These are two separate Erasmus+ International Credit Mobility projects with Monash University in Australia, one of Leiden University’s Faculty of Law, the other of the Leiden Academic Centre for Drug Research (LACDR).

The cannabinoid receptor type 2 (CB2R) is associated with several inflammatory diseases with an unmet medical need (e.g. Alzheimers, multiple sclerosis, reumatoid arthritis). Development of new chemical biology strategies to study this protein is essential to aid future development of drugs for these…

Source: International Journal of Cosmetic Science, Volume 37, Number 1, pp. 158-158 (2015) ISBN: 0142-5463

uman skin equivalents (HSEs) are in vitro 3D-skin models that mimic many aspects of the native human skin (NHS) and can be a valuable tool.

The loss of T-cell homeostasis and tolerance towards self-antigens is the underlying cause of autoimmune and inflammatory diseases like atherosclerosis, rheumatoid arthritis or type I diabetes. Traditionally, the treatment of these diseases consisted on systemic immune suppression, which can entail…

Source: International Journal of Cosmetic Science, Volume 37, Number 1, pp. 148-148 (2015) ISBN: 0142-5463

This project is funded by the Dutch Cancer Society. The project will be part of an ongoing research line aimed at identifying mechanisms of cancer therapy resistance and metastasis. In this project, it will be investigated how the Grainyhead family of transcription factors controls therapy response…

This thesis describes our search to identify and understand possible regulatory mechanisms of integrin α6β4 in cell-matrix adhesion and intracelular signaling.

A special find has been made in the Alkmaar Regional Archive: a number of 17th-century book bindings contained pieces of parchment from a manuscript from the 11th century. The original manuscript may have belonged to a princess who fled England after the Norman Conquest.

Every year, more than three thousand businesses are declared insolvent in the Netherlands. The purpose of bankruptcy is to divide the assets of these companies among the creditors. However, the value of the claims of the creditors often exceed the value of the assets of the company

What kinds of vocal music were not typically transmitted in written musical notation? Can specific ‘lost’ song forms - siciliane, giustiniane, le Grechesche, gli stili “regionali“ nel canto del quattrocento - be more precisely identified than they have been until now, both in musicological research…

Early Medieval Grave Reopenings in the Low Countries

Today’s performances of medieval polyphony have a lot in common with those of other ‘classical’ or ‘early’ music. Ensembles perform pieces written by known or lesser known composers, which the listener can revisit by listening to recordings or reading a score.

This book rovides an economic history of Portugal over the course of eight centuries, from 1143 through to 2010 and situates Portugal's economic growth within the context of European development. It also responds to fundamental questions about when, how and why the economy expanded, stagnated or co…

The department of World Archaeology combines research and education about regions all over the world, from Human Origins to the Middle Ages, and from Europe, to Asia, Africa and the America’s. That broad range in time and space makes the department a dynamic pluriform community with many different approaches,…

The Department of Archaeological Sciences seeks to achieve the highest standards of excellence in science-driven education and archaeological research across the globe and across all periods.

Bioarchaeology covers the study of all biological remains from archaeological sites.

Do you have questions or remarks? Please contact the coordinators of the Medieval and Early Modern Studies cluster.

This dissertation addresses the different use of the same philosophical model: immanent teleology. In this work Aristotle, the founder of the study of final causes, is put in relation with the modern French evolutionary thinker Henri Bergson, the philosopher of time. The dissertation tackles the two…

We are aiming to develop novel technologies to allow better sample preparation or coupling of analytical methods to (i) analyse ultra small samples, (ii) to analyse more metabolites in a quantitative manner and/or (iii) increase the sample throughput.

The aim of this thesis was to develop aluminium salt-based nanoparticles that may ultimately be used as adjuvant in human vaccines.

Visualising structures of life

Tuberculosis (TB) is associated with 1.5 million deaths annually. There is a need exists to optimize both current as well as novel antibiotic combination treatment strategies to improve the effectiveness and safety of treatments against TB.

This thesis focuses on the development of sample-preparation methods for small amounts of samples and applying the developed methods to muscle tissues to investigate the mechanisms involved in sarcopenia.

The Advisory Board consists of five eminent scientists with specialist expertise in complementary disciplines. They all have prominent positions in the field of Computer Science in the Netherlands outside our own institute.

To improve treatment of breast cancer patients it is important to understand all stages of breast cancer from initiation to in situ disease and progression to invasive disease. In this thesis we use intraductal injections of patient derived tissue to model ductal carcinoma in situ and invasive breast…

Members of our research team give different types of presentations and lectures.

FAIR-ASSESS is supported by a scientific committee comprising internal members connected to Leiden University and external members from outside the university with expertise in the field.

Live presentation Farmacie at the Master's Online Open Days, 5 October 2023

Op 25 maart organiseert het Utrecht Centre for Medieval Studies een online lezing door Angus Stewart, getiteld “The Mongol Invasions of Syria and the Armenians: Changing Perspectives”.

Lecture, Book launch event

Bones hold a wealth of information about a person’s life, revealing details about where they came from, how old they were when they died and what diseases they may have had. Scientists can use this data to piece together aspects of an individual's life, offering valuable insights that can help address…

An Investigation into the role of copper-alloy craft production in the early medieval economy of northwest Europe.

Do you have questions or remarks? Please contact the core team of the Centre for Islamic Thought and History.

Nowadays they can cause the fall of ministers, but once upon a time receipts were a new phenomenon. Associate Professor Robert Stein is to receive a grant from NIAS to map their origins.

The Learning and Behavior Problems in Education program group is responsible for teaching in the area of learning problems.

Arts and leisure, Arts and leisure

Supervisor: Anna Vlachodimou

The research conducted at the Leiden Academic Centre for Drug Research is clustered within the divisions of BioTherapeutics, Cell Systems and Drug Safety, Medicinal Chemistry and Systems Pharmacology and Pharmacy, and the Metabolomics and Analytics Centre.

Research in this group, headed by Gerard van Westen, focusses on computational methods integrated in different parts of the drug discovery process. More specifically, topics include innovative treatments for cancer, selectivity modeling, translational research, allosteric modulation, drug resistance…

In the Research in Bio-Pharmaceutical Sciences specialisation you will perform research on various topics in the area of Drug Discovery and Development. The programme offers a high level of flexibility and can be tailored to your scientific interests. The major research project is hosted by the Leiden…

In this project, we aim to obtain a quantitative understanding of the role of the immune system in tumor regression, of the role of tumor cell heterogeneity in cancer growth and of tumor cell migration properties.

LUMC Technology Focus Area (TFA) Data Analytics is een samenwerkingsverband van verschillende onderzoeksgroepen in het LUMC die nieuwe kwantitatieve en computationele methodologie ontwikkelen voor biomedisch en klinisch onderzoek.

Tot voor kort was de kartering van oppervlaktevondsten de geijkte manier om het in de bronstijd bewoonde gebied in West-Friesland in kaart te brengen. In dit rapport gebaseerd op archeologisch onderzoek in 2012-2015 wordt uiteengezet wat de relatie tussen de oppervlaktevondsten en de aan- en afwezigheid…

Two researchers at the Faculty of Archaeology have received a Veni award from the Netherlands Organisation for Academic Research (NWO). This award offers promising young researchers the opportunity to further develop their ideas for a period of three years.

What can we learn from how maritime conflicts were managed in the past? What significance did Maritime Conflict Management have in shaping the standards of diplomacy and international law in pre-modern Atlantic Europe (1200-1600)?

Overview of granting opportunities in the wider digital humanities community. Follow links for the most up-to-date details on deadline dates/times and conditions for applying.