Which genes are involved in woodiness and associated traits such as drought tolerance, flowering time, stem elongation, life span, and plant herbivory, and how do these gene regulatory pathways overlap?

In this research group, led by Dr. Joost Beltman, the aim is to employ mathematical and computational dynamical modelling approaches in order to quantitatively and mechanistically understand the dynamical behaviour and regulation of intracellular networks of genes, proteins and metabolites as well as…

Bones hold a wealth of information about a person’s life, revealing details about where they came from, how old they were when they died and what diseases they may have had. Scientists can use this data to piece together aspects of an individual's life, offering valuable insights that can help address…

Knowledge is everywhere at Leiden University. It is also accessible for those who do not study or work at the University.

Lecture

Meet the scientists within the LED3 community

On this page you can find information about previous CCLS events.

Observations made with the ALMA telescope in Chile and ESA’s Rosetta mission, have detected the faint molecular fingerprint of methyl chloride in gas, a chemical commonly produced by industrial biological processes on Earth, around both an infant star and a comet. Methyl chloride, also known as Freon-40,…

Tackling key challenges of Chemical Biology and Medicinal Chemistry to aid drug discovery is one of the focus areas of Leiden University. To this end, the Leiden Early Drug Discovery & Development network (LED3) was established by the Leiden Institute of Chemistry (LIC), the Institute of Biology Leiden…

Antibiotic-resistant bacteria pose a major health threat. Addressing this challenge requires among others the development of new antibacterial compounds. The research described in this thesis focuses on discovering novel antibiotics from soil bacteria, specifically Streptomyces and Paenibacillus.Despite…

Steffen Brünle's group investigates G protein-coupled receptors (GPCRs). These essential membrane proteins are prime targets for therapeutic drug development in disease and cancer treatment.

Metastasis is responsible for over 90% of cancer-related deaths and arises from the ability of a small subset of tumor cells to detach from the primary tumor, overcome multiple biochemical and mechanical barriers, disseminate through the body, and colonize distant organs.

On Friday, 29 October 2021 (15.15-17.00), this year’s lecture will be delivered by Prof. Howard Louthan, (University of Minnesota, Minneapolis, USA) at the Faculty Club of Leiden University. It will be titled ‘Revisiting a Renaissance Classic: Theuerdank, Maximilian I (1486-1519) and the Discovery of…

Milan Allan has received the Bryan R. Coles Prize at the International Conference on Strongly Correlated Electron Systems (SCES) in Prague.

With Leiden2022 drawing nearer, LeidenGlobal is busy developing extra activities to demonstrate the knowledge that is present in Leiden and to create interaction with a wider audience. With this valorisation, the partnership between several cultural and academic institutions in Leiden matches the theme…

This COIn Grant 2025 awarded project allows Leiden University researchers and students to do research on the world’s largest corpus of digitized Ottoman language periodicals and books.

Real-life processes are characterized by dynamics involving time. Examples are walking, sleeping, disease progress in medical treatment, and events in a workflow.

The Leiden Academic Centre for Drug Research (LACDR) is a centre of excellence for multidisciplinary research on drug discovery and development.

In this research group, headed by Laura Heitman, novel receptor concepts in drug discovery are studied, aiming to increase the effectivity of medicines. Many drugs act via so-called G protein-coupled receptors (GPCRs) and therefore our research is mainly focused on understanding and improving drug-receptor…

Researchers at LED3 are working together with biopharmaceutical company Galapagos to develop software for use in early drug discovery (funded by NWO). This software is able to design molecules with several simultaneously optimized characteristics and will also take prediction reliability into consideration…

In CCLS several subgroups have formed, below you can find an overview of these groups with the names of the leading researchers and a short outline of the project.

The research within the Division of Cell Systems and Drug Safety, headed by Prof. Bob van de Water, is focused on novel therapeutic modalities and novel concepts in early drug discovery, in order to develop more effective and safer therapeutic strategies. We generate advanced cell and computational…

LIACS organizes different lectures and seminars like the LCN2 Seminars and SAILS Lunch Time-seminars.

Supervisor: Maarten Doornbos

The research conducted at the Leiden Academic Centre for Drug Research is clustered within the divisions of BioTherapeutics, Cell Systems and Drug Safety, Medicinal Chemistry and Systems Pharmacology and Pharmacy, and the Metabolomics and Analytics Centre.

Providing each cancer patient with the right treatment remains a challenge. Oncode Accelerator aims to change this by innovating the way we develop cancer treatments, thus ensuring the patient is at the heart of the process. Leiden University, the LUMC and other partners will implement this new way…

YAL connects academics to society.

These are two separate Erasmus+ International Credit Mobility projects with Monash University in Australia, one of the Leiden Academic Centre for Drug Research (LACDR), the other of Leiden University’s Faculty of Law (LLS).

Living in China and want to meet other Leiden Alumni? Read about the new Leiden Alumni Chapter in China and join them on LinkedIn and the upcoming events.

Less than 1 in 10 drug candidates that enter phase 1 clinical trials actually gets approved for human use.

The Kroese-Duijsters Symposia aim to provide researchers from different fields and different career stages to meet in an informal setting, to stimulate discussions and to start new collaborations. The Kroese-Duijsters Symposia started in 2022 and we are pleased to invite you to the 4th Kroese-Duijsters…

Over several decades, a variety of computational methods for drug discovery have been proposed and applied in practice. With the accumulation of data and the development of machine learning methods, computational drug design methods have gradually shifted to a new paradigm, i.e. deep learning methods…

Peter Flach is Professor of Artificial Intelligence at the University of Bristol. An internationally leading scholar in the evaluation and improvement of machine learning models using ROC analysis and calibration, he has also published on mining highly structured data, on knowledge-driven and explainable…

Promotores: A.P. IJzerman, H.W.T. van Vlijmen

Over the past years it has been discovered that the population of extra-solar planets is large and diverse.

Research from the Living Lab is important for society. For example, scientists from the Living Lab discovered that the pesticide thiacloprid is up to 2,500 times more harmful to insects than was thought on the basis of regular lab research. Partly because of this discovery, the European Commission decided…