A tried and tested medication for treating ADHD works differently than expected in the brains of healthy individuals during rest: rather than stimulating brain activity, it suppresses it.

Up to 50% of all children and adolescents growing up worldwide are exposed to at least one form of childhood adversity (CA), which is one of the strongest predictors for later-life psychopathology.

Neuroscientist Anne Hafkemeijer is able to distinguish two different forms of dementia using advanced imaging techniques. This is the first step towards early recognition of dementia in patients on the basis of brain networks. PhD defence 26 May.

An international partnership of brain researchers from 35 research centres - from the US to China - including the Leiden Institute for Brain and Cognition (LIBC), has collected resting-state functional MRI data from more than 1400 healthy volunteers and put the information online so that it is available…

In a recent mega-analysis, researchers from Leiden University aimed to clarify the contradictory findings of research into social anxiety disorder. They found that to obtain reliable research results having the largest possible sample size is important. Publication in NeuroImage:Clinical.

The brains of adolescents react more strongly to receiving rewards. This can lead to risky behaviour, but research in Leiden has shown that it also has a positive purpose: it makes learning easier. The publication of an article on the research findings led to a lot of media attention.

Novel language learning activates different neural processes than was previously thought. A Leiden research team has discovered parallel but separate contributions from the hippocampus and Broca's area, the learning centre in the left hemisphere. The right hemisphere of the brain also seems to play…

Fatemeh (Simin) Tabassi Mofrad has recently received a project grant (€ 25,000) from LUF/Gratama Foundation for her ideas in investigating sex-by-genotype interactions in brain functions. She has a multidisciplinary research perspective which enables her to look at research issues from different angles.…

Do medicines arrive in the right amount at the right spot in our brain? By making a model that depicts our brain in small 'brain blocks', Esmée Vendel tries to find an answer to this question. Her new, mathematical model predicts the concentration of medicines in the brain over time and space. Vendel…

Miranda Smit, Ineke van der Ham and colleagues have published a paper in Experimental Brain Research, entitled: Body ownership and the absence of touch: Approaching the rubber hand in- and outside peri-hand space.

For many years, scientists have observed a correlation between Alzheimer’s disease and a surplus of iron in the brain. However, a causal link between the two has not been proven yet. We lack knowledge concerning the specific form of iron that is involved in the development of neurodegenerative diseases.…

It was already known that social anxiety disorder often affects more than one person in the same family. But research by PhD student Janna Marie Bas-Hoogendam has now shown that there are genetic brain characteristics that are associated with social anxiety. The PhD ceremony will take place on 14 Ja…

The Pilgrims to America exhibition at Museum De Lakenhal inspires reflection. How far do you go in the quest for freedom? It focuses on the Pilgrims’ relationship with the University and which knowledge they took with them from Leiden.

For their research many neuropsychologists use the brain scanners at the LUMC. At the start of the pandemic, the rules for visiting the hospital became stricter and a large amount of psychology research looked as though it would fall through. Thanks to good protocols the researchers can now pick up…

There is greater variety in the size of men’s brains than of women’s. This could help explain why some psychiatric disorders such as ADHD and autism are more prevalent in boys. Leiden brain researcher Lara Wierenga has published an article about this in the international journal Cerebral Cortex.

There seem to be genes that influence how our brains develop over time. A large international consortium has discovered this with an extensive study. The results of the study were recently published in Nature Neuroscience.

On Sept. 29, Lara Wierenga, together with graphic designer Dirma Janse, presented their new book Atlas of our Brain. In the presence of fellow scientists and other interested parties, they shared some of the stunning illustrations and mind-boggling facts that can be found in the book.

Eveline Crone wrote a new edition of

May 12 is Mother's Day in many countries. Becoming a mother is no mean feat: brain scientist Elseline Hoekzema has shown that a woman's brain changes drastically during pregnancy. She explained how in TV show De Kennis van Nu.

Brain scanners have radically changed neurolinguistics. They are increasing our understanding of how the brain processes language. Professor Niels Schiller has produced a standard work on this.

Heightened activation of the striatum that adolescents show in response to reward is often associated with risk-taking and negative health consequences. This article in Nature Communications investigates a potential positive side of this heightened activation. It shows that the activity peak in late…

Aceruloplasminemia is a very rare, genetic disease accompagnied with iron accumulation that causes movement disorder and brain damage at early age.

The Leiden Institute for Brain and Cognition (LIBC) is concentrating increasingly on research into the role of the brain in language development. The institute has now set up the LIBC Language website that brings together all the information on this research.

