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1,615 search results for “shared cell differentiatie” in the Public website

• Chara Plant BioDynamics Laboratory

  The Green algae Chara as model system for intra and inter cellular transport processes.

• Programme structure Transfusion Medicine and Cellular and Tissue Therapies (MSc)

  Courses cover a broad range of relevant subjects and provide in-depth theoretical knowledge as well as training in practical skills and advanced research tools.

• Structure and regulation in photosynthesis Research project

  Plants, algae and cyanobacteria have the amazing capacity to perform delicate photophysical and photochemical processes of light capture, excitation transfer, charge separation and catalysis in fluctuating living environments. As a consequence, photosynthetic proteins and membranes form dynamic architectures.…

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  Ronald Walthaus Head of Department Customer Applications Services

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  Sandra Brautigam Functional application manager

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  Ezra Dijkstra Helpdesk Staff Member

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  Debby Venema-Bruinsma Head of Service Point & Business Support Office

  Administrative Shared Service Centre

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  Annemieke Monster-Beijersbergen Functional application manager HRM

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  Rowena van der Reijden Staff member HR Administration

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  Frank Gubbels BI & Data Engineer

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  Edith den Boer Coordinator HR Administration

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  Auke Visser Business Analyst

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  Angélique van der Leeuw Proces Coordinator

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  Leonora van Hemert Staff member Servicedesk HR

  Administrative Shared Service Centre

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  Mark van Leeuwen Department Manager Customer Relations

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  Chi Leung Wong Senior IAM Application Manager

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  Erwin van Lingen IAM Application Manager (guest)

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  Wim van den Berg Coordinator ICT Sales

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  Thijs Buurman Functional Application Manager

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  Julian van der Kraats Product Owner

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  Noeky Karreman Project manager

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  Loek ter Laak Network Administrator

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  Trudi Blomsma-Peters Management assistent / department secretary

  Administration and Central Services

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  Paul van der Elst Senior Engineer Integration

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  Arjan Zuidhof SOC Security Specialist

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  Mohamed Boumhand SharePoint Technical Specialist

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• Centre for Interdisciplinary Genome Research

  The CIGR brings together a diverse range of unique expertise in genome research rooted in biology, chemistry and physics. Members of the CIGR investigate genome folding and genome transactions. An important aspect is direct as well as long term relevance for medicine.

• Kinetic profiling of positive allosteric modulators of the mGlu2 receptor Research project

  Supervisor: Maarten Doornbos

• Molecular Signatures of the Evolving Immune Response in Mice following a Bordetella pertussis Infection Research output

  Worldwide resurgence of pertussis necessitates the need for improvement of pertussis vaccines and vaccination strategies.

• Liposome-based vaccines for immune modulation: from antigen selection to nanoparticle design Research output

  Nanoparticles can be used as delivery systems for both small molecules and macromolecules such as proteins, peptides or oligonucleotides. This thesis focuses on the use of liposomes, nanometric vesicles formed by a lipid bilayer enclosing an aqueous core. Liposomes are highly versatile delivery syst…

• Infrastructure Systems Pharmacology and Pharmacy

  An overview of our infrastructure at the SPP division:

• Collaborative and effective drug development Research Dossier

  There are many complex links in the chain that provides patients with new drugs: from fundamental science, to clinical tests, to production. The entire chain can be found in Leiden. Leiden University, the Leiden University Medical Center (LUMC) and the businesses at the Leiden Bio Science Park (LBSP)…

• Leiden researchers discover genes that affect spread of breast cancer News - 18 March 2015

  Researchers at Leiden University have mapped genes that cause breast cancer cells to migrate. The Leiden toxicologists Professor Bob van de Water, Dr Wies van Roosmalen, Dr Sylvia E. Le Dévédec and colleagues studied 1500 individual genes. They found eight, including the SRPK1 gene, that regulate the…

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  Daphny Ulje-Kouer Management assistant

  Administrative Shared Service Centre

• R-ELEVATION Research project

  How do plant defense genes get activated?

• Development of a Kidney-on-a-Chip Model for Compound Screening and Transport Studies Research output

  Pharmaceutical companies, governments and the general public have become increasingly aware that animal models used in drug testing lack vital aspects to serve as an accurate representation of human biology. As models of the human body should become more physiologically relevant, animal models no longer…

• Getting personal: Advancing personalized oncology through computational analysis of membrane proteins Research output

  Cancer is considered the silent pandemic of the 21st century and the second leading cause of death worldwide.

• In vitro and in vivo delivery of functionalized nanoparticles via coiled-coil interactions Research output

  Promotor: A. Kros, Co-promotor: R.R.C.L. Olsthoorn

• Developmental effects of polystyrene nanoparticles in the chicken embryo Research output

  There is concern about the threat that nanoplastics (NPs) may pose to both wildlife and humans. This thesis explores the mechanisms of toxicity of polystyrene nanoparticles (PS-NPs) in chicken embryo.

• Collaborations Ecotox

  Ecotox is located in an ambitious surrounding at the Leiden University. It is an initiative of both institutes Institute of Environmental Sciences (CML) and Institute of Biology Leiden (IBL).

• Systems vaccinology: molecular signatures of immunity to Bordetella pertussis Research output

  Promotor: G.F.A. Kersten, W. Jiskoot, Co-promotor: B. Metz

• Barrier properties of an N/TERT based human skin equivalent Research output

  Human skin equivalents (HSEs) can be a valuable tool to study aspects of human skin, including the skin barrier, or to perform chemical or toxicological screenings.

• Deep Learning Solutions for Domain-Specific Image Segmentation Research output

  Image segmentation is a fundamental task in computer vision, with applications ranging from medical diagnostics to archaeological research.

• Towards a mechanistic understanding of nanoparticle behavior using zebrafish Research output

  The work described in this dissertation contributes to a better mechanistic understanding of nanoparticles in vivo. To achieve that goal, we used the zebrafish as a highly predictive pre-screening model of nanoparticles.

• Synthesis of chemical tools to study the immune system Research output

  This thesis describes the synthesis and biological evaluation of TLR2/6, TLR4, TLR7/8 and TLR9 ligands, of which the activity can be conditionally controlled.