879 search results for “autism spectrum disorders” in the Public website
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Mood variability during adolescent development and its relation to sleep and brain development
During adolescence, mood disorder onset peaks. Mood variability is associated with negative mental health outcomes, so understanding biological factors that might be associated with mood variability, such as sleep and structural brain development, could elucidate the mechanisms underlying mood and anxiety…
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Self-regulation in boys with ODD/CD
Understanding individual differences in self-regulation in boys with ODD/CD on the level of brain, cognition and behavior
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Fluorescence Polarization Activity-Based Protein Profiling on Retaining Glycosidases
Glycosidases are important enzymes in the turnover of polysaccharides and glycoconjugates, and are involved in a range of human pathologies including genetic disorders such as Gaucher and Pompe disease, but also in various cancers.
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European Lead Factory
The European Lead Factory has been created with the ultimate goal to develop lead drug candidates to address neglected diseases including bacterial infections, psychiatric disorders and oncology.
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Systems pharmacokinetic models to the prediction of local CNS drug concentrations in human
Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.
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Some case studies of random walks in dynamic random environments
Promotor: Promotor: W.Th.F. den Hollander, Co-promotor: V. Sidoravicius.
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Clinical Neurodevelopmental Sciences Leiden University
The group Clinical Neurodevelopmental Sciences has expertise in individual differences in child development, in particular the development of psychopathology, ranging from mild to severe neurodevelopmental disorders.
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Analytical chemistry and biochemistry of glycosphingolipids: new developments and insights
Advanced mass spectrometry of glycosphingolipids takes the central stage in this thesis. Investigations focus on characterization of glycosphingolipid metabolism in health and disease with emphasis to the detection and accurate quantitation of known and so far unknown glycosphingolipids and closely…
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Noonan and LEOPARD syndrome in zebrafish: molecular mechanisms and cardiac development
Promotor: Prof.dr. J. den Hertog
- Martina Huber Lab - EPR Group
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Our Research
From basic science to real-world interventions
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Computerised Dynamic Testing
An assessment approach that tailors to children’s instructional needs
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Medical Biochemistry
Medical Biochemistry is a section of the Leiden Institute of Chemistry at Leiden University. The section is headed by Prof. Dr. Hans Aerts.
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Why Leiden University?
The Physics and Education master specialisation gives you the opportunity to combine physics research with an excellent education in becoming a physics teacher.
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Why Leiden University?
The Physics and SCS master specialisation gives you the opportunity to combine Physics research with different aspects of science communication.
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Why Leiden University?
World-class research is integral part of the master’s education. You obtain a Physics degree from an institute with an international reputation. Research in this programme is fundamental and curiosity-driven.
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Inverse design of curvature-sensing antiviral peptides
Viral diseases constitute one of the major challenges in modern medicine. Membrane-targeting have broad-spectrum potential and could distinguish viral membranes from the host cell plasma membrane by the difference in membrane curvature.
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Human skin equivalent barrier optimization
The currently available in vitro generated human skin equivalents resemble the human skin in many aspects. However, some essential barrier characteristics do not fully mimic the native barrier. Consequently, the human skin equivalents cannot be used for screening of drugs for skin penetration.
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Search for cosmic neutrinos with ANTARES
Promotor: Prof.dr. M. de Jong, Co-Promotor: Dr. A.J. Heijboer
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Programme structure
You have ample opportunities to assemble your own study path. The courses cover the full spectrum from theoretical early universe to observational cosmology.
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Control processes in children’s word productions
How does task context affect children’s word productions?
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New Methods for (f)MRI Analysis
Analysis of neuroimaging data requires multiple steps where statistics play a crucial role. The MRI methods research group develops new statistical methods that are accurate, transparent and easy to use.
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Research
How do people acquire language? How can you train your brain? What is the effect of stress on an unborn child? LIBC research topics range from language processing to cognitive robotics, and from psychiatric disorders to the impact of social factors on human behaviour. Meet several main research topics…
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Migraine@Work: work ability in employees with migraine
This study aims to answer two main research questions: (1) What are the main predictors of work ability in employees with migraine? (2) Can we optimise work ability in employees with migraine using a web-based intervention focused on these relevant predictors?
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Mosaic 2.0 scholarship for Rüya Akdağ
Rüya Akdağ is part of a research team with the aim of further studying social anxiety. The Leiden psychologist receives the grant for her doctoral research on the role of emotions and cognition in the emergence and occurrence of social anxiety in adolescents.
