A new mathematical model may explain how body cells get their shapes and what makes them move within a tissue. The model provides fundamental knowledge for applications in tissue engineering, amongst other things. Publication in open-access journal iScience.

Zebrafish-human communication shows that cancer cells lacking a signaling protein are less able to develop aggressive metastatic properties. This discovery has been made by molecular cell biologist Claudia Tulotta. PhD defence 14 June.

This monograph, written by dr. Dennie Oude Nijhuis and published by Cambridge University Press, discusses the postwar development of the welfare state.

Many teachers in secondary education take differences between pupils into account . PhD research by Saskia Stollman (ICLON) shows that they need room to experiment and the support of the school management

Promotor: Prof.dr. P. Hooykaas, Co-promotor: Dr. R. Offringa

This article offers an inaugural assessment of how silences implicate international law-making in cyberspace through descriptive and normative lenses.

The life of a fibroblast is heavy, but PhD student Julia Eckert makes it 19.5 times heavier, using the Large Diameter Centrifuge at the ESTEC space research centre in Noordwijk.

Antoaneta Dimitrova, Professor Comparative Governance at Leiden University, Honorata Mazepus, Assistant professor at Leiden University and Dimiter Toshkov, Associate Professor at Leiden University, together with three other authors researched which aspects of state capacity might contribute to opening…

A discourse on international cyber norms has emerged ever since the United Nations Group of Governmental Experts on Developments in the Field of Information and Telecommunications in the Context of International Security (UN GGE) recommended eleven norms on responsible state behaviour in cyberspace.

On 16 June 2020, Andrea Varga defended her thesis 'Establishing State Responsibility in the Absence of Effective Government'. The doctoral research was supervised by Prof. N.J. Schrijver and Prof. F. Baetens (University of Oslo).

Organisations such as the EU are of enormous benefit to the member states, but the inhabitants of the member states are often unaware of this. Leiden researchers investigate whether international organisations such as the EU or ASEAN are able to influence global politics.

On 27 June 2019, Vid Prislan defended his thesis 'Domestic Courts in Investor-State Arbitration: Partners, Suspects, Competitors'. The doctoral research was supervised by Prof. dr. N.J. Schrijver.

Slavoj Žižek is one of the most prominent public intellectuals of the left. His central claim holds that “today, it is more crucial than ever to continue to question the very foundations of capitalism as a global system”.

State utilization of 'hukum adat' and its implication for the Indonesian rule of law

The main aim of this thesis was to unravel the signaling and regulatory networks that drive tumor cell migration during breast cancer metastasis.

Viral hemorrhagic fever (VHF) is a group of acute diseases caused by highly infectious viruses including Ebola, Lassa, Dengue viruses. Its high mortality rate poses high risk to public health, however, studies on VHF have been hampered due to the non-availability of proper models and incomplete knowledge…

Chemist Roxanne Kieltyka has received an ERC Starting Grant of 2 million euros. In her lab, she creates gels that mimic the instructive material that supports cells in our body. With the grant, she aims to make these gels stiff and tough, and to create a bio-printed miniature heart ventricle.

In this article, Kuipers and Timmermans analyze the first lady's relationship with policy problems in the period 1945-2013.

This dissertation contains four works during my PhD. Different biomaterials have been designed based on coiled-coil peptides. These biomaterials have a range of applications, inclusing drug delivery, cell sorting to cell-cell fusion.

During the 1980s and early 2000s, authors like Alex Schmid and Andrew Silke demonstrated the paucity of first-hand insights being used to study terrorism and the consequences this had for the reliability of the findings beings presented. But to what extent have these issues endured?

Cardiovascular diseases are a leading cause of death worldwide, and better models are urgently needed for disease progression studies and drug development.

Multicellular giant algae Chara species have been widely used in physiological studies for decades.

Carbohydrates are present on the surface of bacteria making them suitable antigen candidates for vaccine development. This thesis deals with the synthesis of two carbohydrate-based components; the capsular polisaccharide of S. aureus type 5 and teichoic acids from staphilococci and enterococci speci…

PhD defence

The overall theme of this thesis is to complement the electrochemical data acquired in fuel cell research with in situ X-ray photoelectron spectroscopy (XPS) and soft X-ray absorption spectroscopy (XAS).

Biophysicist Rolf Harkes has developed a microscope to optically localize individual molecules in living cells. It improves monitoring of diseases like cancer and Parkinson’s at the cellular level. Defende PhD thesis on t13 January 2016.

This book offers novel perspectives on the national and international dimensions of the post-war welfare state in Western Europe and North America.

Prison staff are working under high pressure. The current proposal for cell sharing is the final straw. Associate Professor Esther van Ginneken appeared on Dutch news programme ‘Nieuwsuur’: ‘Serious incidents have occurred, including the murder of a cellmate.’

Embryonic stem cells have the remarkable ability to develop into any type of cell. On their way to become for example a liver or a heart cell, they must repeatedly decide between alternative developmental paths. How they make these decisions is largely unknown. An international team of biophysicists…

Advancing the understanding of the interaction of light and matter on the single-quantum level is important for near-future quantum technologies but also to answer fundamental questions.

The research project ‘The History of National Security, 1945-present', is funded by the Netherlands Organisation for Scientific Research (NWO), the Campus The Hague/Leiden University and the Netherlands Institute for Military History (NIMH). The project will run until the summer of 2013, when we hope…

Promotor: Prof.dr. J. Kuiper, Co-promotor: Saskia C.A. de Jager

Huub de Groot is professor in Biophysical Organic Chemistry. With his team he works in the field of photosynthesis and artificial photosynthesis. The molecular basis for photosynthesis is formed by protein complexes and organelles that contain chlorophyll molecules. The antenna systems herein capture…

The focus of the described research in this thesis is on the oxidative stress response (Nrf2 pathway). The aim of the research presented in this thesis is to obtain more information concerning microRNAs which are involved in the Nrf2 pathway, to determine and evaluate the application of microRNAs for…

Leiden molecular cell biologists in the research group of Annemarie Meijer have discovered novel early macrophage-specific genes in zebrafish, including a signal transducer pivotal for the migration of macrophages in the innate immune response to bacterial infection. Their findings were published on…

This project aims at providing a broad perspective of the state of Science Technology and Innovation (STI) in Africa with a focus on global funding flows, in order to inform research funders in the continent, in particular those participating in the Science Granting Councils Initiative (SGCI). The project…

The adsorption of D2 and CO2 on catalyst surfaces is studied using a molecular beam in ultra-high vacuum.

Leiden chemists, together with colleagues at the University of York (UK) and Technion (Israel) have discovered a small, sugar-like molecule that maintains the integrity of tissue around a tumour during cancer. This molecule prevents tumour cells from spreading from the primary cancer site to colonise…

Leiden physicists are helping Wageningen plant researchers to study unpredictable plant embryos. For this, they are using a novel two-photon fluorescence microscope, aided by a 30 thousand euro ZonMW grant.

An international group of scientists has discovered that certain cells of our immune system – the so-called T cells – communicate with each other and work together as a team. To fight an infection they stimulate each other’s growth, but at the same time, they inhibit each other when there is a surplus…

With the necessary measures, researchers restart their work in various laboratories. The Leiden Cell Observatory is one of the places where scientists resume their lab work.

This edited volume provides a synthesis on the question of business attitudes towards and its influence over the development of the modern welfare state. It gathers leading scholars in the field to offer both in-depth historical country case studies and comparative chapters that discuss contemporary…

When the immune system attacks cancer, the tumour modifies itself to escape the immune reaction. Researchers at LUMC published on this subject in Nature on 28 June.