In the studies described in this study, we introduce a novel ex vivo human skin barrier repair model. To develop this, we removed the upper layer of the skin, the stratum corneum (SC) by a reproducible cyanoacrylate stripping technique.

This thesis investigated miniaturized mass spectrometry (MS)-based analytical methods to address challenges in analyzing biomass-restricted biological samples.

In this dissertation iron-based homogeneous catalysts were synthesized, characterized and investigated for water oxidation activity.

Of all the mass in our Universe, 80% is thought to consist of a hypothetical and invisible substance called dark matter (DM).

Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.

Spectroscopic studies on fluorescent single molecules in organic condensed matter does not only provide information about the molecule itself, but also its near environment. By suppression of phonon-induced broadening of spectral lines through cooling to low temperatures, small changes in the spectral…

Mouse models are commonly used to assess the immunogenicity of therapeutic proteins and to investigate the immunological processes leading to antidrug antibodies. The aim of this work was to develop a transgenic (TG) Balb/c mouse model for evaluating the immunogenicity of recombinant human insulin (insulin)…

β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…

How do Humanitarian Response Organizations (HROs) and Virtual & Technical Communities (V&TCs) collaboratively govern disaster sensemaking processes, and what challenges shape the effectiveness of these collaborations between 2010 and 2016?

This paper describes two synthetic lipid models designed to replace human stratum corneum (SC) in studies of the impact of volatile organic chemicals on the molecular organization of the skin barrier lipids.

This dissertation defends the existence of a type of movement that has so far been considered not to be possible, namely, movement of a bare head to a specifier position over arbitrarily long distances.

Organised in four separate sessions throughout the day, and broadcast live online to guests and families who could not join, a total of 260 students received their Bachelor’s Diploma of International Studies on 28 August 2020 at the graduation ceremony in the historic Pieterskerk in Leiden.

On Friday 22 November 2024 Ye Jiang successfully defended a doctoral thesis and graduated.

On Tuesday 3 September 2024 Straton Papagianneas successfully defended a doctoral thesis and graduated.

Current antibiotics only address very few target proteins in bacteria to kill them. Researchers know that there are more possible target proteins to tackle the bacteria. The question is: which ones. Thanks to the NWO Vidi Grant, Assistant Professor Molecular Physiology Stephan Hacker and his team can…

During a working visit to a company that cleans up space debris, the British Prince Charles suggested that a climate agreement specifically for space might be a good idea. Experts, including Leiden Law School’s Tanja Masson-Zwaan, say the idea is wishful thinking.

The International Court of Justice (ICJ) has commenced hearings on Israel’s ban on UN organisation UNRWA. Larissa van den Herik, Professor of Public International Law, commented on news programma NOS Nieuws.

This study aims to examine how South Korea (hereafter, Korea) and Japan, two neighboring countries in Northeast Asia, have been responding to and mitigating the spread of COVID-19.

The Security Studies bachelor's programme has received a bronze medal in EW Best Studies 2023. Every year, EW Best Studies selects the top programmes in Dutch higher education.

Organised in three separate sessions throughout the day, and broadcast live online to guests and families who could not join, over 200 students received their Bachelor’s Diploma of International Studies on 3 September 2021 at the graduation ceremony in the historic Pieterskerk in Leiden.

On Friday 16 May Juul Eijk successfully defended a doctoral thesis and graduated.

This research aims to investigate how different social forces interact with hydropolitics in the Eastern Nile Basin and what are the constraints of engagement.

Understanding others’ emotional behavior is essential for navigating daily social life. But how is such an understanding achieved? The eye-tracking study by Yung-Ting Tsou and colleagues shows that children with hearing loss adopt a unique visual strategy that makes uses of explicit visual information…

Promotor: Prof.dr. T. Schmidt, Co-Promotor: Dr. ir. S.J.T. van Noort

On 22 June, Anneke Koning defended the thesis 'Return to sender: a multi-method study of guardianship against transnational sexual exploitation of children'. The doctoral research was supervised by Joanne van der Leun, Masja van Meeteren and Johan van Wilsem.

On Tuesday 14 January 2025 Milan Ismangil successfully defended a doctoral thesis and graduated.

Are you keen to immerse yourself in a new culture, broaden your horizons and make friends for life? If so, come to the Study Abroad Festival on Friday afternoon 14 October.

Mapping sanitary infrastructure in large urban societies in the Low Countries, 1200–1900

When Henriëtte Hoffman was ten years old she was enthralled by The Last Emperor, a 1987 film about the twelfth and last emperor of the Manchu dynasty. It was an interest that eventually led to a five-month stay in Chengde in China for her Asian Studies research master’s programme. During her time in…

The collaboration between Leiden University (Medical Center) and the Autonomous University of Barcelona forms one of the most powerful international alliances for the creation and transmission of knowledge in the field of transfusion medicine.

What is students’ engagement in problem-based learning (PBL) and case-based learning (CBL) in teacher certification programs?

Part of ‘Moralising Misfortune: A Comparative Anthropology of Commercial Insurance’, an ERC Consolidator project of Erik Bähre.

On December 6th, 2024, Rector Hester Bijl welcomed participants at the Leiden Jewish Studies Association’s First Annual Conference “Jews at Home: From Creation to Corona” and also presented two Leiden University students with the inaugural Leiden Jewish Studies Association “Best Thesis in Jewish Studies”…

Tessa van Schagen and Naomi Sedney know exactly how to combine their Psychology study with top-level sport. Both students are running in the 4 x 100 metre relay at the Olympic Games. Van Schagen: 'Fellow students think it's great that I'm going to Rio.'

In the new Annual Report 2022 we report on not only research and teaching at Leiden University but also ICT, real estate, personnel, finance, impact and knowledge transfer and more.

The work done by SUMO proteins in the cells of our body is of vital importance. Molecular cell biologist Alfred Vertegaal has been studying these proteins for nine years, first with a Veni subsidy and then with a prestigious Vidi subsidy.

This study discusses the position of the monasteries in pre-1950s Tibetan societies and how that position was informed by Buddhist monastic ideology.

On Wednesday 20 November 2024 Sara Mirahmadi successfully defended a doctoral thesis and graduated.

A team of researchers at Leiden University’s Europa Institute authored an extensive study on the potential for a Climate and Energy Union within the EU constitutional framework. The study was published by the European Parliament in December 2024.

There are many complex links in the chain that provides patients with new drugs: from fundamental science, to clinical tests, to production. The entire chain can be found in Leiden. Leiden University, the Leiden University Medical Center (LUMC) and the businesses at the Leiden Bio Science Park (LBSP)…

In order to stop a whole range of diseases or disorders at their source, you would have to be able to switch certain genes on or off. Sebastian Pomplun wants to develop substances that can do this very precisely. For example, he wants to disrupt cancer processes and make cells produce an important missing…

Researchers from Leiden and Delft have found a way to look inside early-modern bookbindings. An x-ray technique has allowed them to search for remains of medieval manuscripts hidden inside the bindings. After the Middle Ages many manuscripts were recycled, their pages pasted inside bookbindings to provide…

Nanoparticles that transport medicines to a specific part of the human body are usually broken down in the liver prematurely. Jeroen Bussmann from Leiden University has discovered a new method to prevent this from happening. Publication in ACS Nano.