3,207 search results for “this week s discoveries” in the Public website
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Inhibitor Selectivity: Profiling and Prediction
Less than 1 in 10 drug candidates that enter phase 1 clinical trials actually gets approved for human use.
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Pascal chair 2023
Peter Flach is Professor of Artificial Intelligence at the University of Bristol. An internationally leading scholar in the evaluation and improvement of machine learning models using ROC analysis and calibration, he has also published on mining highly structured data, on knowledge-driven and explainable…
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Finding and valorizing new antibiotics using AI
Antibiotics are a class of medicine most people take for granted. But pathogenic bacteria are becoming more and more resistant to our antibiotics, and this poses a great challenge for future treatments. There is thus a great societal need to identify new molecules that can address new targets and be…
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Programme structure
The Drug Discovery and Safety specialisation consists of compulsory and optional components.
- Leiden Science in 2023
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Organisation
The Leiden Academic Centre for Drug Research (LACDR) is responsible for the research and education in Bio-Pharmaceutical Sciences carried out at Leiden University.
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Night of Discoveries with Leiden University researchers and fun activities
Festival
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‘Be open to other cultures’
This week more than 400 international students are starting their study programme in Leiden or The Hague. Why did they choose to study here? And what is the advice from their mentors?
- Contact
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History
Life Sciences Artificial Intelligence Data Science
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Leiden welcomes international students
If you're in Leiden this week, you can't miss the large groups of international students exploring the city. The Orientation Week Leiden (OWL) - the twice-yearly introduction week for international students - started on Tuesday 24 January, this time with more than 400 new students. ‘Every second building…
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Glycoproteomics assays for prostate cancer biomarker discovery
PhD defence
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Novel immunomodulatory drugs for tuberculosis treatment
Can drugs that target host signaling pathways be used to eradicate antibiotic-resistant bacteria?
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Oncode Accelerator
Providing each cancer patient with the right treatment remains a challenge. Oncode Accelerator aims to change this by innovating the way we develop cancer treatments, thus ensuring the patient is at the heart of the process. Leiden University, the LUMC and other partners will implement this new way…
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LED3 PhD-Postdoc Symposium 2024
Conference
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Pursuing new anti-cancer therapy as a team
Cancer is the leading cause of death in the Netherlands, and, with over 100 different types of cancer, it’s not a simple disease. Today, skin, breast, lung, prostate and colon cancer are the most diagnosed forms. Therefore, the discovery and development of new drugs has the ability to significantly…
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Determining the kinetic profile of ENT1 inhibitors
Supervisor: Anna Vlachodimou
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Leiden Academic Centre for Drug Research
The Leiden Academic Centre for Drug Research (LACDR) is a centre of excellence for multidisciplinary research on drug discovery and development.
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Teaching
At Molecular Physiology we teach the following courses within the Leiden Institute of Chemistry's Chemistry and Life Science and Technology programmes.
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The Phantom of the Ego: Modernism and the Mimetic Unconscious
The Phantom of the Ego is the first comparative study that shows how the modernist account of the unconscious anticipates contemporary discoveries about the importance of mimesis in the formation of subjectivity.
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Clavis Aurea? Structure-enabled approaches of identifying and optimizing GPCR ligands
Promotores: A.P. IJzerman, H.W.T. van Vlijmen
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Quantitative pharmacological modelling for optimizing treatment of sepsis
Sepsis is a life-threatening condition caused by a dysregulated host response to infection, it is associated with significant morbidity, mortality, and with a high financial burden on global healthcare systems. Bacterial infections are the primary cause of sepsis, but the growing prevalence of antimicrobial…
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The Complete Archaeology of Greece
This book covers the story of Greece and its central role in our understanding of European civilization, from the Palaeolithic era (400,000 BP) to the early modern period (1950 AD).
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Translational pharmacokinetics-pharmacodynamics in zebrafish: integration of experimental and computational methods
The zebrafish is a promising vertebrate model organism in early drug discovery and development.
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Zebrafish embryos and larvae as a complementary model for behavioural research
Promotor: Prof.dr. M.K. Richardson
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Targeting the adenosinergic system
Adenosine is an endogenous ligand which exerts its action by activating adenosine receptors (ARs), while its circulating levels are controlled via a variety of mechanism and proteins, amongst others the equilibrative nucleoside transporters (ENTs).
