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2,314 search results for “protoplanetary drug” in the Public website

• Translational Immuno-Pharmacology

  The Translational Immuno-Pharmacology group works on translating the efficacy of anti-infective therapy from preclinical (e.g. in vivo) to clinical, and is led by Rob van Wijk. Infectious diseases, such as tuberculosis, are in constant need of new therapies that work better, faster, and with less risk…

• Optogenetic activation of intracellular adenosine A2A receptor signaling in the hippocampus is sufficient to trigger CREB phosphorylation and Research output

  Source: Mol Psychiatry (2015)

• Cationic liposomes loaded with a synthetic long Peptide and poly(i:C): a defined adjuvanted vaccine for induction of antigen-specific T cell Research output

  For effective cancer immunotherapy by vaccination, co-delivery of tumour antigens and adjuvants to dendritic cells and subsequent activation of antigen-specific cytotoxic T cells (CTLs) is crucial. In this study, a synthetic long peptide (SLP) harbouring the model CTL epitope SIINFEKL was encapsulated…

• Finding and valorizing new antibiotics using AI Leiden Early Drug Discovery & Development

  Antibiotics are a class of medicine most people take for granted. But pathogenic bacteria are becoming more and more resistant to our antibiotics, and this poses a great challenge for future treatments. There is thus a great societal need to identify new molecules that can address new targets and be…

• Microscale Analytical Tools Metabolomics and Analytics Centre

  Enabling volume-restricted metabolomics using next-generation microscale analytical tools.

• Exploring the potentials of nurture: 2(nd) and 3(rd) generation explant human skin equivalents Research output

  BACKGROUND: Explant human skin equivalents (Ex-HSEs) can be generated by placing a 4mm skin biopsy onto a dermal equivalent. The keratinocytes migrate from the biopsy onto the dermal equivalent, differentiate and form the epidermis of 1(st) generation Ex-HSEs. This is especially suitable for the expansion…

• Lipid to protein ratio plays an important role in the skin barrier function of atopic eczema patients Research output

  OBJECTIVES: To determine whether the lipid/protein ratio and the total dry SC mass per surface area are related with the skin barrier function of controls and AE patients.

• The 6th Virtual ChemBioTalks 2026 Event - 29 September 2026

  Conference

• When structure-affinity relationships meet structure-kinetics relationships: 3-((Inden-1-yl)amino)-1-isopropyl-cyclopentane-1-carboxamides as Research output

  Source: Eur J Med Chem (2015)

• Regenerative medicine

  Repairing organs, tissues and cells to fight chronic diseases.

• Boosting the host immune system to fight tuberculosis Research output

  New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.

• Explant cultures of atopic dermatitis biopsies maintain their epidermal characteristics in vitro Research output

  Atopic dermatitis (AD) is a common inflammatory skin disorder characterised by various epidermal alterations. Filaggrin (FLG) mutations are a major predisposing factor for AD and much research has been focused on the FLG protein.

• Affinity Cell Systems and Drug Safety

  Designing and synthesizing high-affinity ligands for a given drug target have always been among the more important challenges in the drug discovery process.

• Microglial lipid metabolism: a delicate balance Research output

  Microglia support the central and peripheral nervous system by forming the first line of defense against hazardous events. Microglia are increasingly acknowledged as critical players in neurodegenerative diseases, highlighting them as potential therapeutic targets.

• Bioactive Molecules in Plant Sciences Plant Sciences

  Plant Sciences' contribution to the Bioactive Molecules research theme is to identify new plant bioactive molecules, and unravel their mechanisms of action in plant development or health, and the regulatory networks and (bio)synthetic pathways required for their production.

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  Xuesong Wang Senior technician

  Faculty of Science

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  Jurjun van der Velde PhD candidate / Guest

  Faculty of Science

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  Nanette Vrijenhoek PhD candidate

  Faculty of Science

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  Annaloes Fokkelman-Klip Research Analyst

  Faculty of Science

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  Kirsten Veltman Postdoc

  Faculty of Science

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  Bart Lenselink Guest Scientist

  Faculty of Science

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  Xiaobing Zhang PhD candidate

  Faculty of Science

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  Ine Tijdens Health, safety and environment coordinator

  Faculty of Science

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  Chantal Pont Lab Manager

  Faculty of Science

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  Lukas Wijaya Postdoc

  Faculty of Science

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  Johannes Schimming PhD candidate

  Faculty of Science

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  Sabine de Winter PhD Candidate

  Faculty of Science

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  Linglu Xu PhD candidate (contract)

  Faculty of Science

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  Klara Beslmüller PhD candidate / Guest

  Faculty of Science

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  Elpida Lymperi PhD candidate

  Faculty of Science

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  Britt Duijndam PhD candidate

  Faculty of Science

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  Kirsten Snijders PhD candidate

  Faculty of Science

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  Sibel Bahtiri PhD candidate

  Faculty of Science

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  Lucy Sinke Postdoc

  Faculty of Science

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  Mick van Schaick PhD candidate

  Faculty of Science

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  Gerard Mulder Professor emeritus

  Faculty of Science

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  James Stevens Postdoc / guest

  Faculty of Science

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  Arnoud Sonnenberg Professor emeritus

  Faculty of Science

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  Roshni Nair PhD Candidate

  Faculty of Science

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  Fengjiao Zhang PhD candidate-guest

  Faculty of Science

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  Steven Kunnen Postdoc

  Faculty of Science

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  Marina Gorostiola González PhD candidate

  Faculty of Science

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  Natasha Tahir PhD candidate

  Faculty of Science

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  Michiel van Dijk PhD candidate

  Faculty of Science

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  Vera van der Noord Postdoc

  Faculty of Science

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  Tamara Danilyuk PhD candidate

  Faculty of Science

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  Hanneke Leegwater Guest

  Faculty of Science

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  Linda van den Berk Guest PhD candidate

  Faculty of Science

• Internship Discovering and developing drugs

• Infrastructure Systems Pharmacology and Pharmacy

  An overview of our infrastructure at the SPP division: