RARE-NL, a new collaboration between university hospitals, hopes to find treatments for rare diseases. Professor Teun van Gelder is representing the LUMC in the initiative.

On the 19th of May 2020, our dear colleague and friend Professor Dr. Huib Ovaa has passed away from prostate cancer. Last summer Huib became ill, and in first instance it appeared that he had attracted a relatively harmless infectious disease. Unfortunately, it became soon apparent that he suffered…

The making of sacrifices seems part and parcel of any elite sportsperson’s life. Remarkably, the insights that we find in the current literature in social sport studies are not able to make sense of the references to sacrifice in the data that emerged in the context of this study on the social significance…

In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.

The League of European Research Universities (LERU) is a group of 24 leading European research universities.

Leiden University has made history with its many scientific discoveries; a history that is also illustrated in a variety of books and films.

Promotor: B. vd Water, T. Schmidt, Co-Promotor: E.H.J. Danen

The Cardiovascular Pharmacology research group headed by Ilze Bot aims to elucidate the mechanisms that underlie atherosclerotic plaque destabilization, which is the key process that leads to acute cardiovascular syndromes such as a myocardial infarction or stroke.

Key publications of the Cancer Drug Target Discovery group

LUCITH runs a number of initiatives and programmes. Below you will find a list of initiatives and activities by the Centre for Islamic Thought and History.

While bioinformatics methods deal with the analysis of sequence information (be it proteins or DNA), the field of cheminformatics is concerned with the analysis of small-molecule datasets.

Antimicrobial resistance (AMR) is the phenomenon that pathogens become insensitive to the antibiotics that we use against them. A growing number of pathogens is becoming resistant, with methicillin-resistant S. aureus (MRSA) as the most famous example. But while the threat of AMR represents a slow-moving…

Operators in the Lexicon opens with an old chestnut: why are there no natural single word lexicalizations for negations of the propositional operator and and the predicate calculus operator all: why neither *nand nor *nall?

Source: J Cheminform, Volume 6, Issue 1 (2014)

The Leiden Institute of Chemistry (LIC) is the basis for research and collaborations of the Leiden chemistry groups. Chemistry is the central science enabling a healthy future in a sustainable society. Chemistry researchers at Leiden University take a fundamental approach in finding tailored solutions…

In this research I assess the impact of the recently discovered gas reserves south off Cyprus on the escalation of the Cyprus conflict.

Research groups in the Biological & Soft Matter Programme unravel mechanisms in biological processes and develop novel bio-inspired soft materials.

Discovery and development of Central Nervous System (CNS) drugs is hampered by high attrition rates.

Imagined Voices deals with a form of composition, music with on-screen text, in which the dynamic between sound, words and visuals is explored.

The main focus of the thesis is the discovery and development of novel inhibitors of bacterial metallo-β-lactamases (MBLs).

Enabling volume-restricted metabolomics using next-generation microscale analytical tools.

This book aims to unravel some of the mysteries surrounding this exceptional group of larger-than-life Bronze Age blades.

For three millennia, carved sculptures were ubiquitous among ancient peoples in the Americas. Sculpted in stone, metal or wood, they developed into the well-known totem poles, colossal Olmec heads, royal Maya stelae and golden Inca statues.

The present thesis focuses on the pharmacological concept of drug-target interaction, which dates back to the beginning of modern pharmacology.

The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.

Do you live in Egypt and have you always wondered about all the pharaonic heritage surrounding you? This spring NVIC organizes a beginner’s level, introductory course in Egyptology. In 6 richly illustrated lessons, the history of ancient Egypt will be brought to life, both chronologically as well as…

Designing and synthesizing high-affinity ligands for a given drug target have always been among the more important challenges in the drug discovery process.

Conference

Get to know us through our online and in-person events for prospective students!

Arts and leisure, Arts and leisure

Many students receive their first job offer during or right after their Business Studies internship. After graduating you can also aim for a career in Bio-Pharmaceutical research.

Soil bacteria can produce a wealth of antibiotics that are new to us, claims Gilles van Wezel, Professor of Molecular Biotechnology at the Institute of Biology Leiden. His research group has developed a method that can rapidly identify and produce these unknown compounds.

Great news! From Whit Monday at noon, the oldest botanical garden in the Netherlands will be open for visitors again. After twelve weeks of closure, visitors will be able to come and enjoy everything that grows and blossoms in the heart of Leiden's city center. In order to offer all visitors and staff…

Australian cell biologist Melissa Little and Dutch physicist Robbert Dijkgraaf will each be awarded an Honorary doctorate at the Dies Natalis of Leiden University in February 2019. They are receiving these awards for their services to science.

On Wednesday the 23rd of March 2016, Prof. Richard Leakey, the world renowned palaeoanthropologist and conservationist from Kenya and Honorary Member of the LEAD Programme, visited the LEAD Office to contribute to a PhD Workshop.

The Hortus Botanicus is celebrating its 425-year anniversary this year. It’s the oldest botanical garden in the Netherlands, but how did it come into existence and what kind of research takes place there?

A team of astronomers led by Dutch scientists have directly imaged a giant planet orbiting at a large distance around a sun-like star. Why this planet is so massive, and how it got to be there, is still a mystery. The researchers will publish their findings in the journal Astronomy & Astrophysics.

Researchers from Japan and the Netherlands who were previously involved in the discovery of an exoplanet with huge rings have now calculated that the giant rings may persist more than 100,000 years, as long as the rings orbit in the opposite direction to that of the planet around the star. Their findings…

PhD candidate Marc Baggelaar of the Leiden Institute of Chemistry (LIC) graduated cum laude on Thursday 6 April. His thesis on the endocannabinoid system in the brain is very comprehensive and of high quality, according to the jury. ‘A very talented young scientist, that definitely belongs to the top…

Astronomers led by Leiden astronomer Sebastiaan Haffert have directly imaged two planets that are gravitationally carving out a wide gap within a planet-forming disk surrounding a young star. While over a dozen exoplanets have been directly imaged, this is only the second multi-planet system to be p…

On Friday 17 April Leiden Mayor Henri Lenferink will officially open the new Metabolomics Facility of Leiden University. The facility’s ultimate goal is to prevent disease and to improve health throughout the human lifespan.

Welcome to the WIIS NL community! We are excited to be launching our newsletter in the week we celebrate International Women's Day.

Leiden archaeologists have identified a number of bone fragments that were excavated in Germany two years ago. The fragments are from a sabre-toothed cat and appear to be parts of the skull of a prehistoric feline that is over 300,000 years old.