Wolves in the Netherlands mainly feed on wild animals such as wild boar and red and roe deer. But in areas such as Drenthe where these are scarce they also prey on free-roaming cattle used for nature conservation

How can chimpanzees, so closely related to humans, have almost no sense of rhythm? ‘The best students ever’ and behavioural biologist Michelle Spierings demonstrated that chimps can actually drum and move rhythmically—each following their own unique beat.

Anthropogenic noise negatively affects wildlife in a wide range of taxonomic groups.

The center studies the many ways in which issues of law and justice are dealt with in art and literature with a focus on liminal issues and cases. These are issues and cases where law comes to the limits of what it is capable of dealing with and art and literature explore the implications of what is…

‘Wadden Sea Sounds’ is the name of a new project launched by the Waddenvereniging in collaboration with researchers from Leiden University and the University of Groningen. The aim is to find out how underwater noise affects marine life in the Wadden Sea.

Before patients can take a pill, scientists often spend years in the lab developing and testing a candidate drug. That often includes experiments with laboratory animals. As head of the rodent facility, Ilze Bot and her colleagues ensure that these experiments are conducted in an ethically responsible…

PhD candidate Sibel Bahtiri is one of the new Faces of Science. In videos and blogs, she will show what life is like as a young researcher.

Lecture

PhD defence

We are transparent about our research involving laboratory animals, which includes providing access to our annual statistics. On this page, you will find an overview of various aspects, such as the number of animals and the species we use, the types of research for which we employ animals, and the level…

proefdieren dierproeven universiteit leiden geneesmiddelonderzoek geneesmiddelen

This book examines the role of memory in animation, as well as the ways in which the medium of animation can function as a technology of remembering and forgetting. By doing so, it establishes a platform for the cross-fertilization between the burgeoning fields of animation studies and memory studie…

We use zebrafish as a model organism to study human development and disease as well as animal welfare and environmental impact.

The project aims to explore Eurasian elk's role in the ecosystems of the past and its relationship with humans through analysis of its distribution and habitat in the Netherlands.

Acute stress seems to have a surprisingly positive effect on our health. Researcher Erin Faught received an NWO veni grant to find out why that is and how we can use that knowledge to our advantage. For her lab research, she uses a remarkable small animal to learn more about our own stress levels.

Fish populations in lakes and rivers have declined in recent decades. This is probably due to light and noise pollution. The Horizon Europe grant enables ecologist Hans Slabbekoorn to investigate this and improve the situation for migrating fish. In order to do so, a seven-metre-long swimming tunnel…

Personality is genetic in zebrafish: risk-taking parents have risk-taking children. These are the findings of research by Christian Tudorache and his team published in BMC Neuroscience.

Promotores: Prof.dr. P.C.W. Hogendoorn & Prof.dr. H.P. Spaink, Co-promotor: Dr. B.E. Snaar-Jagalska

Conference

Would you like to know more about our research using laboratory animals or our studies on alternatives to animal testing? If so, take a look at the news articles on the right-hand side of the page (for mobile users, see the bottom of the page).

Pharmaceutical companies, governments and the general public have become increasingly aware that animal models used in drug testing lack vital aspects to serve as an accurate representation of human biology. As models of the human body should become more physiologically relevant, animal models no longer…

In the Drug Research theme, we primarily work with rodents. Rodents, such as mice, are one of the most common laboratory animals. These small mammals are easily housed and exhibit a rapid rate of reproduction.

As a bachelor student of Bio-Pharmaceutical Sciences, Femke Vlaswinkel wrote a research proposal she was allowed to carry out in her master’s BPS. Femke subsequently graduated with honors. Her research was published in the journal Scientific Reports, she won an award from the Dutch Pharmacy Society…

PhD defence

Educators in European science museums sometimes think rather differently about the definition of an 'authentic' object. They think carefully about how they present those objects to teach visitors something or make them curious. This was shown in research by the Science Communication & Society department.…

In this thesis, I study 1) metabolic alterations in tuberculosis related to wasting syndrome in human patients as well as in rodent and fish animal models. 2) effects of the mutation of the leptin gene on cachexia and diabetes in rodent and zebrafish animal models.

If male budgerigars can successfully open a puzzle box with food, they become more attractive to females. Biologist Carel ten Cate and Chinese colleagues published experimental evidence for this in a paper in Science on 11 January. Various Dutch and international media wrote about the paper.

As humans we have a tendency to judge certain actions as either right or wrong. Where does our moral sense come from? We found evidence that infants who are only one year old prefer those who comfort as opposed to ignore another who is sad.

Proactive zebrafish appear to have a much stronger wake-sleep rhythm than reactive fish. In the most reactive fish, rhythmicity appears to be lacking completely. This is shown with research by Leiden biologists, published in December 2018 in the journal BMC Biology.

Herman Spaink knows of many substances that may help combat tuberculosis. Lab space to study them safely is very limited in Leiden. A brand-new lab at Universitas Gadjah Mada in Indonesia will soon provide a solution. About time, says Spaink, ‘The disease is on the rise and is becoming less sensitive…

How do young zebra finches learn to sing? A research team led by researcher Katharina Riebel has developed a ‘RoboFinch’ to study just that. She and colleagues in the 'Seeing voices' research consortium have spent the past four years designing the robotic bird. And with success: young zebra finches…

Promotores: C. J. ten Cate; M. A. Ainslie. Co-promotor: W. Slabbekoorn

During post-embryonic development into adults, animals face an environment that fluctuates constantly. For example, in nutrient availability, temperature, and osmolarity (e.g., salt concentration).

Promotor: Carel J. ten Cate, Co-Promotor: Hans W. Slabbekoorn

A new research line is the development of liquid biopsy fingerprints to predict early Alzheimer’s disease (AD) stage in human in readily accessible body fluids in human (in collaboration with: Dr. Geert-Jan Groeneveld, CHDR; Prof. Elga de Vries, Free University Medical Center; and others).

This project aims to develop advanced data analysis methods for monitoring and increasing our understanding on biodiversity dynamics in nature reserves such as the Oostvaardersplassen.

Avian Cognition describes the full range of avian cognitive abilities, the mechanisms behind such abilities and how they relate to the ecology of the species. Synthesising the latest research in avian cognition, a range of experts in the field provide first-hand insights into experimental procedures,…

Biologists today have to be able to work with big data. Data analysis skills should be taught from the start of the degree programme, or - even better - in secondary school. This is the message of Vera van Noort, new Professor of Computational Biology. Inaugural lecture 22 January.

A new treatment for atherosclerosis showed promising results in isolated cells but proved to be less effective in initial animal tests. Bachelor student Biopharmaceutical Sciences Willemijn van der Heijden aimed to understand why. She investigated whether the formation of a protein layer around the…

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