752 search results for “safety” in the Public website
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Multi-objective Evolutionary Algorithms for Optimal Scheduling
Multi-objective optimization is an effective technique for finding optimal solutions that balance several conflicting objectives. It has been applied in many fields of our world, because practical problems usually have more than one desired goal. For example, developing a new vehicle component might…
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Development of a Kidney-on-a-Chip Model for Compound Screening and Transport Studies
Pharmaceutical companies, governments and the general public have become increasingly aware that animal models used in drug testing lack vital aspects to serve as an accurate representation of human biology. As models of the human body should become more physiologically relevant, animal models no longer…
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Quality-driven multi-objective optimization of software architecture design: method, tool, and application
Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M.R.V. Chaudron, Co-Promotor: M.T.M. Emmerich
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SCALES project
How to strike a balance between the sometimes conflicting stakes of individual, public and private data-producers and data-processors?
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Novel analytical approaches to characterize particles in biopharmaceuticals
Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).
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Discoveries in 2023
From nanoparticles to colliding ice planets and from biological origami to new x-ray scanner techniques: this year again, our scientists have made wonderful discoveries. From the largest numbers to the smallest molecules and from the oldest galaxies up to the latest algorithms, take a look at each institute's…
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Overview
Our research is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.
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Development of Cost efficient Advanced DNA-based methods for specific Traceability issues and High Level On-site applications
Schneider
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Host community compensation
Can the offering of host community compensation help to prevent or solve siting controversies, and if so, why and under which conditions?
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Gendered impacts of industrial logging
This study focuses on the local level impacts of a highly globalised industry: the international trade in tropical timber.
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Legal Perspectives on the Cross Border Operations of Unmanned Aircraft Systems
On 14 November 2019, Luis Fiallos Pazmino defended his thesis 'Legal Perspectives on the Cross Border Operations of Unmanned Aircraft Systems'. The doctoral research was supervised by Prof. P.M.J. Mendes de Leon and Prof. E.C.P.D.C. De Brabandere.
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Poly-(lactic-co-glycolic-acid)-based particulate vaccines: particle uptake by dendritic cells is a key parameter for immune activation
Poly(lactic-co-glycolic acid) (PLGA) particles have been extensively studied as biodegradable delivery system to improve the potency and safety of protein-based vaccines. In this study we analyzed how the size of PLGA particles, and hence their ability to be engulfed by dendritic cells (DC), affects…
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Focal Areas
Our research at CWTS is organized in three focal areas. These focal areas represent our core areas of interest, as defined in our knowledge agenda for the period 2023-2028.
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Prediction of the potency of mammalian cyclooxygenase inhibitors with ensemble proteochemometric modeling
Source: J Cheminform, Volume 7, Issue 1 (2015)
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Vision
The Pharmacy research group focusses on the development of predictive models to improve clinical drug efficacy and safety. We work on clinical problems that require further mechanistic understanding and strive for ultimate benefit to patients.
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Editorial: Sanity and Resilience in Times of Corona
This editorial to RHCPP discusses how COVID-19 can be seen as a 'creeping crisis' according to the authors of its lead article (Boin et al, 2020) and how resilience may depend on the real heroes behind the scenes of response to disaster and adversity.
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A blessing in disguise?! Discretion in the context of EU decision-making, national transposition and legitimacy regarding EU directives
This dissertation looks into the role of discretion granted by EU directives (Article 288 Treaty on Functioning of the European Union) in legislative decision-making and national transposition processes of these directives.
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Our vision of diversity
Leiden University endorses inclusiveness and diversity. It is open to all those who wish to study or work here, and to develop their full potential. The University is an open community where everyone who wants to contribute to its ambitions and to all that it stands for will feel at home and have equal…
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Why Leiden University
In an increasingly complex and security-challenged society, the CSM programme, Intelligence and National Security, provides you with the theoretical and practical skills to understand the issues underlying security challenges and develop solutions for crisis and security management.
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Why Leiden University?
In an increasingly complex and security-challenged society, the CSM programme, Cybersecurity Governance, provides you with the theoretical and practical skills to understand the issues underlying security challenges and develop solutions for crisis and security management.
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Why Leiden University?
In an increasingly complex and security-challenged society, the CSM programme, Governance of radicalism, extremism and terrorism, provides you with the theoretical and practical skills to understand the issues underlying security challenges and develop solutions for crisis and security management.
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Why Leiden University
In an increasingly complex and security-challenged society, the CSM programme, Governance of crisis, provides you with the theoretical and practical skills to understand the issues underlying security challenges and develop solutions for crisis and security management.
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Why Leiden University
n an increasingly complex and security-challenged society, the CSM programme, Governance of Violence, provides you with the theoretical and practical skills to understand the issues underlying security challenges and develop solutions for crisis and security management.
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Why Leiden University?
blabal
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Leadership Labs
In the Leadership Lab (4 EC) you tackle a topical problem presented by one of our partner organisations and develop important leadership skills in practice.
