106 search results for “metabolic nanoparticles” in the Staff website
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Improving safety assessment of nanoparticles
How safe are the nanoparticles in transparent sunscreen, anti-odour socks and bacteria-resistant plasters? Although microbes are present on all organisms, the tools that estimate the safety of nanomaterials still hardly take them into account. Bregje Brinkmann explored the role of these microbes during…
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Marko RadojkovicFaculty of Science
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The effect of nanoparticles on our planet
‘Solar panels, toothpaste and sport socks. What do these things have in common?’ Martina Vijver, professor of ecotoxicology begins her TEDx-talk. Watch her online lecture if you want to learn more about the effects of nano-particles on our environment and health.
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Publication on the design of multifunctionalized nanoparticles
Despite considerable progress in the design of multifunctionalized nanoparticles (NPs) that selectively target specific cell types, their systemic application often results in unwanted liver accumulation. The exact mechanisms for this general observation are still unclear.
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Special nanoparticles for cancer therapy! Will you help?
Developing a better treatment for patients with head and neck cancer, that is what Binanox, The 2022 iGEM Leiden team, want to achieve. They hope to raise at least 10,000 euros for this cause. Support their crowdfunding campaign today.
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How drugs work better when encapsulated in nanoparticles
Chemist Tobias Bauer discovered ways to improve drugs by encapsulating them. Packages with iron nanoparticles, for example, can stimulate immune cells. Bauer will receive his PhD on 9 June.
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Alexa SchrickelSocial & Behavioural Sciences
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Camille SouamaFaculty of Social and Behavioural Sciences
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Lennart Schada von BorzyskowskiFaculty of Science
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Hans AertsFaculty of Science
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Dongdong BiFaculty of Science
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Nanoparticles: shapeshifters that pass along the food chain and end up in the brain
Nanomaterials can pass much further along the food chain than was previously thought. The particles can change shape and size in each organism, enabling them to pass on to the next one in the chain. Researchers from the Institute of Environmental Sciences discovered this accidentally when using a novel…
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Eline DekeysterFaculty of Social and Behavioural Sciences
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Leiden Scientists: 'Environmental risks of new pesticides with nanoparticles insufficiently examined'
The environmental risks of new pesticides containing nanoparticles are inadequately researched, according to four Leiden scientists in the scientific journal Environmental Science & Technology. They call for an examination of the long-term and environmental effects of pesticides containing nanoparti…
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Rik MomFaculty of Science
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Review paper on the potential impact drug-metabolizing enzymes on brain exposure
PhD candidate Mengxu Zhang (Division of Systems Pharmacology and Pharmacy) published a comprehensive and important review on “The potential impact of CYP and UGT drug-metabolizing enzymes on brain target site drug exposure” in Drug Metabolism Reviews.
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Eline Dekeyster in Podcast Metabolic Mind: Can ketogenic therapy help with autism and mental health?
Could ketogenic therapy change the future of autism spectrum disorder (ASD) treatment? Bret Scher sits down with Eline Dekeyster to explore how nutritional ketosis may support individuals with autism and other brain-based conditions.
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What makes us ill?
Genes predict whether you have a propensity for an illness but environmental factors often have the last word: nutrition, air pollution, lifestyle, stress. The exposome as both culprit and chance. Large-scale research is being carried out into this at Leiden. Thomas Hankemeier, Professor of Analytical…
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Aleksandrina SkvortsovaFaculty of Social and Behavioural Sciences
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Sandra IrmischFaculty of Science
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Miranda van EckFaculty of Science
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Leiden biologists find nanoplastics in developing heart
Nanoplastics can accumulate in developing hearts, according to a study by biologist Meiru Wang from Leiden University. Her research on chicken embryos sheds new light on how these tiny plastic particles pose a threat to our health.