It may seem as though adolescents do as they please, but they are more sensitive to their parents’ opinions than they would appear. The adolescent brain reacts strongly to parental criticism or praise. These are the results of a study by an interdisciplinary research group of psychologists and neuroscientists…

A unique multicenter study, including about 3,500 youth between 10 and 25 years old from across the globe, shows that artificial intelligence - specifically machine learning - is able to identify individuals with anxiety disorders based on their unique brain structure.

Why do some people with adverse childhood experiences develop mental health conditions whereas others do not? A Leiden research project is looking for volunteers aged between 18 and 24 to help us understand more about human resilience.

Parents appear to be extremely sensitive to feedback they receive about their child. Just how sensitive depends on the (‘rose-tinted’) glasses through which they look at their child. All this can be seen in the brain. Neuroscientist Lisanne van Houtum and her Leiden colleagues published on this issue…

The way in which written language is processed in the brain is a hot topic in cognitive research. Cognitive psychologist Rinus Verdonschot studied a Japanese script in which a single character can have up to three possible pronunciations. He discovered that all three are simultaneously activated in…

'With this artwork, I want to give the audience a glance into my overstimulated brain and that of other people with autism', says Jasmijn den Hoed. The Faculty of Social and Behavioural Sciences is exhibiting her artwork 'Overstimulated' in the restaurant near the blue wall during Autism Week 25 March…

ACPA’s PhD candidate and composer/flutist Ned McGowan will give a lecture at Café Chercher on March 27 called Speed in Music, Brain and Body.

The STW project Energy Efficient Computer-Brain Interaction (principal investigator for LIACS: dr. T.P. Stefanov) has been granted. Funding for LIACS: 1 PhD student + travel/equipment budget, project duration: 4 years.

On June 10, Michelle Achterberg received the prize for best dissertation from the Dutch Neurofederation, the network of Dutch neuroscientists, for her thesis 'Like me, ore else...'. Achterberg obtained her doctorate cum laude from the Gravitation Program 'Samen Uniek' of the Leiden Consortium on Individual…

Professor of Human Genetics Willeke van Roon will give her inaugural lecture on Monday 28 March entitled: ‘Translational research, where small parts make the bigger picture.’ She will emphasise how university medical centres should take responsibility for finding treatments for very rare diseases.

Stimulating the vagus nerve, which provides a direct link between the gut and brain, makes people pay less attention to sad facial expressions. This research study by psychologists Katerina Johnson and Laura Steenbergen is published in the journal Neuroscience.

We are all at home in familiar surroundings. Not only is this boring but it can also have a negative influence on our learning, explains cognitive neuropsychologist Judith Schomaker. ‘Discovering new environments gets our brain learning and remembering. We are now missing this stimulus.’

Leiden University will appoint Dr Anne-Laura van Harmelen as Professor of Brain, Security and Resilience at the Institute of Education and Child Studies with effect from 1 September 2020. She will focus on the brain in relation to the development of transgressive behaviour and its prevention and tre…

During adolescence, some young people have stable best-friend relationships, while others change best friends frequently. Developmental psychologist Lisa Schreuders has studied the brains of young adolescents: ‘It seems that friendships in your early years can have consequences for your friendships…

Deep-brain stimulation (DBS) is the most promising surgical treatment for movement and neuropsychiatric disorders, but is accompanied by unwanted side effects. Birte Forstmann, professor by special appointment, has been awarded a ERC Proof of Concept Grant to create an atlas of the human deep brain…

Nature, nurture and neural mechanisms of social emotion regulation in childhood

Neuroscientist Elseline Hoekzema receives a large European grant from the European Research Council (ERC). This ERC starting grant for promising young researchers allows her to investigate the effects of pregnancy on the brain in detail.

Young people tend to take more risks than children or adults. This trend is related to the reward centre in the brain, which is much more active when they are rewarded, PhD candidate Barbara Braams discovered. Personality, testosterone levels and social context also play a role in risk-taking.

‘We didn’t find any mechanisms in the brain for transmitting child abuse from generation to generation. What we did find is that experiences of neglect and abuse affect the brain differently,’ concludes Lisa van den Berg (Clinical Psychology). PhD defence 30 June.

It’s not a regular occurrence at Leiden University: two professors giving their inaugural lecture on the same day. Berna Güroğlu and Ellen de Bruijn specialise in related disciplines: they both research the influence of social context on processes in the brain – Güroğlu in adolescents and De Bruijn…

How does music affect a test subject’s brain? That was just one of the questions on the minds of the people who came to the LIBC public day to hear Rebecca Schaefer’s talk, as well as to hear from other top researchers about their investigations into music. The five woodwind players in the Calefax reed…

Hunter-gatherers acquire their food through complex gender-specific foraging techniques for a relatively stable and diverse supply of energy. New research indicates that this specialisation by boys and girls starts at a very young age. Most likely, this enabled the human species to evolve much larger…