture and the Development of a Consumer Society in South Africa, 1800-2020
This book is the first systematic analysis of the changes in the use of goods and services by households of Black South Africans since the early nineteenth century.
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The road to drain or gain: Dutch private investment and economic development in late colonial and early independent Indonesia
On 20 September 2023 Mark van de Water successfully defended a doctoral thesis and graduated.
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Strategic research into and development of best practice for, predictive modelling on behalf of Dutch Cultural Resource Management
Are predictive archaeological maps a reliable tool to play an important role in the spatial planning? One of the goals of this project was to develop best practices for the production and application of the models.
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The role of zebrafish (Danio rerio) larvae in developing new drug candidates for treating anxiety, from natural sources
Can zebrafish larvae be used as a behavioural model for screening natural products as potential neurotropic drugs?