23 search results for “cannabis” in the Public website
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Cannabis makes you less alert
Regular users of cannabis are less aware of their own mistakes, and they are not good at creative thinking. This is the conclusion drawn by psychologist Mikael Kowal from his research on the effects of cannabis. PhD defence 6 October.
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The molecular secrets of medicinal cannabis
Chronic pain, nausea or vomiting due to chemotherapy. If you suffer from such ailments, medicinal cannabis can be a godsend. Though a downside is that it can make patients high. Therefore, Leiden researchers from the Oncode Institute are investigating alternatives that do not make you high. In Nature…
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The body's own marijuana as inspiration for drug research
Endocannabinoids - the body's own marijuana - are promising departure points for drug research. Professor of Molecular Physiology Mario van der Stelt examines whether inhibiting their production can be a way to fight inflammatory brain disease and to combat obesity. Inaugural lecture 19 October.
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Molecular Physiology
Molecular Physiology is a research group at the Leiden Institute of Chemistry dedicated to the design, synthesis and application of chemical tools to study important biological and biomedical questions. The group is headed by Prof. Dr. Mario van der Stelt and includes the research lines of Assistant…
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Pain relief without the high
Researchers at Leiden University led by Mario van der Stelt (Leiden Institute for Chemistry) have set ‘gold standards’ for developing new painkillers based on the medicinal effects of cannabis. Publication in Nature Communications.
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Body's own marijuana helps us forget traumatic memories
The endogenous compound anandamide – often referred to as the body’s own marijuana – plays a role in erasing memories of a traumatic event. This was discovered by an international team led by Leiden chemist Mario van der Stelt. The results have been published in Nature Chemical Biology and may provide…
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Research
The current projects of the Molecular Physiology group focus on proteins of the endocannabinoid system, kinases and antibacterial targets. MSc- and BSc-students can contact Jessica van Krimpen-Kraaijenoord to apply for research internships.
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Young Hae Choi
Associate professor at the Natural Products Laboratory, Institute of Biology, Leiden University - the Netherlands
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Systems pharmacology of the endocannabinoid system
In this thesis, a system pharmacology approach, integrating metabolomics, pharmacology and chemical biology, was applied to understand and modulate the endocannabinoid system across different model systems (cells, zebrafish, mice and humans).
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Cannabinoid receptor 2 as a ‘drugable’ target: kinetic profile of novel receptor ligands
Supervisor: Andrea Martella
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Profiling programme about body’s own marijuana brings institutes together
Bringing together institutes and research groups, how do you do that? The Faculty of Science set up a joint research theme and financed three PhD positions. After four years, the profiling programme Endocannabinoids expires. ‘It really brought us together, and the collaborations remain.’
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Landmark ruling on tolerance agreements for Dutch ‘coffeeshops’
PhD candidate Demy Jongkind and Associate Professor Annemarie Drahmann – both part of the Department of Constitutional and Administrative Law – have been interviewed by the Kenniscentrum Europa Decentraal (KED) on the Dutch Services Act (DW) and cannabis tolerance policy.
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Discovering and developing drugs
Improving healthcare with our scientific discoveries: that is the goal of pharmaceutical research at Leiden University. And there’s a lot involved in that. Our research starts with the discovery of the effect achieved by a particular substance, and sometimes continues all the way through to the development…
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Beryl ter Haar participates in guest lecture at Kutafin State Law University Moscow
On Tuesday 22 January 2019, Beryl ter Haar participated in a comparative law lecture featuring labour law cases of the constitutional court of South Africa at the Kutafin State Law University Moscow, Russia. Topics discussed included short term employment contracts, the right to strike and the right…
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Marieke Liem in The Economist on drug-related murders in Europe
Marieke Liem, professor at ISGA, discusses how the number of drug-related murders has not decreased in the last years
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Euthanasia as a legal question
In the Netherlands, euthanasia has no longer been a criminal offence since 2002. The practice is governed by very strict conditions. Nonetheless, the legal issues surrounding it are still the focus of heated discussion, according to Leiden professors. They are discussing the issue on 18 March during…
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Student mental health problems still common but less so than in covid year 2021
The number of students suffering from stress and anxiety has decreased slightly compared with 2021. But around half still suffer from mental health problems. This is according to the National Mental Health and Substance Use Monitor.
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Mario van der Stelt appointed Professor of Molecular Physiology
Mario van der Stelt has been appointed Professor of Molecular Physiology at the Leiden Institute of Chemistry with effect from 1 November 2017.
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LIBC MRI Methods Meeting
Lecture
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Amanda Henry’s Leiden Experience: ‘I want to know why our ancestors made certain choices’
Two years ago, Amanda Henry joined the Faculty of Archaeology’s Archaeological Sciences department. She investigates diet and human evolution, with a specific focus on plant foods. ‘Most of the studies on the prehistoric diet focus on meat and hunting. This just didn’t make sense to me.’
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Little proof that doping really works
The list of substances prohibited by the World Anti-Doping Agency (WADA) is huge. PhD candidate Jules Heuberger looked at many of these, as well as at the methods used to detect them. He concluded that for very few of these substances is there is evidence that they actually do enhance performance. PhD…
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Social Science Matters: Confidence in the future?
After a long period of formation, the Rutte III cabinet presented itself on 26 October 2017. The coalition agreement on which ministers will build is called ‘Vertrouwen in de toekomst’ ('Confidence in the future'). But what impact will this new cabinet have on our future? We asked our researchers in…
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Hall of Fame 2020
In 2020, many of our staff and students have again won prestigious prizes and been awarded important research subsidies.