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Affinity
Designing and synthesizing high-affinity ligands for a given drug target have always been among the more important challenges in the drug discovery process.
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Protest in Wijnhaven building has ended
Everything is peaceful again in and around the Wijnhaven building at Campus The Hague. Earlier today, the location was the scene of a large pro-Palestinian protest. Lectures were cancelled. In the end, everyone left the building voluntarily.
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Career preparation
Leiden University offers you several services related to career orientation and job application skills.
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Prepare for your studies
You’ve been accepted! Leiden University looks forward to welcoming you as a new student. Your next step is to prepare for your studies. Below you can find some tips to help you get a head start as you embark on your studies at Leiden University.
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Extra curricular
Are you interested in taking up an extra challenge during your master’s programme? Have you thought about applying for our Summer School programme or are you interested in developing your personal leadership style?
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Career prospects
Many students receive their first job offer during or right after their Business Studies internship. After graduating you can also aim for a career in Bio-Pharmaceutical research.
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‘International isolation is not an option’
Security in the broadest sense of the word was the key focus in the Interfaculty Conference on 4 April in Leiden. With almost 200 attendees and such well-known speakers as Dick Schoof, Pieter van Vollenhoven and Ad Verbrugge, the first conference was a success.
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Graig Klein awarded an ERC Starting Grant
Graig Klein, assistant professor at the Institute of Security of Global Affairs (ISGA), has been awarded a Starting Grant by the European Research Council (ERC) for his project TERGAP. With this 1.500.000 euro grant Klein and his research team will investigate terrorist groups’ decision-making and strategic…
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Admission requirements
To be eligible for MSc Crisis and Security Management at Leiden University, you must meet the following admission requirements.
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Admission requirements
To be eligible for MSc Crisis and Security Management at Leiden University, you must meet the following admission requirements.
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Cyber security
To make digital communication more secure, we need to tighten up the legal frameworks and identify the biggest cyber threats.
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DNAmarkerpoint
The main purpose of DNAmarkerpoint is to better understand the ecology, evolution and biodiversity through the study of ancient- and modern DNA.
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Starter grant 1
Project Announcement: ‘EU human-centered digital transformation’ (2023 – 2027) funded by Leiden University Starting Grant In Spring 2023, Simona Demková and Daniel Mândrescu from the Europa Institute secured the new Leiden University Starting Grant, valued at 240,000 EUR, for a collaborative project:…
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Vascular and Regenerative Medicine
Methods of treatment for chronic illnesses are limited. Doctors and researchers at Leiden University Medical Center (LUMC) and Leiden University are working on new therapies as an alternative for organ transplants. The goal is to cure the illnesses by restoring organs to their original function. Stem…
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Rent our Lab
Psychology Lab on Wheels is available for rent for your on-site research. What does the mobile lab look like? What are the requirements? How do you make good use of the mobile lab?
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Why Leiden University?
Leiden University enjoys an excellent worldwide reputation, built on over four centuries of outstanding teaching and research. The university has two locations: Leiden and The Hague. Our Urban Studies programme is located in The Hague, international city of peace and justice and the ideal environment…
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Image-based Computational Biology
In this research group, led by Dr. Joost Beltman, the aim is to employ mathematical and computational dynamical modelling approaches in order to quantitatively and mechanistically understand the dynamical behaviour and regulation of intracellular networks of genes, proteins and metabolites as well as…
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Dennis Broeders in the Dutch newspaper Volkskrant about the national failure of number 112
Emergency services and governments were caught by surprise on Monday 24 June by the nationwide breakdown of the emergency phone number 112. The breakdown raises the following question: ‘Could this not have been prevented’?
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Responsible research with animals
Animal experiments are not undertaken lightly; we are working with sentient beings. As scientists, we have great responsibility to handle laboratory animals with care. Read here how we consider and justify this.
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LIFE-GREENAPI
Development & demonstration of low environmental impact innovation and optimization practices in pharma production.
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Young Faculty and Interfaculty Lunches
YAL organises young faculty lunches at all Leiden University faculties. Additionally, we organise young interfaculty lunches to bring together young academics from across the university.
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Education
The programmes offered by the Faculty of Governance and Global Affairs in The Hague are closely linked to the defining image of The Hague as a city of international justice, peace and security as well as the centre of Dutch public administration and international governance.
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Determining the kinetic profile of ENT1 inhibitors
Supervisor: Anna Vlachodimou
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Training and certification
An important aspect of the promotion and safeguarding of good practices at the Institute of Psychology is to make sure that employees are being facilitated and guided by offering information about and resources for training. On this page, an overview of various mandatory and recommended training is…
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Research
Knowledge on how to adjust a drug dose in special patient populations such as (prematurely born) neonates or children, obese individuals or critically-ill patients, is not only crucial for novel compounds, but also for existing drugs which are often used in an off-label manner in these special patient…