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Predictors, symptom dynamics and neural mechanisms of bipolar disorders
PhD defence
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Immune modulation and monitoring of cell therapy in inflammatory disorders
PhD defence
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Bone and joint disorders: Screening and early clinical drug development
PhD defence
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AI-MAPS
AI MAPS adopts a freedom and social well-being perspective and focuses on three themes to address key security challenges; Social disorder and public nuisances in neighbourhoods, High-impact crime, and Crowds and events.
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People and Projects
Our team consists of the following members.
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Evaluation and implementation of innovative diagnostics and treatment
If a new method has been developed to recognize and treat a (neuro-)psychological disorder or related behavioral factors, it cannot yet be used directly in clinical practice. First, the method should be evaluated, preferably in randomized controlled trials.
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Fundamental research: Underlying mechanisms of disease and health
To make the right clinical decisions or develop effective diagnostic tests and treatments, it is important to understand the underlying mechanisms of a condition or behavior.
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The role of ceramide chain length distribution on the barrier properties of the skin lipid membranes
The skin barrier function is provided by the stratum corneum (SC). The lipids in the SC are composed of three lipid classes: ceramides (CERs), cholesterol (CHOL) and free fatty acids (FFAs) which form two crystalline lamellar structures. In the present study, we investigate the effect of CER chain length…
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The role of shame and guilt in the development of aggression
Adolescents with autism or hearing loss report fewer feelings of guilt and shame than their peers. However, guilt does still serve a ‘corrective function’ in this group. This is what Evelien Broekhof’s dissertation reveals. PhD defence on 4 June.
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Gradients of Europeanness in Colonial Africa: the case of the Portuguese in the Congo Free State (c. 1885-1908) (GRADIENTS)
The project GRADIENTS investigates what it meant to be European in colonial Africa where identification as European often did not depend on skin colour and was understood on a spectrum with many gradients.
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Social Anxiety and Normal Development
Why does social anxiety increase in adolescence and how does it grow out of control in some adolescents?
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Topic: Novelty and enrichment
One of the most crucial aspects of our behaviour is our motivation to explore novel environments and interact with new people. This became painfully clear during the COVID-19 lockdowns, when many people suffered from lack of new experiences and real-life social interactions. The relevance of novelty…
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Topic: Persistent physical symptoms
Persistent somatic symptoms are long term symptoms that lack a clear medical explanation. These symptoms have a high prevalence where most people know someone who experiences such symptoms or they experience such symptoms themselves. Symptoms can vary greatly in and between people. While one person…
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Topic: Aging and neuropsychological rehabilitation
Cognitive decline (amongst other problems with attention, concentration, memory) is a common symptom in patients with a variety of brain disorders and has been related to healthy ageing as well. People suffering from cognitive deficits are often significantly hampered in their day-to-day functioning…
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Programme structure
The research master's specialisation Clinical and Health Psychology consists of five main parts: the general courses, the specialisation-specific courses, the elective courses, a research internship and a thesis.
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The incongruity of misfit: A systematic literature review and research agenda
This research tries to create a coherent comprehension of misfit, enhance conceptual knowledge, highlight prevalent knowledge.
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The amorphous 6-string
This research intents to redefine the limits of the electric guitar.
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Gold nanorod photoluminescence: applications to imaging and temperature sensing
Promotor: M.A.G.J. Orrit
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Programme structure
You have ample opportunity to assemble your own study path in Cosmology. The courses cover the full spectrum from theoretical early universe to observational cosmology.
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What happens on the schoolyard? Sensors on clothing reveal painful patterns
Wat gebeurt er op het schoolplein? Sensoren op kleding openbaren pijnlijke patronen
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About the programme
The two-years MSc programme spans the entire spectrum of Analytical BioSciences, Biopharmaceutics, Drug Delivery Technology, Medicinal Chemistry, Pharmacology and Toxicology.
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Why Leiden University?
The Leiden Institute of Chemistry (LIC) offers a unique tailor-made programme in Chemistry. You can customize the programme to your own interests and ambitions with the help of your own personal mentor. Your study will focus on either Chemical Biology or Energy & Sustainability. During the Master's…
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Research
Through metabolism, biochemical processes give rise to the complexity of life. Acquired and inborn errors in metabolism underlie many diseases occurring in man. The challenge for present day medical biochemistry is to find, and integrate, pieces of information at molecular, cell and organismal level…
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Brave Steps
A step-by-step approach to building confidence in anxiety-prone young children.
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Clinical Psychology (MSc)
In the specialisation Clinical Psychology, part of the Master in Psychology, you gain extensive knowledge on the asessment and treatment of mental disorders.