The research presented in this thesis concerns one of the most important questions in software engineering of our time: how can we make sure that software is free from memory safety bugs?

Identifying natural plant-associated bacteria that provide targeted inhibition of pathogens through the production of antimicrobial peptides.

Constraint multi-objective optimization with a limited budget for function evaluations is challenging. This thesis tackles this problem by proposing new optimization algorithms. These algorithms are applied on holistic ship design problems. This helps naval architects balance objectives like cost, efficiency,…

With increasing carbon dioxide levels in the atmosphere and their detrimental effect on the global climate, modern society needs to push for more renewable energy sources. Storing widely accessible and abundant solar energy in chemical bonds in the form of molecular fuel via artificial photosynthesis…

Archaeologists often use the percentages of heat-affected stone or bone artifacts found at archaeological sites as a way to determine how frequently fire was used by the inhabitants. Andrew Sorensen and Fulco Scherjon have come up with a computer model called 'fiReproxies' to simulate how fires used…

Affective Computing (AC and sometimes called ‘Emotional AI’) provides opportunities to automatically process emotional data. However, is EU data protection law fit for purpose when it is applied to such AC approaches?

Drug-target binding kinetics determine the time course of the central event in pharmacotherapy: Drug-target interaction.

Computer Science on place 51 in QS World Universities Ranking 2011

Promotor: S.J. Edixhoven, Co-promotor: K.J. Batenburg

LIACS scholars Thomas Bäck and Hao Wang will be the new Editors-in-Chief of the Evolutionary Computation Journal from November 1. Published by MIT Press since its foundation in 1993, the journal stands as a keystone in the field, providing a global platform for researchers exploring the workings of…

Designing innovative algorithms, thinking outside the box, and brainstorming over coffee with his colleagues — this is what physicist Stefano Polla enjoys most. His success shines through in his nomination for the C.J. Kok Jury Award 2024 for PhD thesis of the Year.

For the first time, a computer can compete with the very best human players in StarCraft II, a video game played by tens of thousands at a professional level and by millions just for fun. Mike Preuss, university lecturer at the Leiden Institute of Advanced Computer Science (LIACS) responds to the achievement…

Can a computer give just as good a judgment as a judge? Professor emeritus Law and IT believes it can and talks about using computers in the courtroom in a podcast of the Universiteit van Vlaanderen.

With the rise of AI, interest in computational linguistics and language models has taken flight. But machines are far from being able to go it alone. In her inaugural lecture, Professor Carole Tiberius will stress the importance of research on word combinations. ‘We know a great deal but there is a…

Promotor: S.M. Verduyn Lunel

In healthcare, gender and sex considerations are crucial because they affect individuals' health and disease differences. Yet, most algorithms deployed in the healthcare context lack close consideration of these aspects and do not account for bias detection. In their latest paper, Eduard Fosch-Villaronga,…

Despite being the object of intense study, embryonic development has been difficult to model due to a number of reasons. First, complex tissues can be comprised of many cell types, of which we probably only know a subset.

Samineh Bagheri is the first PhD candidate to defend her thesis fully remotely.

On 13 March 2024, Carlotta Rigotti, postdoc researcher at eLaw, and Alexandre Puttick, postdoc researcher at Bern University of Applied Sciences, remotely presented the working paper 'Towards mitigating diversity bias of AI in recruitment and selection via value sensitive design' at the ACM Symposium…

Promotores: J.N. Kok, H.J. Hoogeboom

Leiden Law Cast is a podcast made by Leiden Law School, Leiden University, for everyone who wants to learn more about current legal issues.

Leiden Law Cast is a podcast made by Leiden Law School, Leiden University, for everyone who wants to learn more about current legal issues.

Gianclaudio Malgieri, after having served as an Editorial Board Member of Computer Law & Security Review, Elsevier (CLSR) in the last three years, has now been appointed as Associate Editor of that review.

This thesis investigates the application of deep learning techniques in image analysis across various domains, focusing on four main themes: feature extraction, classification, segmentation, and integration, demonstrating the transformative potential of these technologies.

This thesis describes the importance of being able to control the selectivity of potential drug candidates.

Promotor: Prof.dr. E. Deprettere

This thesis is about augmented reality (AR). AR is commonly considered a technology that integrates virtual images into a user’s view of the real world.

Humans can see the world through the eyes of other humans and imagine what they know, want, and intend. This competence is known as Theory of Mind.

The first larger quantum computers will soon be available. These computers need new software. Researchers at Leiden University have been awarded a Gravitation grant to develop the necessary software. They will be collaborating with colleagues from other research institutions.

This thesis focuses on two processes involved in fighting infections: metabolism and immune cell motility and navigation.

This thesis focuses on data found in the field of computational drug discovery. New insight can be obtained by applying machine learning in various ways and in a variety of domains. Two studies delved into the application of proteochemometrics (PCM), a machine learning technique that can be used to…

The Collective Experience of Empathic Data Systems (CEEDs) consortium developed novel integrated technologies that support experiencing, analysing and understanding of very large datasets.

A complex community of microbes develops in the infant gut shortly after birth. We call this community the infant gut microbiota. The microbiota influences the health of the infant, which makes the composition and function of the infant gut microbiota an important topic to study.

The aim of the research presented in this thesis was to develop new methods forchallenging systems in liquid-state NMR using paramagnetic effects generated by thetwo-armed probe CLaNP-5.

How do public organizations use strategic regulatory communication in regulatory governance?

An assessment approach that tailors to children’s instructional needs

State secretary Mona Keijzer received the National Agenda on Quantum Technology from Robbert Dijkgraaf on 16 September. With this agenda, Dutch knowledge institutes and high-tech companies identify what is needed to maintain and strengthen the Dutch pioneering role in this area. Researchers from Leiden…

Simon Portegies Zwart, professor of Computational Astrophysics, uses computers to simulate the evolution of stars. We speak with him about his field and about the challenges of working with huge amounts of complex data.