How do people living in a remote part of Northern Mongolia experience the post-socialist transition that occurred twenty years ago? Based on extensive fieldwork, cultural anthropologist Richard Fraser argues that this is not at all clear. In his PhD dissertation, he developed a new framework based on…

Understandably, coronavirus is often viewed from a medical perspective. However, researchers in the social sciences and humanities possess a great deal of expertise that could improve our understanding of the virus outbreak and its impact on society. A new portal is consolidating this knowledge.

Vietnam’s record of expanding access to education, and especially its performance on international assessments such as PISA, has raised questions about what Vietnam got right, how, and why and what insights Vietnam’s experiences might offer for efforts at improving the performance of education systems…

Slavoj Žižek is one of the most prominent public intellectuals of the left. His central claim holds that “today, it is more crucial than ever to continue to question the very foundations of capitalism as a global system”.

There are many complex links in the chain that provides patients with new drugs: from fundamental science, to clinical tests, to production. The entire chain can be found in Leiden. Leiden University, the Leiden University Medical Center (LUMC) and the businesses at the Leiden Bio Science Park (LBSP)…

PhD defence

This book reconstructs the life of Lie Alma, a Dutch teacher and antifascist activist, and her role in international women’s peace politics and the struggle against fascism, poverty and social inequality.

Archaeologist Prof Bleda Düring has been awarded a prestigious ERC Advanced Grant for his research on the emergence of social inequalities in the transition from the Copper Age to the Bronze Age in Cyprus. Using excavations, isotope analysis and cultural interpretations, he investigates how and why…

An overview of awards and prizes granted to our staff and students in 2017, as well as special appointments and royal distinctions.

If you are interested in Life Science and you are looking for a programme with ample opportunities to put together your own study path, our Life Science and Technology programme is the right choice. The programme focuses on societal problems at the molecular and cellular level.

On Friday 17 November at 15.30h Prof. Simon Deakin will give the first seminar of the Reform of Social Legislation Speaker Series

The Developmental and Educational Psychology unit nominated Jiemiao Chen's paper

Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel

Promotores: H.S. Overkleeft; G.A. van der Marel Co-Promotor: B.I. Florea

The polypept(o)ide hybrid material attracted more and more attention over the past decade by combining the multifunctional characteristics of polypeptides with the shielding characteristics of polypeptoid-pSar possessing similar properties as a shielding material as polvethylene glycol(PEG). Polysarcosine…

Microbial rhodopsins are photosensitive pigments implemented in the growth and adaptation of a large population of microorganisms.

Bacteria often experience external challenges, such as changes in environmental conditions or attacks by bacteriophages.

While bioinformatics methods deal with the analysis of sequence information (be it proteins or DNA), the field of cheminformatics is concerned with the analysis of small-molecule datasets.

In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.

The Business Studies specialisation is for science students who consider employment opportunities in industry, and who are looking to acquire knowledge of business principles and training in managerial skills. The specialisation can be followed by students doing a two-year Masters degree in one of…

Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt

Source: Mol Psychiatry (2015)

Nanodiscs are small, disc-shaped structures designed to mimic biological cell membranes, composed of a lipid bilayer stabilized by scaffold proteins. Membrane proteins play crucial roles in essential processes such as nutrient and waste transport, molecular recognition, and cell signalling, making them…

Synthetic cells, also known as artificial cells or protocells, have wide ranging applications from drug delivery vectors to cell models. In biotechnology they can function as micro- or nanoreactors with possible applications in biocatalysis and photocatalysis. Phospholipids are by far the most commonly…

Chapter 2 describes a post-synthetic methodology to introduce a fluorescent label in highly lipophilic, Pam3Cys based conjugates.

Artificial photosynthesis has recognised potential to produce green and sustainable fuels from earth-abundant resources such as water, carbon dioxide (CO2), and sunlight.

You’ve been accepted! Leiden University looks forward to welcoming you as a new student. Your next step is to prepare for your studies. Below you can find some tips to help you get a head start as you embark on your studies at Leiden University.

Conference

Promotores: Prof.dr. H. S. Overkleeft, Prof.dr. G. A. van der Marel

Phosphorylation affects all four major biomolecules – proteins, lipids, carbohydrates and nucleic acids – and plays a pivotal role in the most fundamental cellular functions.

This dissertation presents a new perspective on the life, work and character of the Dutch physical chemist Jacobus Henricus van ’t Hoff, first recipient of the Nobel Prize in Chemistry, and one of the most important and colourful scientists in Dutch history. The image of Van ’t Hoff that emerges from…

Source: J Cheminform, Volume 7, Issue 1 (2015)

Understanding how nature captures and transfers solar energy is essential both for elucidating biological photosynthesis and for guiding the design of artificial light-harvesting systems.

Do you have any questions about the Chemistry master’s programme? Please contact us!

Science Internship Fair, a Fair for students and companies to meet up for internships. Matching to find the right student for the right internship. information page for this event at LIACS.

Are you a PhD or postdoc at the Leiden Institute of Chemistry? Join our community to amplify your voice, grow professionally, and build lasting connections within our institute.

In a new essay for Ethics & International Affairs, Dr Henning Lahmann, Assistant Professor of International Law & Technology at eLaw, addresses the question whether states should resort to social media to warn a civilian population ahead of military operations.

Now online in Molecular Microbiology our studies on the motility of Sulfolobus acidocaldarius and its unique swimming organelle, the archaellum.

Are you interested in combining your Science master programme with the Education specialisation? Learn more and watch the introduction video.

Promotor: H.S. Overkleeft, Co-Promotor: B.I. Florea

Contact Medical Biochemistry

Peptides are routinely synthesized in the range of 5-80 amino acids, in an amount of 1-200 µmol (smaller and larger amounts are also possible).

From development of nanomaterials to advanced instrumentation and smart software systems, this specialisation empowers students to become a key player in tomorrow’s technological breakthroughs—through interdisciplinary research, industrial collaboration, and innovation-driven learning.

Within this thesis the central stage is taken by the discovery and investigation of transglycosylation of sterols. First, investigation focuses on the development of a method to accurately detect and quantify glucosylated metabolites in biological materials.

Are you interested in combining your master programme with the Science Communication and Society specialisation? Learn more and watch the introduction video.

Chemistry is all around us: from nutrition and smartphones to medicine. The field is developing rapidly, as the world population continues to grow and resources become scarce. MST will educate you on the basics of working towards a clean and healthy world.

The work described in this thesis focuses on the development of linear or cyclized peptide probes against protein N-methyltransferases to characterize their specific binding behavior, providing further binding details for inhibitory activity study.

This thesis describes research aimed at discovering inhibitors selective for either of the two endoplasmic reticulum α-glucosidases, ER-I and ER-II, with the overarching goal of discovering new antiviral agents to treat viruses that rely on host N-glycosylation for proliferation.