Pancreatic ductal adenocarcinoma (PDAC) is the deadliest common cancer, with only 8% of patients surviving for five years. One reason for this poor outcome is that current chemotherapy treatments are highly toxic, often leaving patients too sick to receive treatment or forcing doctors to lower the dose…

Helping cancer patients with treatment choices.

Over a thousand researchers and students protested in Leiden on 2 September against the plans to transfer money to science and technology at the expense of other disciplines. Just metres away, Minister of Education, Culture and Science, Ingrid van Engelshoven, was giving a speech at the opening of the…

Future users of the Aleida Nijland building were recently the first to have the opportunity to admire the design plan for the new building. During a user meeting, architectural firm De Zwarte Hond presented the design, and future users of the building were able to share their wishes and ideas for further…

Digitalisation can make a huge contribution to a greener future, but it must also be as sustainable as possible. To make significant progress, more collaboration and national leadership will be needed. Leiden University has therefore signed the Digital Sustainability Manifesto, which was presented on…

PhD defence

PhD defence

PhD defence

In this project, we aim to obtain a quantitative understanding of the role of the immune system in tumor regression, of the role of tumor cell heterogeneity in cancer growth and of tumor cell migration properties.

Molecular Physiology is a research group at the Leiden Institute of Chemistry dedicated to the design, synthesis and application of chemical tools to study important biological and biomedical questions. The group is headed by Prof. Dr. Mario van der Stelt and includes the research lines of Assistant…

Our research in the area of safety sciences aims to increase the mechanistic understanding of cellular toxicity of drugs and, in a broader sense, chemicals.

Leiden University has designed a new Urban Development Plan for the Humanities Campus. This plan incorporates participation from the immediate environment (neighbours and nearby residents). The plan will be available for viewing at the Leiden city council offices from 22 December for six weeks.

Cell adhesion signaling

Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.

Glycosidases (GHs) are enzymes responsible for the degradation of carbohydrates and play many roles in human health and pathophysiology. Often, abnormal levels of glycosidase activity are markedly linked to human pathologies.

Overkleeft

Animal Sciences’ contributions to the Development & Disease research theme include the mechanisms and evolution of embryonic development, the development of cognitive mechanisms, and animal models for understanding mechanisms of human disease.

Animal Sciences’ contribution to the Bioactive Molecules research theme includes research on molecules from natural sources, such as plants, insects, and snake venom, with the aim to identify novel anti-cancer, anti-inflammatory, anti-microbial, and anti-diabetic agents.

Promotor: T. Schmidt, Co-Promotor: B.E. Snaar-Jagalska

Source: Nature Biotechnology, Volume 2014, Issue June (2014)

Promotores: B. van de Water; P. Hogendoorn; J. Bovée Co-Promotor: E.H.J. Danen

Lecture, Tuesday Talks: Science Insights

PhD defence

On Monday 28 September, the University Council (UR) will discuss the Development Strategy and the Implementation Plan for Leiden University's Campus The Hague 2020-2030. The plan will then be put on the agenda of the meeting of the UR with the Executive Board on 12 October. After this, the plans for…

Het strategisch plan van de faculteit wiskunde en natuurwetenschappen (FWN) werd gepresenteerd tijdens de opening van het academisch jaar 2023-2024.

The action plan focuses on addressing key challenges posed by technological developments and trends in biomedical practices

The interdisciplinary Kiem project ‘Violence as a Population Health Problem’ has resulted in a plan to apply for a large, yet-to-be-decided research grant. The so-called pressure cooker session at the heart of the project proved very effective.

Metal-containing molecules combine geometrical features and a reactivity that are inherently different from that of organic molecules. My research focuses on light-activatable metal-based anticancer drugs and metal-functionalized liposomes. Light is a very selective way to activate photosensitive drugs…

On September 1st, Ingrid van Engelshoven, Minister of Education, Culture and Science, will present the National Action Plan Diversity and Inclusion in Education and Research. The presentation will be held at Leiden University, Campus The Hague.

‘It truly is a plan by and for us all,’ said Annetje Ottow, President of the Executive Board, at the Dies Natalis celebration on 8 February. Leiden Law School was also actively involved developing in the strategic plan.

Promotor: E. Bouwman, Co-promotor: S. Bonnet

New or improved treatments for chronic and acute illness.

The mission in this division, headed by Laura Heitman, is to design and synthesize novel and better ligands for drug targets. Drug discovery is a lengthy but inspiring adventure. It is often an interplay between academic institutes and pharmaceutical industry, in which scientists at university develop…

Improving health, enhancing well-being and reducing health disparities across society.

The majority (80%) of e-waste generated globally are recycled informally in developing countries.

Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt

PhD defence

PhD defence

PhD defence

‘Walking around in a new environment activates our brain’s learning centre. This allows us to learn better, even once we’ve returned to a familiar environment.’ This is the conclusion drawn by neuroscientist Judith Schomaker in her recent publication in Neurobiology of Learning and Memory.

On 19 July 2021, Nathan de Arriba-Sellier published an op-ed in Le Monde regarding the integration of climate change in the new monetary policy strategy of the European Central Bank (ECB).

An overview of the research at the Biologics Formulation group

By carrying out fundamental research and providing excellent education, universities become a breeding ground for innovation and entrepreneurship.

To get a feeling of how we operate at LED3 when it comes to Early Drug Discovery, please browse through our case studies. When you select a case study you’ll find relevant contacts.

The Leiden University Medical Center (LUMC) is committed to improving healthcare and the health of individuals. The LUMC staff put this mission into practice on a daily basis with their leading research, cutting-edge teaching and optimal, innovative healthcare.

A consortium of research groups, including that of LACDR professor Erik Danen, will use an NWO Perspective grant of nearly five million euros to build a universal standard for organ-on-chip models. They aim to stimulate the application of these chips in the biomedical and pharmaceutical industry. Danen…

Anne Aagten comments on new European plans to deal with migration in podcast on news site nu.nl