797 search results for “chronic kenney failure” in the Public website
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Too big to fool: moral hazard, bailouts, and corporate responsibility
On the 14th December 2016, Steven L. Schwarcz, Stanley A. Star Professor of Law and Business at Duke University School of Law gave the thirteenth Hazelhoff Guest Lecture. Professor Schwarcz questioned the often-heard assumption that systemically important financial institutions engage in excessive…
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Healthy ageing
The elderly accept may minor discomforts like stiffer muscles and getting tired more quickly, but they do want to go to their children's birthdays independently. Preventive elderly care helps people with that. The goal is to let people grow old while maintaining their self-reliance and independence…
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Transboundary Crisis Management Capacities of the European Union
This project investigates the capacities of EU institutions to coordinate the responses of member states to critical events.
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Application of zebrafish and murine models in lipoprotein metabolism and atherosclerosis research
Cardiovascular diseases are still a major concern for the global health.
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Topic: Work and health
The research connected to this topic is related to Work and health.
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Therapeutic Immunomodulation
The Therapeutic Immunomodulation Group is led by Prof. Johan Kuiper. In this group we aim to identify novel immunologic targets and apply immunotherapy to inhibit or even prevent the development of atherosclerosis.
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Health promotion and resilience
This focus area centres on promoting health and stimulating the physical, mental and social resilience of citizens.
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Transformations in global climate finance
Climate finance, especially for developing countries, is crucial for limiting global warming to 1.5C. However, the current level of North -South climate finance is chronically inadequate. As the climate crisis intensifies, more actors are entering the climate finance market, transforming the global…
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Bernet ElzingaFaculty of Social and Behavioural Sciences
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New imaging technology to assess early drug success
Human and animal cells are very complex: very different chemical processes are going on at the same time, but they are separated from each other because the cells are divided in compartments. These compartments may also have a profound effect on the potential efficacy of therapeutics, because the drug…
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Eduard Fosch-Villaronga & Louk van Doorn win the DT4REGIONS Ideathon on AI Potential for Preventive Healthcare
eLaw - Center of Law and Digital technologies from Leiden Law School, and the Vascular Surgery Department at Leiden University Medical Centre in the Netherlands, join forces to explore the use of AI for diabetes and secondary prevention of diabetic foot problems and won a prize for it.
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Contracts and supplies
Find out about the effects of Brexit on contracts and supplies.
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The UN’s Summit of the Future: Advancing Multilateralism in an Age of Hypercompetitive Geopolitics
In this article, Joris Larik and Richard Ponzio grasp the importance of the Summit of the Future to overhaul and strengthen multilateral cooperation in an age of deepening rifts and increasing competition between the great powers. This article argues that a failure to convene a meaningful and ambitious…
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Imperfections: using defects to program designer matter
Errors are everywhere, and mechanical failures are especially common: buckled grain silos and cracked support columns are, justly, seen as an issue to be avoided.
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The archaeology of imperial landscapes
The Archaeology of Imperial Landscapes examines the transformation of rural landscapes and societies that formed the backbone of ancient empires in the Near East and Mediterranean. Through a comparative approach to archaeological data, it analyses the patterns of transformation in widely differing imperial…
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Politics of Withdrawal Media, Arts, Theory
'Politics of Withdrawal' considers the significance of practices and theories of withdrawal for radical thinking today.
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Who is to blame? Stories of European Union migration governance in Italian, Maltese, and Spanish newspapers
The article examines how Southern European member states' newspapers portray European irregular migration governance.
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Placebo research: Pharmacological conditioning
The major aim is to examine the potential of learning the body to produce a similar physiological (autonomic, neuroendocrine, or immune) and physical (e.g., desensitization of persistent physical symptoms) response to placebo medication than to active medication (pharmacological conditioning). If proven…
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Influencing your health with your behaviour and thoughts
Psychological processes have a major effect on the course of a disease and the effects of medical treatment. Researchers in the field of Psychoneurobiology examine the interactions between body and mind. They investigate the effects of stress as well as the effect of placebos and nocebos, which can…
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Migraine@Work: work ability in employees with migraine
This study aims to answer two main research questions: (1) What are the main predictors of work ability in employees with migraine? (2) Can we optimise work ability in employees with migraine using a web-based intervention focused on these relevant predictors?
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Call for Participation online workshop Interrogating Speculative Futures
Call for Participation for the online workshop Interrogating Speculative Futures: A workshop on the politics of imagining a future with(out) chronic illness on 19 and 20 July 2021.
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Lifestyle and nutrition to combat diseases (of affluence)
We know this, but we don’t act on it: eat healthily, move more, address our stress levels and sleep well. Internist and Professor of Diabetology Hanno Pijl is fascinated by the effect that a healthy lifestyle can have on health. He researches how this lifestyle is achievable and satisfying, for patients…
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Open label placebo for itch
Positive expectations can influence sensations of itch and evoke placebo effects, whereas negative expectations can trigger nocebo effects in itch. There is evidence that placebo effects can occur even when people know that they are taking a placebo. Little is known about how these so-called open-label…
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Health, Ageing and Society (MSc)
Master's Health, Ageing and Society: tackle ageing population, innovating and improving elderly care, care for ageing population, health systems, wellbeing & policy. Improve elderly care, Prepare for future healthcare and societal challenges.
