Polymyxins are clinically used antibiotics, discovered in mid-20th century. Once abandoned due to excessive nephrotoxicity, they are now used increasingly to address infections caused by multi-drug resistant Gram-negative bacteria.In this thesis, we describe the development and synthesis of analogues…

In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.

In this book, a new generation of scholars offers fresh perspectives on the history of the Dutch slave trade. Traditionally, Dutch research has focused on business practices, often overlooking the enslaved and the complexities of illegal trade and violence.

This book brings together a collection of emergent research that moves the debate on desistance beyond a general consideration of individual and social structural influences.

In this study, Bibi van den Berg and Sanneke Kuipers from ISGA, explore the ways in which cyber-related incidents may lead to crises

Currently the focus of the project is the development of a tool that utilizes dimensionality reduction techniques in order to analyze and interpret the lexical and phonological variation between different sign languages. Additionally, the application of deep learning techniques for the extraction of…

Human and animal cells are very complex: very different chemical processes are going on at the same time, but they are separated from each other because the cells are divided in compartments. These compartments may also have a profound effect on the potential efficacy of therapeutics, because the drug…

Following the terrorist attacks in Paris (November 2015) and Brussels (March 2016), Belgium’s counterterrorism policy has been heavily criticized – domestically and worldwide.

Until the 1990s, the only known planets were those in our Solar System. Three decades later, several thousand exoplanets have been discovered orbiting stars other than the Sun, and substantial efforts have been made to explore these strange new worlds through spectroscopic analyses of their atmosphe…

Promotor: J.P. Abrahams, Co-promotor: T. Grüne

Advanced mass spectrometry of glycosphingolipids takes the central stage in this thesis. Investigations focus on characterization of glycosphingolipid metabolism in health and disease with emphasis to the detection and accurate quantitation of known and so far unknown glycosphingolipids and closely…

The book offers different theoretical perspectives to help examine the process of public sector reform. In addition it gives an overview of the major trends in the core areas of the functioning of the public sector.

Thirty years ago, mutations in the BRCA1 gene were first linked to hereditary breast and ovarian cancer, establishing a genetic basis for cancer development.

Panel discussion

Lecture, Research Seminar

The LUGO Press is a student publication forum, rooted in academia and journalistic practices and published by the Leiden University Green Office.

In what ways does Atelier education contribute to skills development, active learning, interactions between students and staff, and connections between disciplines of law?

Assessing the feasibility and legitimacy of the current model of global tax governance and the role of the OECD and EU in international tax law-making.

What with coronavirus, the American elections and the Brexit botheration, we had almost forgotten that something miraculous happened in 2020: the repressed people of Belarus rallied against dictator Alexander Lukashenko, who has been in power for 26 years. Months later, what remains of the protest?…

After four successful editions, the Academy for the Rule of Law (Dutch) course, a collaboration between Leiden University and the Montesquieu Institute, has evolved into its final form.

In October 2014, Leiden University established the ‘Leiden University Teachers’ Academy’. Helen Westgeest, who lectures in the BA and MA Art History and MA Media Studies, was put forward by the Faculty of Humanities for appointment in the so-called ‘LTA’.

Conference, Meet us in your country

Conference, Meet us in your country

Conference, Meet us in your country

Conference, Meet us in your country

Conference, Meet us in your country

Conference, Meet us in your country

Leiden artist Jos Agasi gets to create the artwork for the atrium of the new Gorlaeus Building. His work was chosen from several entries and will be a real eye-catcher in the building. The artist has a fascination for light and uses it to create works of art with all kinds of materials, objects and…

Aukje Beers combined theory and practice, as well as chemistry, biology, and computer models. In this way, she discovered two protein inhibitors during her master’s project that could contribute to the development of a new cancer drug. For her research, Beers received the Unilever Research Prize on…

The Roosevelt Chair in New Diplomatic History is sponsored by the Roosevelt Institute for American Studies (RIAS) in Middelburg, and the new position further strengthens the connection between the RIAS and Leiden.

The dissociative chemisorption of methane on metal surfaces is of fundamental and practical interest, being a rate-limiting step in the steam reforming process. The reaction is best modeled with quantum dynamics calculations, but these are currently not guaranteed to produce accurate results because…

Leiden University Centre for Digital Humanities (LUCDH) has had a new director since 1 February. Associate Professor Angus Mol wants to connect people and knowledge in his new role.

What does life look like after International Studies? For Chris Colijn who graduated in 2018, it involves working on his master’s in Russian and Eurasian Studies, in combination with a bustling traineeship for “Raam of Rusland”, a think tank, focusing on Russian and Ukrainian politics, economy and culture.…

Mathematician Robbin Bastiaansen, physicist Irene Battisti, pharmacist Fouzia Lghoul-Oulad Saïd and physics and astronomy student Maite Boden are the winners of the annual prizes of the Faculty of Science. Boden was honoured as the first Young Star, a new prize for the best bachelor’s student of the…

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Mums posting photos and videos of their child on Instagram and TikTok and also earning loads of money doing so. Kidfluencers, momvloggers and familyvlogs are very popular, in the Netherlands too. But the lack of legislation regulating these activities means that these children are barely protected.…

While offshore wind farms generate clean and green energy, scientists are becoming increasingly aware of the harmful impact they may have on marine life. To get a better overview of these impacts and to find the best locations for future wind farms, environmental scientist Yali Si and her colleagues…

How can you learn about women’s history if they are under-represented in historical sources? Look at news coverage of crime, says Clare Wilkinson, PhD candidate in gender and history. ‘Historical crime reporting offers a glimpse into forgotten groups.’ The doctoral defence will take place on 23 Apri…

Hanneke Hulst has held the new Leiden chair in Neuropsychology in Health and Disease since 1 September. From 1 January she will also be chair of the Health, Medical and Neuropsychology (HMN) unit. ‘HMN is my new base. I’m curious to find out about the people who work here, what they do and what motivates…

What impact does ethnic profiling and accusations of ethnic profiling have on organizations and the border police officers working at the operational level, and what structural factors on the societal and organizational level contribute to the process of ethnic profiling? Over a period of three years…

In the controlled, censored, and taboo-ridden media landscape of communist China, one would not expect seeing a television show featuring real people having actual conflicts. Yet reality programmes about conflict mediation are mushrooming in the People’s Republic. Both the public and the authorities…

Orange the World 2025