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Key publications
Key publications of the Computational Drug Discovery group
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Contact
Do you have questions about the Bio-Pharmaceutical Sciences master’s programme or the specialisation Drug Discovery and Safety? Please contact us.
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Unraveling temporal processes using probabilistic graphical models
Real-life processes are characterized by dynamics involving time. Examples are walking, sleeping, disease progress in medical treatment, and events in a workflow.
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Calling alumni from Brussels: ‘It's very important to vote’
They dreamed of Brussels, worked hard and finally succeeded: working for Europe. The list of Leiden University alumni in Brussels is long. Julia Gencheva and Vincent Míča talk about their jobs in Brussels and urge everyone to vote. ‘The decisions also affect your daily life.’
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Queen Máxima inspects zebrafish embryos
On Wednesday the 4th of September, Queen Máxima opened the renovated tropical greenhouse complex of the Leiden Hortus Botanicus. At the occasion Máxima met with IBL-PhD student Mahin Ghorbani from Iran and talked with her about her work on drug discovery from Iranian medicinal plants using zebrafish…
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Career preparation
During the programme we will prepare you for your career as a legal professional in a global legal environment. Read more about the career preparation activities
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The History of the Arabic Script: New Discoveries and Developments
Lecture, Workshop
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Leiden master's student in Labour Law is ‘student intern of the week’ in Dutch magazine Mr.
Eva Lammers is currently studying for a master's degree in labour law at Leiden University and expects to graduate in autumn 2023. Lammers did her internship at law firm JPR in Deventer and was thrown in at the deep end from the start. 'Assignments aren’t arranged for you, you've got to arrange them…
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Biological and Soft Matter Physics
Research groups in the Biological & Soft Matter Programme unravel mechanisms in biological processes and develop novel bio-inspired soft materials.
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Meet the professor in The Hague
Leiden University's professors will be going to elementary schools again to teach about science and research. During the class discovery-based learning will be central. The professors will go to several schools in The Hague. The classes are part of the university's celebration of its 445th birthday…
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Bio-organic Synthesis
The research in the Biosyn group is focused on the design, synthesis and function of the four major types of biomolecules: nucleic acids, carbohydrates, peptides and lipids and hybrid structures thereof. These biomolecules and their derivatives are used in drug discovery and chemical biology, to develop…
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Chemical Probe Facility
The Chemical Probe Facility is part of the Leiden Early Drug Discovery & Development (LED3) center. Activity-based protein profiling (ABPP) is one of the pillars of chemical biology. ABPP determines the activity of entire protein families in living cells and tissues under physiological conditions, such…
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The Dakhleh Oasis Project
Update : March 2020 A.J. Mills
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specialist Ton Koopman returned to the San Francisco Symphony for two weeks
Leiden University Professor and world renowned Bach specialist Ton Koopman returned to the San Francisco Symphony for two weeks of concerts celebrating J.S. Bach and his legacy.
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Computational Network Science Lab
The Leiden Computational Network Science Lab (CNS Lab) researches methods for knowledge discovery from real-world network data.
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Formation of synthetic fuel: new insights!
Navarro Paredes
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Projects
The Young Academy Leiden and its workgroups have launched different initiatives in the interest of early-career scholars. Read all about the different projects of the Young Academy Leiden here.
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Microvasculature in Microfluidics: matching complexity with compatibility
In vitro disease models play a fundamental role in drug research. They enable the systemic identification and validation of disease mechanisms and the discovery of possible drug targets. However, more than often, drug candidates that are identified in vitro fail in the later clinical stages of drug…
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Applied String Theory: Explaining Quantum Matter with Black Holes
Schalm
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Quantitative systems pharmacology modeling of biotherapeutics in oncology
In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.
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Island Networks
The focus of this programme is the inter-community social relationships and transformations of island networks in the Lesser Antilles across the historical divide.
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Discovering the preference hypervolume: an interactive model for real world computational co-creativity
In this thesis it is posed that the central object of preference discovery is a co-creative process in which the Other can be represented by a machine. It explores efficient methods to enhance introverted intuition using extraverted intuition's communication lines.
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Grants & Awards
Grants awarded to molecular physiology research
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Small-molecule inhibitors of bacterial metallo-β-lactamases
The main focus of the thesis is the discovery and development of novel inhibitors of bacterial metallo-β-lactamases (MBLs).