Through his project we will unravel the global regulatory networks that control gene expression in Streptomyces bacteria and allow them to properly respond to major changes in the environment; we will then harness this knowledge to activate and identify novel antibiotics

Mr. Sujadi defended his thesis on 29 June 2017

The central aims of this project are to establish the shapes of the various urban hierarchies existing in the provinces of the Roman Empire and (especially) to use the quantitative properties of these hierarchies to shed new light on levels of economic integration.

In an age before GoogleDocs and LinkedIn, 19th-century scholars relied on letter-writing for collaboration, peer-feedback and the building and sustaining of academic networks. Letters were a quick, efficient way to share insights, data and discoveries. Scholarly correspondence thus allows a vital behind-the-scenes…

This thesis pioneers diatom molecular identification and quantification through genome-scale methods, with four key aims: (i) reviewing DNA/RNA sequencing methods in aquatic biomonitoring to highlight their strengths and limitations;

Beyond Empires explores the complexity of empire building from the point of view of self-organized networks, rather than from the point of view of the central state.

Diacylglycerol lipases (DAGLα and DAGLβ) convert diacylglycerol to the endocannabinoid 2-arachidonoylglycerol. Our understanding of DAGL function has been hindered by a lack of chemical probes that can perturb these enzymes in vivo.

One of the major limitations in culturing complex tissues or organs is the lack of vascularization in the cultured tissue. Development of a functional capillary bed could overcome this problem.

The Data-Driven Drug Discovery Network (D4N) is an initiative by researchers from Leiden University and collaborators to join efforts in applying and developing novel techniques from data science to drug discovery and related topics from bioinformatics.

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This dissertation presents four separate chapters, all striving towards the same goal: to understand dynamic phenomena occurring in dynamic networks and to explore the emergence of equilibrium in a broad sense.

How was anti-communism organized in the West? New volume edited by Giles Scott-Smith, Luc van Dongen and Stephanie Roulin on the aims, arguments and associations of a range of transnational anti-communist activists during the Cold War.

Building off the success of the 'Jews at Home' conference in December 2023, the Leiden Jewish Studies Network convened its second conference 'Care and the Jewish Experience' this past September in Leiden.

Building a Deep Cross-media Transfer Network to extract visual relations that relieve the problem of insufficient training data for visual tasks.

This thesis describes a study from both a theoreticaL and an experimental point of view.

This interdisciplinary study focuses on (trans)national ethnic and popular networks, combining historical-ethnographic and computational methods to understand the ‘workings’ of networked conflict interfering in the increasingly violent conflict in the Sahel (Africa) and beyond. The project focuses on…

The Gravitation programme NETWORKS has been awarded a COFUND grant of 3 million euros. Half of this comes from the European Commission's Marie Skłodowska-Curie Actions programme, with industry partners paying the other half. Of the fourteen new PhD candidates, two will join Frank den Hollander's research…

The financial system needs complexity theory to predict economic crises like the 2008 meltdown. An international team of scientists, including Leiden physicist Diego Garlaschelli, state this in a paper published in Science on February 19th.

Imagining Urban Complexity introduces passionate and critical perspectives on the link between the humanities and urban studies.

This thesis explores how bees and hoverflies are distributed across the Dutch landscape and how ecological and landscape factors shape their occurrence.

Renate Dekker defended her thesis on 7 November 2017.

On November 24, 2017, Esther Keymolen gave a presentation on Trust in the Networked Era, as part of the annual Philosophy of Technology Lab. This lab is organized by a.r.t.e.s. Graduate School for the Humanities Cologne and CFCU (Centro de Filosofia das Ciências da Universidade de Lisboa). The general…

The central issue of this research concerns how students can best be supported in their study choice, study career and future orientation with a view to flexible entry and transitions and perspective in education and work.

The modern-day Caribbean is a stunningly diverse but also intricately interconnected geo-cultural region, resulting partly from the islands’ shared colonial histories and an increasingly globalizing economy.

Imagine getting a notification on your mobile phone with your personal code for impending mental health problems or even depression: yellow, orange, or red. Science fiction? Not for scientist Eiko Fried. 'There is a real chance we can prevent some mental health problems before they occur.' Want to participate…

Complex systems can be characterized as systems in which multiple components interact with each other, often in non-linear ways. The main goal of this research will be to investigate if and how the international tax system can be defined and modelled as a complex system. Approaching the international…

Promotor: A. Doelman, Co-promotor: V. Rottschäfer

Multicopper oxidase, laccase, can efficiently reduce oxygen to water and are mostly used in the enzymatic biofuel cells.

Promotor: Prof.dr. E. Bouwman

The Gulf is a major global destination for migrant workers, with a majority of these workers coming from South Asia. In this book, a team of international contributors examine the often-overlooked complex governance of this migration corridor. Going beyond state-centric analysis, the contributors present…

Explaining treatment response variability between and within patients can support treatment and dosing optimization, to improve treatment of individual patients.

Back after pandemic interruptions, the Dutch Network Science Society Symposium took place on May 19th, 2022. The event brought together researchers from around The Netherlands studying complex networks and representing various disciplines, including mathematics, physics, neuroscience, computer science,…

The principle aim of the project is to study the genesis and the quantitative properties of the Early Roman urban network of the Balkan and the Danube provinces.

Jifeng Liu defended his thesis on 2 February 2017

Policy Note Insecurity in Burkina Faso – beyond conflict minerals: The complex links between artisanal gold mining and violence

Since the emergence of humankind people have maintained social contacts and traveled widely, establishing interaction networks in which goods are traded and ideas are transmitted, increasingly on a global scale.

The mechanism of the electrochemical reduction of dioxygen by a mononuclear pyridylalkylamine copper complex was investigated (see picture). It was shown that in neutral aqueous solution dioxygen undergoes stepwise reduction, wherein hydrogen peroxide plays a key role. The rate constants determined…

What contributes to the successes and failures of governance networks in small to medium-sized Western European host cities in attracting International Organizations?

The project investigates the changing local context of crime dynamics and the responses by selected international organizations and national governments. It places a major emphasis on security management at the trans-national level by investigating intra-regional security cooperation between Latin America,…

How can pupils and students learn to get a grip on complex 'swamp situations'? Inaugural lecture in abbreviated form held by prof.dr.ir. Fred Janssen on the acceptance of the post of professor of science education at Leiden University on 19 June 2017.

EnSMiRT seeks to harness expertise within the Una Europa alliance and foster collaborations between leading researchers working on several stages of the mineral value chain to address these pressing challenges head-on.

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How do plants lure microscopically small 'support teams' into their roots for protection against diseases? And what functions are activated in the microbes and the plants?

Promotor: Ed F. Deprettere, Co-promotor: Todor P. Stefanov