How did local lifeways and crafting practices persist and develop in the diverse environments of the increasingly interconnected Gulf of Fonseca (AD 400-1521)?

Tracing the residues of Neolithic activities through the study of stone artefacts

Which basic characteristics and skills and knowledge influence the use of and actions based on real-time student data presented on a teacher dashboard in primary education?

Alexander Kros studies supramolecular systems in a biological environment. The unifying theme between the projects in my lab is specific molecular recognition, i.e. the intermolecular interaction between complementary molecules with high affinity and selectivity. Studying, imitating and dissecting processes…

Prof. Dr. Joost N. Kok is panel chair in the research assessment of Tampere University of Technology (TUT), Tampere, Finland.

As far back as 1575, Leiden University researchers have been leaving their mark on the world.

The healthcare system still treats children as though they are small adults. And that approach does not work, says Lissy de Ridder, professor and head of Paediatrics, in her inaugural lecture.

The work done by SUMO proteins in the cells of our body is of vital importance. Molecular cell biologist Alfred Vertegaal has been studying these proteins for nine years, first with a Veni subsidy and then with a prestigious Vidi subsidy.

Researchers at Leiden University have demonstrated that tumours can apply mechanical means to attract the blood vessels they need to be able to grow. The team published this discovery on 2 March in Nature Scientific Reports.

Treatment and care for cancer patients is becoming increasingly advanced. For example, surgeons can now perform operations with much greater precision, and therapeutic vaccines are being developed to prompt the patient’s immune system to fight cancer. Work is also being done on better early diagnostics,…

The Chemical Probe Facility is part of the Leiden Early Drug Discovery & Development (LED3) center. Activity-based protein profiling (ABPP) is one of the pillars of chemical biology. ABPP determines the activity of entire protein families in living cells and tissues under physiological conditions, such…

The goal of hit and lead optimization is to optimize suitable chemical starting points that can modulate a drug target. The methods and technologies used are similar to those in Hit Discovery, but once the compound has shown activity in an animal model, it moves from 'hit' to 'lead.'

Core Facilities are shared resources that provide access to instruments, technologies and services to researchers across the Institute of Biology.

The Minor in Teaching was introduced in 2009 as a new initiative to introduce and prepare bachelor students for teaching. Student numbers are low, however, especially of mathematics and science students.

Leiden University has awarded its prestigious University Medal to Emeritus Professor Lex van der Eb. As a pioneer in genetics and molecular biology, he received this honour for his services to science and his key role in the development of the Leiden Bio Science Park (LBSP).

The Wadi al Jizzi Archaeological Project is a systematic and long term archaeological surface survey project, investigating the rich archaeological heritage of the Wadi al Jizzi region (Oman) from the Paleolithic until the early Modern period.

The Lowlands pop festival is inviting scientists to make proposals for research at this year's festival (19 to 21 August).

How do lipases in Mycobacterium tuberculosis help the bacteria survive, and can we target them to create new antibiotics?

Some people are predisposed to develop cancer. Mutations in genetic material that increase a person’s chances of developing cancer can already be present at birth. Researchers are closely examining these mutations to learn more about how cancer begins to develop.

The CMCB comprises research groups from the Institute of Biology Leiden (IBL), the Leiden Institute of Chemistry (LIC) and the Leiden University Medical Center (LUMC).

The discovery of new medicines is a tedious and lengthy process. On average, over 10,000 molecules need to be studied for one to become a drug and reach the patient. Part of that process are the very costly clinical trials in humans, and candidate drugs often fail due to side effects or lack of efficacy.…

NL-BioImaging AM is a distributed research infrastructure aimed at promoting progress in the most cutting edge microscopy technologies and providing open access to these technologies to a broad community of academic and industrial users. All Netherlands bio(medical) microscopy centers participate.

Can the conditioning paradigm be used for checkpoint inhibition cancer treatment?

By carrying out fundamental research and providing excellent education, universities become a breeding ground for innovation and entrepreneurship.

What are the host immune defence mechanisms that control intracellular infections and how are these subverted by pathogens?

How does speculative literature respond to or incorporate the aural, sonic, or noisy? How are sonic technologies co-opted into practices of worldbuilding? How does the speculative mode of artistic and literary enquiry generate new possibilities of listening?

Research at the MCBIM group is comprised of the following research themes:

In this research group, headed by Laura Heitman, novel receptor concepts in drug discovery are studied, aiming to increase the effectivity of medicines. Many drugs act via so-called G protein-coupled receptors (GPCRs) and therefore our research is mainly focused on understanding and improving drug-receptor…

We have recently discovered that there are biological proteins that phase separate out of solution much the way oil will de-mix from water (see movie). These form dense, liquid-like phases called protein condensates.

Artificial photosynthesis aims to produce fuels from solar energy using chemical processes. In semi-artificial photosynthesis, a hybrid approach is taken using both chemical and biotechnology components. We are developing hybrid systems, coupling light-harvesting nanoparticles to redox-enzymes (oxidoreductases)…

Our research in the area of safety sciences aims to increase the mechanistic understanding of cellular toxicity of drugs and, in a broader sense, chemicals.

Despite substantial progress in understanding tuberculosis (TB), the eradication of the TB epidemic is still far from reach.

Making an impact by creating solutions for the challenges of the future. That’s what we do through our education and research in biodiversity and sustainability, artificial intelligence, complex networks, new medicines, quantum technology, and galaxies.

The Leiden Institute of Chemistry (LIC) is the basis for research and collaborations of the Leiden chemistry groups. Chemistry is the central science enabling a healthy future in a sustainable society. Chemistry researchers at Leiden University take a fundamental approach in finding tailored solutions…

New and reemerging infectious diseases call for innovative and efficient control strategies of which fast vaccine design and development represent an important element.

On 2 May, Sophie Starrenburg defended the thesis 'Striking a balance between local and global interests: communities and cultural heritage protection in public international law'. The doctoral research was supervised by Nico Schrijver and Yvonne Donders.

This book explores the relationship between the production of new urban spaces and illiberal community-making in contemporary India. It is based on an ethnographic study in Noida, a city at the eastern fringe of the state of Uttar Pradesh, bordering national capital Delhi.

This thesis investigates the grammar of Sheko, an Omotic language spoken in southwest Ethiopia.

On May 2nd, Petr Kocharov succesfully defended his doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Petr on this great result.

This is the first full-scale reference grammar of Classical Greek in English in a century.

Representing Japanese Colonial 'Heritage' in Taiwan

This is a study of Plateau Shimakonde, a sub-dialect of the Makonde language which is spoken on the Makonde Plateau in northern Mozambique.

On May 3rd, Varun de Castro Arrazola succesfully defended his doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Varun on this great result.

Biological cells, the basic building blocks of all life forms, are surrounded by a lipid membrane. More than half of the membrane is occupied by membrane proteins, which can regulate the cell functionality through specific arrangements.

On Tuesday 14 January 2025 Milan Ismangil successfully defended a doctoral thesis and graduated.

The ongoing increase in antimicrobial resistance combined with the low discovery of novel antibiotics is a serious threat to our health care.

Barbarism: from the 18th century to the present.

The general objective of this thesis is to determine a typology of verbal derivation in Ethiopian Afro-asiatic languages.