2,129 search results for “shared cell differentiatie” in the Public website
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Roos VlaskampAdministrative Shared Service Centre
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Arjan van RijnAdministrative Shared Service Centre
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Paddy Splinter-van KleefAdministrative Shared Service Centre
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Kitty BlomAdministrative Shared Service Centre
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Karin van KlaverenAdministrative Shared Service Centre
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Remko OffringaFaculty of Science
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Gold nanoparticle-peptide conjugates for biomedical applications
Despite the fact that gold nanoparticles (GNPs) are one of the most studied nanoparticles, there is still a necessity for new approaches allowing for effective protective coating to enable wider use of GNPs in biomedical applications.
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Vidi Grant for Stefan Semrau: how does bioelectricity shape embryonic development?
Leiden biophysicist Stefan Semrau was granted an NWO Vidi earlier this month. He will use the grant to study the role of electricity in embryonic development and tissue regeneration.
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Bob van de WaterFaculty of Science
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Cellular Forces: Adhering, Shaping, Sensing and Dividing
Promotor: Prof.dr. T. Schmidt
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Breaking the Unbreakable: Computational and Biochemical Identification of Polyethylene-Degrading Enzymes
Engineering an efficient microbial enzymatic polyethylene degradation pathway via an innovative combination of biochemistry and computational biology tools for enzyme discovery and characterization.
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Alireza Mashaghi TabariFaculty of Science
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Regenerative medicine
Repairing organs, tissues and cells to fight chronic diseases.
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Cardiovascular Pharmacology
The Cardiovascular Pharmacology research group headed by Ilze Bot aims to elucidate the mechanisms that underlie atherosclerotic plaque destabilization, which is the key process that leads to acute cardiovascular syndromes such as a myocardial infarction or stroke.
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Research
An overview of the research at the Cancer Dug Target Discovery group.
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Vascular and Regenerative Medicine
Methods of treatment for chronic illnesses are limited. Doctors and researchers at Leiden University Medical Center (LUMC) and Leiden University are working on new therapies as an alternative for organ transplants. The goal is to cure the illnesses by restoring organs to their original function. Stem…
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Therapeutic intervention to enhance atherosclerotic plaque stability-projects
For more information regarding ongoing research projects, please contact Dr. Ilze Bot.
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Development & Disease in Microbial Sciences
Microbial Sciences'contribution to the Development & Disease research theme is to perform world-class research to understand cellular morphogenesis, growth, development and virulence of microbes.
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Cancer Drug Target Discovery
In this research group, headed by Prof. Erik Danen, the aim is to unravel cellular signaling mechanisms in normal and diseased cells, with a long-standing interest in cell adhesion signaling. In complex multicellular organisms such as ourselves, a division of labor emerges where different tissues and…
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Cancer Therapeutics and Drug Safety
In this research group, headed by Bob Van de Water, cell signaling programs that underlie adverse drug reactions as well as cancer development and progression are unraveled. Adverse drug reactions involve cell injury in critical target organ cells which leads to the activation of cellular stress response…
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Immunotherapy to limit atherosclerosis
Atherosclerosis is a chronic inflammatory disease, and vaccination may be an attractive method to induce long lasting protection against endogenous factors that contribute to the development of atherosclerosis. We have shown that for example vaccination against modified LDL or interleukin-12 limits…
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Cancer Drug Target Discovery
We focus on a better understanding of the mechanisms of cancer drug resistance and metastasis.
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Blood vessels on a chip make the cause of dementia visible
New technology offers many new possibilities for research, such as on dementia. ‘Organ-on-a-chip’ is a new technology in which small bits of organ are grown out of stem cells on a small plastic plate. A small piece of blood vessel, heart or nerve offers many new possibilities for research, such as…
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RNA splicing in breast cancer progression
In this thesis, we aimed to better understand the underlying mechanisms involved in TNBC progression and metastasis formation and discover new targets to reduce breast cancer related deaths.
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Protease-Responsive Targeted Delivery of Chemotherapeutics Holds Great Promise for the Treatment of Pancreatic Ductal Adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is the deadliest common cancer, with only 8% of patients surviving for five years. One reason for this poor outcome is that current chemotherapy treatments are highly toxic, often leaving patients too sick to receive treatment or forcing doctors to lower the dose…
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Targeted Therapy for Triple-Negative Breast Cancer
The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.
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Immune Activation and Tolerance
The Immune Activation and Tolerance group is headed by Dr. Bram Slütter. Vaccination is an experimental, but promising, treatment strategy for atherosclerosis. Previous work has shown that immunization of mice with modified LDL particles can reduce atherosclerotic lesion development, however such vaccines…
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Computational modeling of tumor growth and metastasis and the role of the immune system in tumor destruction
In this project, we aim to obtain a quantitative understanding of the role of the immune system in tumor regression, of the role of tumor cell heterogeneity in cancer growth and of tumor cell migration properties.
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Marcel DiddenISSC
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Saidi NiyonkuruISSC
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Juriaan GroenenAdministrative Shared Service Centre
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Sabine SpreeuwAdministrative Shared Service Centre
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Ruud SchouwenaarAdministrative Shared Service Centre
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Rick SlotboomAdministrative Shared Service Centre
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Eelco VromenAdministrative Shared Service Centre
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Jasper AlsemaAdministrative Shared Service Centre
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Nick VeltAdministrative Shared Service Centre
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Simone BettonvilAdministrative Shared Service Centre
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Esther MaesAdministrative Shared Service Centre
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Nathalie BrinkAdministrative Shared Service Centre
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Nori PoppeliersAdministrative Shared Service Centre
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Tran VoAdministrative Shared Service Centre
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Justine HetterschijAdministrative Shared Service Centre
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Henco ParlevlietAdministrative Shared Service Centre
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Lisa OtterbeekAdministrative Shared Service Centre
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Petra ScheepersAdministrative Shared Service Centre
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Erik WeenkAdministrative Shared Service Centre
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Dita SulbaránAdministrative Shared Service Centre
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Stefan PlanjerISSC
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Ab HelversteijnISSC