1,268 search results for “novel” in the Public website
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Globalisation and the Roman world
World history, connectivity and material culture, edited by Martin Pitts and Miguel John Versluys. From Cambridge University Press.
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Aging and Immunity
The Aging and Immunity group is led by Dr. Amanda Foks. In this group we aim to investigate how aged immune cells contribute to atherosclerosis and identify novel therapeutic targets and strategies to extend health span and inhibit cardiovascular disease.
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Guram Odisharia: Literary responses to the Abkhaz-Georgian conflict
Arts and culture, Q&A
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Quantitative pharmacology approaches to inform treatment strategies against tuberculosis
Tuberculosis (TB) is associated with 1.5 million deaths annually. There is a need exists to optimize both current as well as novel antibiotic combination treatment strategies to improve the effectiveness and safety of treatments against TB.
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Bioactive Molecules
All living systems are assembled from nature’s repertoire of small, medium, and large organic molecules. This theme focuses on the study, discovery and development of novel bioactive compounds obtained from biodiversity. We aim for new insights into the role of these molecules in the natural environment,…
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Optimality
Optimality in plant properties and processing.
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Graphic Novels in South-Africa: the Work of Nathan Trantraal
Arts and culture
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Nora BrüchleFaculty of Science
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PhD Theses
A full overview of MCBIM PhD theses.
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Research
At the division of Biopharmaceutics, we aim to develop and test new therapeutic approaches to limit or even prevent the development of atherosclerosis in order to reduce the number of acute cardiovascular syndromes such as myocardial infarction or stroke.
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Research in Bio-Pharmaceutical Sciences (MSc)
In the Research in Bio-Pharmaceutical Sciences specialisation you will perform research on various topics in the area of Drug Discovery and Development. The programme offers a high level of flexibility and can be tailored to your scientific interests. The major research project is hosted by the Leiden…
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The promise of bureaucratic reputation approaches for the EU regulatory state
Reputation literature has provided crucial insights about the evolution of the US regulatory state. Daniel Carpenter’s influential account painstakingly demonstrates the relevance of reputation to bureaucratic ‘power’ and to early institutional state-building in the US context. We argue that adopting…
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Game Research Lab
The Game Research Lab uses digital games as a medium for academic research. It considers entertainment games and 'serious’ games as objects of study, develops novel approaches for creating, playing, and analysing games, and studies the interactions between games and AI.
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Potentiation of Gram-positive specific antibiotics against Gram-negative bacteria through outer membrane disruption
Extending our current arsenal of antibiotics is key to staying ahead in the arms race between humans and resistant bacteria.
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Towards the development of synthetic vaccines against tuberculosis
The research described in this Thesis was aimed at designing and synthesizing nature-inspired compounds as part of TB vaccine discovery.
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Search and rescue: tackling antibiotic resistance with chemistry
With the rise of multi-drug resistant bacterial pathogens, the possibility of a post-antibiotic world is quickly becoming reality.
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Turtles all the way down: multiscale simulations connecting star and planet formation
The formation of stars and planets happens over multiple scales, which can interact. In particular, planet formation happens in the dense, complex environment of star forming regions.
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Liposomes as delivery system for allergen-specific immunotherapy
In this book liposomes are explored as delivery system for allergen-specific immunotherapy. Both cationic and anionic formulations are prepared with Bet v 1, one of the allergens in birch pollen.
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Bio-inspired Computing
We investigate reaction systems, a novel computational model gleaned from the biochemical reactions taking place in living cells and information processing in nature.
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Large-scale Computing Infrastructure
Large-scale computing infrastructure, such as supercomputers, cluster, and clouds, are already pervasive, most members of our society interact with them daily: social networks, government services, media streaming services--all systems heavily interfacing with the members of our society--are powered…
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Immunotherapy to limit atherosclerosis-projects
For more information regarding ongoing research projects, please contact Prof. Johan Kuiper.
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Algorithm for Structural Variant Detection
Structural variants (SVs) are the hidden architecture of the human genome, and are critical for us to understand diseases, evolution, and so on.
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Biomedical Imaging
The rapid advances in imaging technology enable to see inside the body with ever increasing detail.
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Post-Soviet Nostalgia. Confronting the Empire's Legacies
Bringing together scholars from Russia, the United States and Europe, this collection of essays is the first to explore the slippery phenomenon of post-Soviet nostalgia by studying it as a discursive practice serving a wide variety of ideological agendas.
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Conversations of Motherhood
The subject of motherhood is interwoven with themes of survival, power and identity. It is also at the heart of any consideration of women’s writing. Conversations of Motherhood sensitively charts common themes, intersecting experiences and related topics within the cultural specificities of South African…
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Film and Literary Studies (BA)
Do you enjoy a great story? In the Bachelor's programme Film and Literary Studies at Leiden University you study the stories behind the stories. Because what makes a novel fascinating or a horror movie frightening? Study film, literature and media from around the entire world and discover the differences…
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Vision and Mission
The need for novel drugs as well as innovations in their development and application is as urgent as ever. Below we present our vision , mission, and our key research areas.
