The thesis describes experimental steps towards reduction of friction on the macroscopic scale by scenarios of thermo- and superlubricity well-known on the nanoscale.

The GMP Facility facilitates development and production of Advanced Therapy Medicinal Products (ATMPs) and chemical (peptide) synthesis.

To improve treatment of breast cancer patients it is important to understand all stages of breast cancer from initiation to in situ disease and progression to invasive disease. In this thesis we use intraductal injections of patient derived tissue to model ductal carcinoma in situ and invasive breast…

Tuberculosis causes 1.5 million deaths yearly and anti-tuberculosis therapies are threatened by emergence of drug resistance. Development of innovative drug combinations should be accelerated with the use of translational pharmacological models. Moreover, host-directed therapies (HDT), which stimulate…

The Physics and Quantum Matter and Optics specialisation is one of the two programmes Leiden offers in experimental physics. The programme can be tailored to individual needs and interests.

The Quantitative Pharmacology group headed by Coen van Hasselt focusses on the application of state-of-the-art quantitative pharmacometrics and systems pharmacology modeling combined with translational experimental models to develop personalized treatment strategies for antibiotics and to combat antimicrobial…

This thesis consists of two subjects, that are both a consequence of radiation pressure.

Political scientist Luzia Helfer (Leiden University) empirically tested claims about media-politics relatiopns using unique data from experimental studies with elected politicians and political journalists in Switzerland and the Netherlands.

Mechanical interactions between cells and their environment play an important role in many biological processes.

The interest of this thesis lies in spin transport in normal metals and superconducting half-metallic junctions.

The drug discovery pipeline is used to describe the stages in drug discovery. The earliest stage concerns with the identification of potential targets and molecules ('hits') that can modulate their function, while more advanced stages are about developing these hits into viable experimental drugs and…

The probability for dissociation of molecules on metal surfaces, which often controls the rate of industrially important catalytic processes, can depend strongly on how energy is partitioned in the incident molecule. There are many example systems where the addition of vibrational energy promotes reaction…

This thesis is an experimental study of the UV irradiation of the interstellar ice analogues, relevant for the different stages of the star and planet formation sequence.

In this thesis we use Josephson and noise scanning tunneling microscopy for the study of conventional, unconventional (iron-based) and disordered superconductors. On the one hand, Josephson scanning tunneling microscopy allows us to directly visualize the superfluid density with high spatial resolut…

Promotor: Prof.dr. M. de Jong, Co-Promotor: Dr. A.J. Heijboer

We study the dynamics of individual emitters in micro cavities.

Ecotox is a stimulating top-facility that provides an integrative research environment around the topic of ecotoxicological testing and experimental research. Research focus: Dose-response modelling Mode-of-actions and mechanism-of-actions Test method development, in view of targets in AOPs (adverse…

The emergence of complex diseases resulting from abnormal cell-cell signaling and the spread of infectious diseases caused by pathogens are significant threats to humanity. Unraveling the dynamic mechanisms underlying cell-cell signaling and infectious disease spreading is crucial for effective disease…

Research in the BioTherapeutics research programme is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.

In this thesis, we have used numerical approaches to study the effects of translational symmetry breaking on strange metallic systems as realised by the holographic duality⁠.

The study of tax law covers the tax system in its full width. It includes domestic, international and European tax law.

CrO2, a half-metal ferromagnet, has shown great promise for superconducting spintronics applications for nearly two decades.

This thesis explores interfacial conductance and electric field-effects in LaAlO3/SrTiO3 heterostructures.

Considering Mesoamerican Precolonial books as material objects

Can wear traces or amount of abrasion preserved on archaeological threshold and paving stones be used to reconstruct the intensity, duration, and character of ancient pedestrian and vehicular traffic?

Death, fire and identity in North-West Europe

How can the combination of sound composition, astrochemistry, and epistemological analysis provide new and unexpected insights into interstellar chemical reactivity?

Our group explores the larger domain of quantum measurement. In particular we investigate two themes that are closely connected: The detection of specially prepared quantum states of light and understanding and characterizing quantum photon detectors.

To what extent and in what manner can experimental video be used to reclaim the capacity for telling one’s own story, on one's own terms, speaking in tongues outside the linguistic framework of immune system discourse?

The CIGR comprises research groups from the Leiden Institute of Chemistry (LIC), the Leiden Academic Centre for Drug Research (LACDR) and the Leiden Institue of Physics (LION).

How does stress affect different components of behavioral impulsivity and aggression in patients with Borderline Personality Disorder compared to clinical controls (patients with Attention Deficit Hyperactivity Disorder) and healthy controls?

Practical information about the physics summer school of Leiden University: the frontiers of modern physics. This page contains information about the cost and price of the summer school, the available scholarships, location, housing and the programme. This summer school is a part of the Leiden Insitute…

The main focus of our research programme is on adolescence, a key transitional period in human development. The programme puts emphasis on combined experimental behavioural and neural analysis of normative transitions and deviations in adolescent development.

This film will be screened on Sunday, 17 May 2026 at 7:00 pm.

This is an Erasmus+ International Credit Mobility project of Leiden University’s Faculty of Science with University of California.

In the one-year Linguistics specialisation programme you will be able to focus on a specific thematic route, reflecting the linguistics expertise present at Leiden University.

Because the last Elfstedentocht celebrates its twentieth anniversary, New Scientist spoke with physics professor Tjerk Oosterkamp about his research on the slipperiness of ice and his passion for skating on natural ice.

The project Advancing The European Multilingual Experience (AThEME) studied multilingualism in Europe by incorporating and combining linguistic, cognitive and sociological perspectives.

This thesis focuses on data found in the field of computational drug discovery. New insight can be obtained by applying machine learning in various ways and in a variety of domains. Two studies delved into the application of proteochemometrics (PCM), a machine learning technique that can be used to…

The Royal Academy of Art and the Royal Conservatoire together with the Academy of Creative and Performing Arts (ACPA) at Leiden University are developing a new platform for research in and with the arts, with an emphasis on collaboration.

Promotor: Prof.dr. E.J.J. Groenen

As an alternative to the diving board shaped force sensor, we are now developing a magnetically levitated small superconducting particle – or ‘Lead Zeppelin'' – as our mechanical resonator. We explore routes towards detection of gravity between small objects.

This book brings together phonologists working in different areas to explore key questions relating to phonological primitives, the basic building blocks that are at the heart of phonological structure and over which phonological computations are carried out.

In this Thesis, novel charge induction mechanisms of ionic liquids are treated, tested and experimented on complex oxides, in particular cuprates.

Promotor: M. Ubbink, Co-promotor: G. Siegal

In this thesis we study quantum transport phenomena on the nanometer scale, in two classes of materials: topological insulators with induced superconductivity and graphene superlattices.

The ultimate aim of the project is to find out whether there are such things as

Phonology is the study of speech sounds within and across languages. It touches topics such as speech sound variation, speech sound combinations and acquisition.

The application of nanomaterials in industrial processes and consumer products provides many societal benefits, but can also lead to the release of nanomaterials into the environment. The work in this dissertation aims to provide insights into the potential environmental impacts that may follow from…