In this project, we aim to obtain a quantitative understanding of the role of the immune system in tumor regression, of the role of tumor cell heterogeneity in cancer growth and of tumor cell migration properties.

PURPOSE: To determine the effect of elasticity on the skin permeation of ketoprofen from surfactant-based vesicular formulations and elastic liposomes.

Previous research has found important inter-individual differences in the pharmacokinetics (PK) of morphine in special populations such as children, the morbidly obese or the critically ill.

On 11 November 2021, Mariana Gkliati defended the thesis 'Systemic Accountability of the European Border and Coast Guard'. The doctoral research was supervised by Prof. P. Rodrigues and Prof. L. Besselink (UvA).

This thesis presents insights from our study of various correlated electron systems with a scanning tunneling microscope (STM). In ordinary metals, electron-electron interactions exist, but get substantially screened due to the sheer number of electrons.

This thesis deals with the use of sound in interactions in the context of participatory systems and data sonification. We investigate an interactive environment where participants perceive information of the data through sound elements.

This thesis describes the synthesis and biological evaluation of TLR2/6, TLR4, TLR7/8 and TLR9 ligands, of which the activity can be conditionally controlled.

Molecular complexes can be used as electrocatalysts for oxygen reduction, water oxidation, and/or hydrogen peroxide production.

New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.

FAIRDOM consortium is an open initiative of various partners including funding programmes, large-consortia, institutes, small groups as well as individuals.

This thesis examines silicon pore optics (SPO), a technology that exploits silicon wafers from the semiconductor industry to create extremely high quality X-ray optics, by studying its manufacturing process, applications, and prospects.

PhD defence

The Educational Sciences programme group of the Institute of Education and Child Studies at Leiden University provides courses in the field of student education and the learning and development of children in the school context.

CML report 192

To what extent are individuals socialised with heteronormativity and gender norms by the national context in which they live, by Dutch schoolbooks, and within Dutch families?

When foreign matter enters our body, our immune system has to make a choice whether or not to go on the attack. There are times when the system goes wrong, and we end up with an illness or an allergic reaction. Researchers at LUMC are trying to steer the immune system. The dossier on Immunity, Infection…

In this paper, Sarah Giest and Bram Klievink highlight the effects of AI implementation on public sector innovation. This is explored by asking how AI-driven technologies in public decision-making in different organizational contexts impacts innovation in the role definition of bureaucrats.

Heloisa’s doctoral research examines classical music performance from a curatorial perspective, reflecting upon and challenging the traditional configuration of performance environments.

Promotors: Prof.dr. G.R. de Snoo, Prof.dr. G.A. Persoon, Prof.dr.ir. H.H. de Iongh

This study has been carried out in the community of Sukamiskin, a kelurahan (‘village’) in Bandung, the Capital of West Java Province, located in the Sunda Region of Indonesia.

The authors systematically search and review relevant definitions of Security by Design (SbD) in comparison with Privacy by Design (PbD).

This doctoral dissertation explores classical music performance from a curatorial perspective, reflecting upon and challenging the traditional configuration of performance environments.

The project examines the political conflict in the Red River Valley of Louisiana between the majority-black Republican Party and the overwhelmingly white Democratic Party by studying the composition and actions of each party.

Historiography of science is in its current self-image a non-evaluative discipline. Its main goal is to understand past processes of knowledge formation on their own terms. In the last few decades this approach has greatly improved our understanding of the phenomenon of science. Yet, something strange…

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Promotor: Prof.dr. E. Smets, Dr. M. Stech

Ancient historians have long been aware that patterns of coin circulation can shed light on levels of economic integration in the Roman Empire. More than forty years ago, Hopkins argued that large amounts of tax money were spent in the frontier provinces and that the non-military provinces recouped…

The immune system plays an important role in the development of atherosclerosis, the underlying cause of cardiovascular diseases. Thomas van der Heijden has discovered that immunosuppressants may play a preventative role. PhD defence 19 December.

What can continuity and change in the manufacturing of locally made ceramics from the early colonials Spanish towns of Concepción de la Vega, Cotuí and Nueva Cádiz (1492-1600) tell us about the choices people made in ceramic production as a reaction the the changing social environment?

Researchers are pulled in various, sometimes contradictory directions by the multiplication of performance metrics and new incentives to align with societal needs. Management structures, funding systems, and publication practices are increasingly influenced by pressures to promote only the highest quality…

In February 2014, the Swiss voting population accepted a constitutional initiative that aims at limiting migration through quota and, in the field of employment, national preference.

Morality, mathematics, geometry, geography, music, navigation, and language are traditionally viewed as uniquely human cultural achievements and abilities. The study of their development and variation is classified as part of the humanities and social sciences. These fields have been mainly studied…

Analysing the ways in which immigration structurally challenges and changes the organization and conceptual boundaries of national welfare states.

There was a brief disruption with our HRM system; this issue has been resolved.

At this moment, we are experiencing issues with the book lending system. Our administrators are actively investigating the problem.

On May 20th, Joost de Moor took part in a panel that examined what is (not) unique about the recent waves of climate mobilization, as well as the question of engagement with or opposition to formal global sustainability governance institutions.

On 25 January 2018, at 16:15 hrs, Yannick van den Brink will defend his doctoral thesis titled ‘Voorlopige hechtenis in het Nederlands jeugdstrafrecht’ (‘Pre-trial detention in the Dutch juvenile justice system’) at the Academy Building of Leiden University. The doctoral research is supervised by Professor…

Utilizing the polymeric platform of polypept(o)ides, this thesis describes synthesis and investigation of novel triblock copolymers to obtain carrier systems with multiple compartments for efficient siRNA delivery. Although the individual microstructure of nanoparticles differs depending on the polymeric…

Promotores: T. Hankemeier; R. Berger, Co-promotor: R.J. Vreeken