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Health research and expertise at the IBL
We investigate the molecular basis underlying health and disease and provide answers to existing and emerging health problems. Within this theme, we study diseases ranging from rare genetic disorders to cancer and infectious diseases. We make use of a wide variety of model systems and pursue diverse…
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Research
The current projects of the Molecular Physiology group focus on proteins of the endocannabinoid system, kinases and antibacterial targets. MSc- and BSc-students can contact Jessica van Krimpen-Kraaijenoord to apply for research internships.
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Literature and Spaces of Conflicts: The Lebanese War Novel as Urban and Architectural History
Lecture, LUCIS What's New?! Series
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WISE Horizons
To facilitate and accelerate a systemic change in society by creating a framework based on the current post-growth narratives, policies, and initiatives.
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Molecular Pharmacology
In this research group, headed by Laura Heitman, novel receptor concepts in drug discovery are studied, aiming to increase the effectivity of medicines. Many drugs act via so-called G protein-coupled receptors (GPCRs) and therefore our research is mainly focused on understanding and improving drug-receptor…
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TRAFIG: Transnational Figurations of Displacement: Connectivity and mobility as solutions to protracted refugee situations
How can we promote more durable solutions to protracted refugee situations and which roles can connectivity and mobility of displaced people play to improve protection and resilience?
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The Implications of ISIS (the “Islamic State”) for Islamic Movements and the Middle East
Political Islam is not new to the Middle East, but the appearance of ISIS has stretched the phenomenon to the extreme.
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Proteochemometrics
Research question
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Pursuing new anti-cancer therapy as a team
Cancer is the leading cause of death in the Netherlands, and, with over 100 different types of cancer, it’s not a simple disease. Today, skin, breast, lung, prostate and colon cancer are the most diagnosed forms. Therefore, the discovery and development of new drugs has the ability to significantly…
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Delivery of Biotherapeutics
The Delivery of Biotherapeutics research group is led by Prof. Matthias Barz and focusses on the synthesis and characterization of polypept(o)ids and their application in nanomedicine to improve existing therapies or enable novel diagnostic or therapeutic approaches.
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Cell Systems and Drug Safety
The research within the Division of Cell Systems and Drug Safety, headed by Prof. Bob van de Water, is focused on novel therapeutic modalities and novel concepts in early drug discovery, in order to develop more effective and safer therapeutic strategies. We generate advanced cell and computational…
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Research project: Unravelling the Rule of Law
While acknowledging prominent legal-philosophical debates, this project proposes a radically different approach to provide insights into the concept of the rule of law.
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[sbb] INSCONS: International Scientific Consortia
Addressing Global Challenges through International Scientific Consortia
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MARBLES - Marine Biodiversity as Sustainable Resource of Disease-Suppressive Microbes and Bioprotectants for Aquaculture and Crop Diseases
To explore the potential of marine microorganisms as producers of novel antimicrobial agents and as bioprotectants in aqua- and agriculture, using an integrative, ecology-based strategy for bioprospecting.
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Immunotherapy to limit atherosclerosis
Atherosclerosis is a chronic inflammatory disease, and vaccination may be an attractive method to induce long lasting protection against endogenous factors that contribute to the development of atherosclerosis. We have shown that for example vaccination against modified LDL or interleukin-12 limits…
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Topic: Novelty and enrichment
One of the most crucial aspects of our behaviour is our motivation to explore novel environments and interact with new people. This became painfully clear during the COVID-19 lockdowns, when many people suffered from lack of new experiences and real-life social interactions. The relevance of novelty…
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High-Throughput Metabolomics
Development of Comprehensive and High-throughput metabolomics techniques and Clinical applications of (pharmaco)metabolomics
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Computational Approaches to Disease, Signaling and Drug Targets
The Minor Computational Approaches to Disease, Signaling and Drug Targets (CADSDT) is focused on fundamental scientific research required for discovery of new drug targets and development of new drugs.
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Book Discussion: Mai Serhan & Youssef Rakha: I Can Imagine It for Us
This lecture will be hosted on Thursday, 6 November 2025 at 6:00 pm.
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Cuba
This is an Erasmus+ International Credit Mobility project of Leiden University Medical Center with the University of Havana.
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Research themes
The Institute of Biology Leiden (IBL) is an internationally oriented institute for research and education in biology.
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Education
The specialisation High-Tech Innovation is for MSc students in Sciences who are interested in interdisciplinary technologies and research related to /important for high technology industries, e.g. the semi-conductor industry or nano-fabrication.
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Leiden Early Drug Discovery & Development
Despite recent advances in medicine, many devastating disorders like cancer and cardiovascular, neurodegenerative and infectious diseases still lack effective treatments. In order to address this challenge, we, as scientists from Leiden University, joined hands in the LED3 network. LED3, for Leiden…