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Laura de JongFaculty of Science
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Irene GrootFaculty of Science
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Targeting the immune system to inhibit atherosclerosis
A new treatment for atherosclerosis showed promising results in isolated cells but proved to be less effective in initial animal tests. Bachelor student Biopharmaceutical Sciences Willemijn van der Heijden aimed to understand why. She investigated whether the formation of a protein layer around the…
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Robert VerpoorteFaculty of Science
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Nanoparticles and Microfluidics for Future Tuberculosis Vaccines
PhD defence
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Tomer FishmanFaculty of Science
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Shiza AslamFaculty of Science
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Microglial lipid metabolism: a delicate balance
PhD defence
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Life after the Grand Jamboree: Wrapping-up iGEM
‘A challenging rollercoaster, but also a very bonding and insightful experience,’ that’s how the team of iGEM Leiden 2022 wraps up their participation in the iGEM contest. The contest for synthetic biology climaxed during the Grand Jamboree in Paris. The team ended up in the top 10 of over 360 teams…
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Chao DuFaculty of Science
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Peter van SantbrinkFaculty of Science
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Lipid nanoparticle technology for mRNA delivery: Bridging vaccine applications with fundamental insights into nano-bio interactions
PhD defence
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A chemical biology approach to explore lipid metabolism in neurological disorders
PhD defence
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Microstructural and Metabolic Alterations in the Zebrafish Brain Induced by Toll-Like Receptor 2 Deficiency
PhD defence
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Design and Synthesis of Click Lipids as Tools to Study Immune Cell Metabolism
PhD defence
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The impact of non-genetic factors on drug metabolism: towards better phenotype predictions
PhD defence
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Marc KoperFaculty of Science
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Jeroen BussmannFaculty of Science
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Can we make bioplastics with artificial photosynthesis?
Mimicking photosynthesis to produce bioplastics sustainably and efficiently. Researchers from the Institute of Biology Leiden (IBL) and the Leiden Institute of Chemistry (LIC) will assess this new approach. ‘An exciting opportunity to explore a new, appealing research topic in a collaboration between…
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Nutrition and fasting for the brain: why the Keto diet shows promise
Autism, Alzheimer’s, and bipolar disorder: can the development of these mental health conditions be influenced by the ketogenic diet? Increasingly, research suggests it might. 'For those it helps, it can be life-changing,' says neuroscientist Eline Dekeyster.
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Nature Communications paper on therapeutic melanoma inhibition by local micelle-mediated cyclic nucleotide repression
Cancer immunotherapy represents a significant breakthrough in cancer treatment. However, tumors have numerous mechanisms by which they evade destruction by the immune system. It is therefore necessary to decipher and reverse these mechanisms in order to improve immunotherapies.
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Mikolaj SzachniewiczFaculty of Science
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New easy-to-use tuberculosis vaccine patch in development
Researchers from Leiden have developed a promising TB vaccine that users can self-administer via a special patch. This could be beneficial for countries with limited health services, says PhD candidate Malene Neustrup.
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Polypeptide Therapeutic Solutions and Universiteit Leiden Announce Collaboration to Develop Advanced Polyaminoacid Drug Delivery Systems
Polypeptide Therapeutic Solutions (PTS), a leader in the design, development and custom manufacturing of polyamino-acid based delivery systems for therapeutic drugs and the Leiden Academic Centre for Drug Research (LACDR) today announced a research collaboration to develop advanced drug delivery systems…
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Driven by curiosity: master student Linde Schoenmaker publishes review paper about COVID-19 vaccine stability
During her search for a subject for the literature study of the Bio-Pharmaceutical Sciences master programme, Linde Schoenmaker read a press release about the ultra-low storage temperatures of the COVID-19 vaccines. She wondered why these vaccines must be stored at such cold conditions. Her question…
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Lianne Stevens wins The The European Journal of Pharmaceutical Sciences 2024 Best Paper Award
At the EUFEPS Meeting in Vienna, Lianne Stevens and team received the EJPS – Best Paper Award 2024.
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Malformations in heart, eyes and nervous system: Nano-plastics disrupt growth
Nano-plastics cause malformations. Meiru Wang, researcher at the Institute of Biology Leiden, looked at the extreme effects polystyrene nano-particles could have, using chicken embryos as a model. Her results were quite alarming. Especially as nano-particles are everywhere. In the air, floating through…
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Lars JeukenFaculty of Science