Many metalloenzymes that are key to bioenergetics are membrane enzymes, with canonical examples the complexes I, II, III and IV in the mitochondrial inner membrane. To study these enzymes in a native-like lipid membrane environment, we aim to develop novel bioelectrochemical techniques.

Physicists at the Leiden Institute of Physics (LION) conduct fundamental research into physical phenomena. They are inspired by curiosity and the desire to know more about the world in which we live. This research has always paved the way for new practical applications. These are something that the…

Promotor: A.P. IJzerman

International Relations and European Politics is one of the three organisational clusters of the Institute of Political Science.

In a new video lecture (in English) on Universiteit van Nederland, astrophycisist Yamila Miguel tells us about the discovery of the most bizarre planets outside of our solar system.

LED3 is the combined effort of three excellent institutes of Leiden University. Through joined hands, we are able to give rise to a more effective early drug discovery pipeline. Let us briefly introduce the three institutes.

Through metabolism, biochemical processes give rise to the complexity of life. Acquired and inborn errors in metabolism underlie many diseases occurring in man. The challenge for present day medical biochemistry is to find, and integrate, pieces of information at molecular, cell and organismal level…

This long term project in Jordan is at the basis of many specialists’ studies and has several off-shoot projects. The project, with its many approaches, is also a framework for much teaching in Levantine Archaeology at Leiden University, especially concerning fieldwork methods, artefact studies, research…

A full overview of MacBio PhD Theses.

Promotor: A.P. IJzerman Co-promotor: L.H. Heitman

The Van Loon project sets out to safeguard the archives of Dutch archaeologist Maurits van Loon (Amsterdam, September 22, 1923 - Montpellier, October 12, 2006) and make them accessible for further study.

The current projects of the Molecular Physiology group focus on proteins of the endocannabinoid system, kinases and antibacterial targets. MSc- and BSc-students can contact Jessica van Krimpen-Kraaijenoord to apply for research internships.

Drug development is a time- and resource-consuming process that starts with the discovery and validation of a (protein) target that contributes to pathogenesis or disease progression.

In 1993, Prof.Dr. L.J. Slikkerveer was appointed as Chairman of the Pithecanthropus Centennial Foundation, commemorating the centenary of the discovery of ‘Java Man’ (Pithecanthropus erectus) by Eugène Dubois in 1893 in Trinil, Java, Indonesia with an International Conference at Leiden University on…

Leiden Professor of Translational Rheumatology Hans Ulrich Scherer has one foot in the clinic, where he helps patients, and the other in the lab, where he supervises researchers. He bridges these two worlds in his hunt for autoimmune rheumatic diseases.

The discovery of a new Mersenne prime was discussed on national TV by Hendrik Lenstra and Bas Jansen, who defended his thesis on Mersenne Primes in december, and by Ionica Smeets.

Sensational, is how Leiden Egyptologist Olaf Kaper described the discovery of two new chambers in the tomb of pharaoh Tutankhamun. He hopes that a second set of scans will confirm their presence unequivocally.

Nanodiscs are small, disc-shaped structures designed to mimic biological cell membranes, composed of a lipid bilayer stabilized by scaffold proteins. Membrane proteins play crucial roles in essential processes such as nutrient and waste transport, molecular recognition, and cell signalling, making them…

The Phantom of the Ego is the first comparative study that shows how the modernist account of the unconscious anticipates contemporary discoveries about the importance of mimesis in the formation of subjectivity.

Lecture

Conference

On the 11th of June, Umberto Selva successfully defended his doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Umberto on this great result.

Promotor: M. Ubbink, Co-promotor: G. Siegal

This is an Erasmus+ International Credit Mobility project of Leiden University’s Faculty of Science with University of California.

This project studies travel writing about the Dutch East Indies written between 1800 and the end of the Second World War. By analyzing both Dutch travel texts and Indigenous travel texts in Javanese and Malay, it presents a new, double-voiced perspective on (the historiography of) the Dutch colonial…

Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: Dr. L.H. Heitman

The mission in this division, headed by Laura Heitman, is to design and synthesize novel and better ligands for drug targets. Drug discovery is a lengthy but inspiring adventure. It is often an interplay between academic institutes and pharmaceutical industry, in which scientists at university develop…

If you would want to set up an alumni network after you graduated in Leiden and returned to your home country, how would you go about it? Seven Leiden alumni in China did not hesitate and decided to just do it! Last year they launched the Leiden Alumni Chapter in China, an initiative which was met with…

Physicist Joost Frenken was interviewed on the radio show 'Langs de Lijn en Omstreken' (Radio 1) about the recent discovery of superconductive graphene. The one-atom-thick material was already known for its strength, flexibility, lightweight and good conductivity.

Annelien Zweemer was awarded three poster prizes for her poster ‘Discovery of an intracellular binding site for small molecule antagonists at the chemokine receptor CCR2’.

At Molecular Physiology we teach the following courses within the Leiden Institute of Chemistry's Chemistry and Life Science and Technology programmes.

Lecture

The Nobel Prize in Physics 2016 goes to David Thouless, Michael Kosterlitz and Duncan Haldane for theoretical discoveries in the field of topological materials. Haldane spent part of 2008 in Leiden; he is the 14th Lorentz Professor to win a Nobel Prize.

Knowledge is everywhere at Leiden University. It is also accessible for those who do not study or work at the University.