How has early development in R. ocellatus been modified as a result of its parasitic embryonic lifestyle?

What are the biological effects of Chinese herbal medicine in regulation of cancer cell metastasis?

We have examined sequences from the ligand-binding domain of the nicotinic acetyl choline receptor (nAChR) in 148 vertebrate species. We are in interested in this receptor because the α-neurotoxins of many venomous snakes binds to this receptor in its location at the neuromuscular junction in all ve…

A three-volume standard work on galls in Europe. Author Johannes C. (Hans) Roskam is associate professor emeritus in Evolutionary Biology and currently guest at Leiden University.

This dissertation presents the first full grammatical description of bago ts'amakkilo ('mouth of the Ts'amakko'), or simply Ts'amakko. It is a Cushitic language, spoken in Southwest Ethiopia and belongs to the Dullay cluster of Lowland East Cushitic. The number of speakers is about 10,000. The data…

Can drugs that target host signaling pathways be used to eradicate antibiotic-resistant bacteria?

How many species of plants, animals and fungi live in urban nature? in 2026 are Leiden, Leiderdorp, Oegstgeest and Katwijk observing and recording how many unique species there are, to put the state of urban nature on the map. Together everyone from May 1st till 30th of June will record every spider,…

This ecological community has long been known to affect host biology, and their diverse roles have been further clarified in recent years following numerous studies of animal:microbiota interactions in diverse systems.

Provenance and distribution of raw materials

In November, Somalia was the latest country to join the East African Community (EAC). This follows the Democratic Republic of Congo's accession to the regional intergovernmental organisation in March.

In the Netherlands, as elsewhere in the world, many patients who are in a palliative care trajectory prefer not to receive full or explicit medical information. This is more often the case for patients with ethnic or cultural minority backgrounds. As open-information provision is the norm, non-disclosure…

Promotor: A.W. van der Vaart

How does the Chinese government communicate with its citizens? Yuxi Nie obtained her PhD with her thesis on communication strategies of the Chinese state media agency Xinhua. She discovered that on social media, Xinhua communicated in different ways, depending on the target group.

Anthropogenic change is reshaping ecological systems, raising concerns about increasing transmission of infectious diseases. Among these, mosquito-borne diseases may be particularly sensitive to environmental change, as their transmission depends on vector populations.

This thesis describes the antimicrobial discovery strategy developed in our group, the den Hertog Group at the Hubrecht Institute. It includes a cultivation-based screening approach for novel antimicrobial agents from the source of fungi, and a bacterial time-lapse imaging approach for antimicrobial…

Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver

In this latest contribution to mimetic studies, Nidesh Lawtoo joins forces with leading international theorists of the posthuman to broaden the reach of the mimetic turn beyond human imitation.

Cities need to become greener, more biodiverse, and climate-resilient. However, many organisms that are vital for the functioning of urban green spaces and the wellbeing of urban citizens remain largely unknown.

Report on the Excavations of the National Museum of Antiquities Leiden in the Balikh Valley, Syria.

The Laboratory for Archaeozoological Studies is an advanced laboratory with advanced Leica stereomicroscopes and measuring instruments and an extensive reference collection which is used for research e.g. the identification of fossil remains. The collection is also used for teaching students the anatomy…

This thesis has described novel synthetic methods to produce a variety of (glyco)peptides and their application in the study of various immunological processes.

Developing a new way to measure marine biodiversity at high resolution, by listening to it.

The handbook is a wide-ranging survey of a crucial period in prehistory during which many social, economic, and technological changes took place. Written by specialists in the field, the book provides coverage both of the themes that characterise the period, and of the specific developments that took…

This project aims to study the Aesopian fable from 1500 to the present day in its complex relationship between text, illustration and education, adopting a broad, transnational perspective.

The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments.

Investigating the relations between Tupi Indigenous Knowledge, Museum Collections and the Dutch Colonization of Brazil

The aim of this research area is to be able to predict human drug response on the basis of mathematical models that are developed using preclinical experiments and prior knowledge.

In this thesis, two potential therapeutic targets for diabetic nephropathy were dentified and investigated. First, we show that glomerular clusterin is upregulated in diabetic nephropathy and demonstrated that recombinant clusterin protein can protect the podocytes against oxidative stress in vitro.…

Human vocal communication and music perception represent advanced cognitive skills, seemingly innate and universal. These faculties encompass a range of perceptual and cognitive abilities. Cross-species research sheds light on the origins of musicality by investigating whether these traits are shared…

One of the major limitations in culturing complex tissues or organs is the lack of vascularization in the cultured tissue. Development of a functional capillary bed could overcome this problem.

High-throughput holistic preclinical screens are increasingly used in drug discovery, to assess both drug efficacy and drug safety.

Investigating the making of knowledge in anthropology and natural history in colonial and postcolonial Indonesia.

In this thesis, I investigated the neurogenetic properties of Neotropical bat species. Bats represent the second largest mammalian order (Chiroptera) in the world, with Neotropical bats constituting about 13% of the total number of bat species.

The subject areas covered encompass functional genomics, signal transduction, cellular differentiation, development, host-microbe interactions and animal behaviour.

From Complex Hunter-Gatherers to Early Urban Societies

Karmaşık Avcı-Toplayıcılardan Erken Kentsel Toplumlara

Eight university vegetable patches will soon join the display at the Hortus botanicus. The sun shone down on almost 40 enthusiastic students and staff as they started work on the new Community Garden there earlier this month.

The Leiden University Network for Health in Africa (LUNHA) aims to shift the focus of global health to be more about justice, fairness, and inclusion.

On November 25, Dr Araceli Rojas presented her book El tiempo y la sabiduría: un calendario sagrado entre los ayöök de Oaxaca. The event took place in the Central Public Library of the State of Oaxaca, in the heart of Oaxaca City, at 7 pm.

Last week, our The Hague Diplomacy Platform was awarded a 10.000 euro grant from the KNAW's 'Valued'-fund to help us in our efforts in science communication and spreading knowledge about diplomacy to a wider public.

On May 15th, from 15.15 to 17.00 in the Vossiusroom, Leiden University Libraries will host a program on web-archiving and digital archives of Chinese communities in the Netherlands and Indonesia.