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Stress-induced modulation of the innate immune system in cardiovascular disease
Promotor: Prof.dr. J. Kuiper
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CD8+ T-cells in atherosclerosis, recognizing their contribution
Atherosclerosis is the most prominent underlying pathology of cardiovascular disease and an important cause of major adverse cardiovascular events.
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Topic: Spatial thinking
Our everyday life consists of all sorts of spatial processes: we find our way to work, remember where we left our keys, and are able to pick up our cup of coffee. We study how the human brain processes such spatial processes. From a clinical perspective, we are interested in how acquired brain damage…
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A₃ adenosine receptor allosteric modulator induces an anti-inflammatory effect: in vivo studies and molecular mechanism of action
Source: Mediators Inflamm (2014)
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Carcinogenicity of insulin analogues
Promotor: Prof.dr. B. van de Water, Co-promotores: J.W. van der Laan, C.L.E. Siezen
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The interplay between lipids and the immune system in atherosclerosis
Cardiovascular diseases are among the most frequent causes of death in the world. The main underlying pathology of cardiovascular diseases is the development of atherosclerosis in the medium and large-sized arteries.
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Pharmaceutical Aspects of Subvisible Particles in Protein Formulations
Promotor: W. Jiskoot, Co-promotor: A. Hawe
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Health, Medical and Neuropsychology
The unit Health, Medical and Neuropsychology offers eduction and conducts research on related fields of Health, Medical and Neuropsychology.
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Synthesis and application of glycans unique to S. Mansoni
Schistosomiasis is an acute and chronic disease caused by blood dwelling parasitic trematodes of the genus Schistosoma, and it is classified as the second most socioeconomically devastating parasitic disease, second only to malaria.
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Analysis of sub-visible particles in complex injectable formulations
Promotors: W. Jiskoot; G.J. Witkamp, Co-promotor: M.R. Nejadnik
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Vaccination against atherosclerosis; induction of protective CD8 T-cells through immunization
Atherosclerosis, in particular rupture of atherosclerotic plaques, is the underlying cause of most heart attacks or strokes and is the leading cause of death worldwide.
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B cell modulation in atherosclerosis
Cardiovascular disease is a major global burden and atherosclerosis is the main underlying pathological process.
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Cholesterol metabolism and hematopoiesis interaction in atherothrombosis
Cardiovascular disease is the leading cause of death worldwide.
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Innate immune modulation in atherosclerosis and vascular
Promotores: Prof.dr. J. Kuiper, Prof.dr. P.H.A. Quax
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HOPES Study
The HOPES study is one of the largest investigations of this kind to date! By studying existing brain scans and data collected form over 4,000 14-25 year olds, the project team hopes to identify specific changes in the brain that make young people vulnerable to suicidal thoughts and behaviours.
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Key publications
Key publications of the Analytical BioSciences and Metabolomics group
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Mast cells as immune regulators in atherosclerosis
Cardiovascular syndromes are the major cause of death in Western societies.
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The role of the interleukin 12 family in atherosclerosis
Promotor: Prof.dr. J. Kuiper, Co-promotor: Saskia C.A. de Jager
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Vivian Kraaij
Faculty of Social and Behavioural Sciences
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Warnings: The Complicated Journey from Alert to Action in (Inter)national Politics (WARN)
The WARN project seeks to understand why certain warnings fail to reach and impact decision makers in time to avert crisis.
- Parliamentary Diplomacy
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International Coalitions for Peace in the Era of Decolonization, 1918-1970
International Coalitions for Peace in the Era of Decolonization, 1918-1970
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OFAC, Famine, and the Sanctioning of Afghanistan: A Catastrophic Policy Success
Matthew Hoye argues for a regulatory analytical perspective to look at the sanctioning of Afghanistan.
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Chemical biology of glucosylceramide metabolism fundamental studies and applications for Gaucher disease
This thesis describes biochemical investigations of glucocerebrosidase (GBA), the lysosomal β- glucosidase that is deficient in Gaucher disease (GD).
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Optimizing antifungal treatment through pharmacometrics: dosing considerations to enhance outcome
Fungal infections pose a significant threat to individuals with compromised immune systems and despite advancements in diagnosis and treatment, they continue to jeopardize patient’s health.
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EU Bank Resolution Framework: A comparative study on the relation with national private law
On 19 September 2019, Lynette Janssen defended her thesis 'EU Bank Resolution Framework: A comparative study on the relation with national private law'. The doctoral research was supervised by Prof.mr. W.A.K. Rank and prof. M. Haentjens.